Antifouling silicones based on surface-modifying additive amphiphiles.
| Title: | Antifouling silicones based on surface-modifying additive amphiphiles. |
|---|---|
| Authors: | Rufin MA; Department of Biomedical Engineering, Texas A&M University, College Station, TX, USA.; Ngo BKD; Department of Biomedical Engineering, Texas A&M University, College Station, TX, USA.; Barry ME; Department of Biomedical Engineering, Texas A&M University, College Station, TX, USA.; Page VM; Department of Biomedical Engineering, Texas A&M University, College Station, TX, USA.; Hawkins ML; Department of Biomedical Engineering, Texas A&M University, College Station, TX, USA.; Stafslien SJ; Center for Nanoscale Science and Engineering, North Dakota State University, Fargo, ND, USA.; Grunlan MA; Department of Biomedical Engineering and Department of Materials Science and Engineering, Texas A&M University, College Station, TX, USA, 5030 Emerging Technologies Building, College Station, TX 77843-3120. |
| Source: | Green materials [Green Mater] 2017 Mar; Vol. 5 (1), pp. 4-13. Date of Electronic Publication: 2017 Jul 20. |
| Publication Type: | Journal Article |
| Language: | English |
| Journal Info: | Publisher: ICE Publishing Country of Publication: England NLM ID: 101740310 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2049-1239 (Electronic) Linking ISSN: 20491220 NLM ISO Abbreviation: Green Mater Subsets: PubMed not MEDLINE |
| Imprint Name(s): | Original Publication: [Westminster] : ICE Publishing, [2013]- |
| Abstract: | Surface modifying additives (SMAs), which may be readily blended into silicones to improve anti-fouling behavior, must have excellent surface migration potential and must not leach into the aqueous environment. In this work, we evaluated the efficacy of a series of poly(ethylene oxide) (PEO)-based SMA amphiphiles which varied in terms of crosslinkability, siloxane tether length (m) and diblock versus triblock architectures. Specifically, crosslinkable, diblock PEO-silane amphiphiles with two oligodimethylsiloxane (ODMS) tether lengths [(EtO)3Si-(CH2)3-ODMS m -PEO8, m = 13 and 30] were compared to analogous non-crosslinkable, diblock (H-Si-ODMS m -PEO8) and triblock (PEO8-ODMS m -PEO8) SMAs. Prior to water conditioning, while all modified silicone coatings exhibited a high degree of water-driven surface restructuring, that prepared with the non-crosslinkable diblock SMA (m = 13) was the most hydrophilic. After conditioning, all modified silicone coatings were similarly hydrophilic and remained highly protein resistant, with the exception of PEO8-ODMS 30 -PEO8. Notably, despite twice the PEO content, triblock SMAs were not superior to diblock SMAs. For diblock SMAs, it was shown that water uptake and leaching were also similar whether or not the SMA was crosslinkable. |
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| Grant Information: | R01 DK095101 United States DK NIDDK NIH HHS |
| Contributed Indexing: | Keywords: ANTI-FOULING; POLYMERIC MATERIALS; SURFACE MODIFICATION |
| Entry Date(s): | Date Created: 20191102 Latest Revision: 20231014 |
| Update Code: | 20260130 |
| PubMed Central ID: | PMC6822677 |
| DOI: | 10.1680/jgrma.16.00013 |
| PMID: | 31673356 |
| Database: | MEDLINE |
Journal Article