Adjusted tight control blood glucose management in diabetic patients undergoing on pump coronary artery bypass graft. A randomized clinical trial.
| Title: | Adjusted tight control blood glucose management in diabetic patients undergoing on pump coronary artery bypass graft. A randomized clinical trial. |
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| Authors: | Javaherforoosh Zadeh F; Department of Anesthesia, Ahvaz Anesthesiology and Pain Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.; Azemati S; Anesthesiology and Critical Care Research Center, Shiraz University of Medical Sciences, Shiraz, Iran. |
| Source: | Journal of diabetes and metabolic disorders [J Diabetes Metab Disord] 2020 Jan 20; Vol. 19 (1), pp. 423-430. Date of Electronic Publication: 2020 Jan 20 (Print Publication: 2020). |
| Publication Type: | Journal Article |
| Language: | English |
| Journal Info: | Publisher: Springer International Publishing Country of Publication: Switzerland NLM ID: 101590741 Publication Model: eCollection Cited Medium: Print ISSN: 2251-6581 (Print) Linking ISSN: 22516581 NLM ISO Abbreviation: J Diabetes Metab Disord Subsets: PubMed not MEDLINE |
| Imprint Name(s): | Publication: 2018- : [Cham] : Springer International Publishing; Original Publication: 2011: Tehran : Tehran University of Medical Sciences, Endocrinology and Metabolism Research Institute |
| Abstract: | Background: Many of the patients who are undergoing Coronary Artery Bypass Graft have diabetes mellitus or metabolic syndrome and are at risk for hyperglycemia events.; Objective: The present study aimed to compare conventional glucose control with adjusted tight control in patients undergoing on-pump CABG.; Methods: This double -blind randomized clinical trial study was conducted in Shiraz, Iran, from September 2017-March 2018. Two consecutive groups of 75 patients undergoing elective on- pump coronary artery bypass graft surgery.; Intervention: The patients were divided into adjusted tight control of the blood glucose between 100 and 120 mg/dl and conventional method that the blood glucose maintained ≤200 mg/dl.; Primary Outcomes Were: mortality, sternal wound infection, cardiac arrhythmia, cerebrovascular attack, and acute renal failure.; Secondary Outcomes Included: duration of mechanical ventilation and length of ICU staying. The same main outcomes were evaluated after one month.; Statistical Analysis: The data were analyzed using SPSS version 20(SPSS, Chicago, IL). Group comparisons were performed using t-tests and Chi-square tests. Repeated measurement test was used for comparing blood glucose in two groups. Mann Whitney U test was compared duration of the mechanical ventilation and length of ICU staying. Statistical significance was defined as a p value |
| Competing Interests: | Competing interestsThe authors declare that they have no competing interests.Conflicting interestThere is no conflict of interest to be declared. |
| Comments: | Erratum in: J Diabetes Metab Disord. 2020 Feb 7;19(1):665. doi: 10.1007/s40200-020-00500-9.. (PMID: 32550640) |
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| Contributed Indexing: | Keywords: Cardiac surgery; Critically ill patient; Diabetes; Tight control of glucose |
| Entry Date(s): | Date Created: 20200619 Latest Revision: 20220415 |
| Update Code: | 20260130 |
| PubMed Central ID: | PMC7270305 |
| DOI: | 10.1007/s40200-020-00494-4 |
| PMID: | 32550193 |
| Database: | MEDLINE |
Journal Article