Recurrence Rate in a Patient Treated with Colon Resection Followed by Chemotherapy in Comparison to a Patient Treated with Colon Resection without Chemotherapy.
| Title: | Recurrence Rate in a Patient Treated with Colon Resection Followed by Chemotherapy in Comparison to a Patient Treated with Colon Resection without Chemotherapy. |
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| Authors: | Alshehri KA; Medicine, College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Jeddah, SAU.; Altuwaylie TM; Medicine, College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Jeddah, SAU.; Fakieha A; Medicine, College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Jeddah, SAU.; AlGhamdi G; Medicine, College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Jeddah, SAU.; Alshahrani SM; Medicine, College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Jeddah, SAU.; Mikwar Z; Surgical Oncology, King Abdulaziz Medical City, Ministry of National Guard Health Affairs, Jeddah, SAU. |
| Source: | Cureus [Cureus] 2020 Apr 04; Vol. 12 (4), pp. e7544. Date of Electronic Publication: 2020 Apr 04. |
| Publication Type: | Journal Article |
| Language: | English |
| Journal Info: | Publisher: Cureus, Inc Country of Publication: United States NLM ID: 101596737 Publication Model: Electronic Cited Medium: Print ISSN: 2168-8184 (Print) Linking ISSN: 21688184 NLM ISO Abbreviation: Cureus Subsets: PubMed not MEDLINE |
| Imprint Name(s): | Original Publication: Palo Alto, CA : Cureus, Inc. |
| Abstract: | Given that colon cancer is one of the most prevalent cancers worldwide, it is essential to employ strategies to try to reduce its incidence and recurrence rate. Though colon cancer is a sporadic disease in the vast majority of cases, multiple risk factors are linked to this disease, namely, obesity and cigarette smoking. Additionally, not many studies have been done in Saudi Arabia studying the recurrence rate of colon cancer. Therefore, we conducted a retrospective cohort study at King Khalid Hospital, King Abdulaziz Medical City, National Guard Health Affairs (NGHA), Jeddah, Saudi Arabia to investigate the recurrence rate of colon cancer in patients treated with complete colon resection followed by chemotherapy versus patients treated with colon resection alone via electronic and paper medical records. A total of 120 patients were included in this study; 61 were males (50.8%) and 59 were females (49.2%). According to our findings, the recurrence rate in patients who underwent surgical resection with adjuvant chemotherapy was 15.6% (n = 10), while the recurrence rate in patients with surgery alone was 21.4% (n = 12). Cancer recurrence is associated with significant morbidity and mortality. Therefore, further studies should be done to investigate the recurrence rate in patients with risk factors to identify and deal with the causes of recurrence.; (Copyright © 2020, Alshehri et al.) |
| Competing Interests: | The authors have declared that no competing interests exist. |
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| Contributed Indexing: | Keywords: chemotherapy; colon cancer; colon cancer recurrence; colon resection; general surgery; jeddah; kingdom of saudi arabia (ksa); national guard health affairs (ngha); recurrence rate; without chemotherapy |
| Entry Date(s): | Date Created: 20200508 Latest Revision: 20240328 |
| Update Code: | 20260130 |
| PubMed Central ID: | PMC7199900 |
| DOI: | 10.7759/cureus.7544 |
| PMID: | 32377492 |
| Database: | MEDLINE |
Journal Article