Infant cholesterol and glycated haemoglobin concentrations vary widely-Associations with breastfeeding, infant diet and maternal biomarkers.
| Title: | Infant cholesterol and glycated haemoglobin concentrations vary widely-Associations with breastfeeding, infant diet and maternal biomarkers. |
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| Authors: | Øyri LKL; Department of Nutrition, University of Oslo, Oslo, Norway.; Bogsrud MP; Unit for Cardiac and Cardiovascular Genetics, Department of Medical Genetics, Oslo University Hospital, Oslo, Norway.; Norwegian National Advisory Unit on Familial Hypercholesterolemia, Department of Endocrinology, Morbid Obesity and Preventive Medicine, Oslo University Hospital, Oslo, Norway.; Kristiansen AL; Department of Nutrition, University of Oslo, Oslo, Norway.; Myhre JB; Department of Nutrition, University of Oslo, Oslo, Norway.; Retterstøl K; Department of Nutrition, University of Oslo, Oslo, Norway.; The Lipid Clinic, Department of Endocrinology, Morbid Obesity and Preventive Medicine, Oslo University Hospital, Oslo, Norway.; Brekke HK; Department of Nutrition, University of Oslo, Oslo, Norway.; Gundersen TE; Vitas AS, Oslo, Norway.; Andersen LF; Department of Nutrition, University of Oslo, Oslo, Norway.; Holven KB; Department of Nutrition, University of Oslo, Oslo, Norway.; Norwegian National Advisory Unit on Familial Hypercholesterolemia, Department of Endocrinology, Morbid Obesity and Preventive Medicine, Oslo University Hospital, Oslo, Norway. |
| Source: | Acta paediatrica (Oslo, Norway : 1992) [Acta Paediatr] 2020 Jan; Vol. 109 (1), pp. 115-121. Date of Electronic Publication: 2019 Aug 04. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Language: | English |
| Journal Info: | Publisher: Wiley-Blackwell Country of Publication: Norway NLM ID: 9205968 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1651-2227 (Electronic) Linking ISSN: 08035253 NLM ISO Abbreviation: Acta Paediatr Subsets: MEDLINE |
| Imprint Name(s): | Publication: 2007- : Oslo : Wiley-Blackwell; Original Publication: Oslo : Scandinavian University Press, c1992- |
| MeSH Terms: | Breast Feeding* ; Diet*; Cholesterol/*blood ; Glycated Hemoglobin/*metabolism; Biomarkers/blood ; Adult ; Cross-Sectional Studies ; Female ; Humans ; Infant ; Male ; Pilot Projects ; Reference Values |
| Abstract: | Aim: Elevated total cholesterol (TC) and glycated haemoglobin (HbA1c) are risk factors for cardiovascular disease; however, little is known about their determinants in infants. We aimed to describe TC and HbA1c concentrations in infants aged 8-14 months and explore the relation between infant TC, HbA1c, breastfeeding, infant diet, and maternal TC and HbA1c.; Methods: In this cross-sectional pilot study, mothers of infants aged 6 and 12 months were invited to complete a food frequency questionnaire and to take home-based dried blood spot samples from themselves and their infants.; Results: Among the 143 included infants, the mean (SD, range) concentration was 4.1 (0.8, 2.3-6.6) mmol/L for TC and 4.9 (0.4, 3.7-6.0)% for HbA1c. There was no significant difference between age groups and sexes. There was a positive relation between TC concentrations of all infants and mothers (B = 0.30 unadjusted, B = 0.32 adjusted, P |
| Comments: | Erratum in: Acta Paediatr. 2022 Oct;111(10):2044-2045. doi: 10.1111/apa.16418.. (PMID: 35678218) |
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| Grant Information: | International University of Oslo; International Eckbos Legate; International Blix Foundation for the Promotion of Medical Research; International National Advisory Unit on Familial Hypercholesterolemia, Oslo University Hospital; International Aktieselskabet Freia Chocolade Fabriks Medisinske Fond; International Throne Holst Foundation for Nutrition Research |
| Contributed Indexing: | Keywords: breastfeeding; cholesterol; diet; glycated haemoglobin |
| Substance Nomenclature: | 0 (Biomarkers); 97C5T2UQ7J (Cholesterol); 0 (Glycated Hemoglobin); 0 (hemoglobin A1c protein, human) |
| Entry Date(s): | Date Created: 20190713 Date Completed: 20210121 Latest Revision: 20260127 |
| Update Code: | 20260130 |
| DOI: | 10.1111/apa.14936 |
| PMID: | 31299108 |
| Database: | MEDLINE |
Journal Article; Research Support, Non-U.S. Gov't