Virtual Histology of Cortical Thickness and Shared Neurobiology in 6 Psychiatric Disorders.
| Title: | Virtual Histology of Cortical Thickness and Shared Neurobiology in 6 Psychiatric Disorders. |
|---|---|
| Authors: | Patel Y; Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada.; Bloorview Research Institute, Holland Bloorview Kids Rehabilitation Hospital, Toronto, Ontario, Canada.; Parker N; Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada.; Bloorview Research Institute, Holland Bloorview Kids Rehabilitation Hospital, Toronto, Ontario, Canada.; Shin J; The Hospital for Sick Children, Toronto, Ontario, Canada.; Howard D; Krembil Centre for Neuroinformatics, Centre for Addiction and Mental Health, Toronto, Ontario, Canada.; French L; Krembil Centre for Neuroinformatics, Centre for Addiction and Mental Health, Toronto, Ontario, Canada.; Thomopoulos SI; Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Los Angeles.; Pozzi E; Orygen, The National Centre of Excellence in Youth Mental Health, Parkville, Australia.; Abe Y; Department of Psychiatry, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.; Abé C; Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.; Anticevic A; Department of Psychiatry, Yale University, New Haven, Connecticut.; Alda M; Department of Psychiatry, Dalhousie University, Halifax, Nova Scotia, Canada.; Aleman A; University of Groningen, University Medical Center Groningen, Department of Biomedical Sciences of Cells and Systems, Cognitive Neuroscience Center, Groningen, the Netherlands.; Alloza C; Department of Child and Adolescent Psychiatry, Institute of Psychiatry and Mental Health, Hospital General Universitario Gregorio Marañón, IiSGM, CIBERSAM, Spain.; Alonso-Lana S; FIDMAG Germanes Hospitalàries Research Foundation, Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Barcelona, Catalonia, Spain.; Ameis SH; The Centre for Addiction and Mental Health, Campbell Family Mental Health Research Institute, University of Toronto, Toronto, Ontario, Canada.; Anagnostou E; Department of Pediatrics University of Toronto, Ontario, Canada.; McIntosh AA; Division of Psychiatry, University of Edinburgh, Royal Edinburgh Hospital, Edinburgh, Scotland.; Arango C; Department of Child and Adolescent Psychiatry, Institute of Psychiatry and Mental Health, Hospital General Universitario Gregorio Marañón, IiSGM, School of Medicine, Universidad Complutense, CIBERSAM.; Arnold PD; The Mathison Centre for Mental Health Research & Education, Hotchkiss Brain Institute, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.; Asherson P; Social, Genetic and Developmental Psychiatry Centre; Institute of Psychiatry, Psychology and Neuroscience; King's College London, London, England.; Assogna F; Laboratory of Neuropsychiatry, IRCCS Santa Lucia Foundation, Rome, Italy.; Auzias G; INT UMR 7289, Aix-Marseille Université, CNRS, Aix-en-Provence, France.; Ayesa-Arriola R; Department of Psychiatry, Marqués de Valdecilla University Hospital, IDIVAL, School of Medicine, University of Cantabria; Centro de Investigación Biomédica en Red de Salud Mental, Santander, Spain.; Bakker G; Department of Psychiatry and Neuropsychology, School of Mental Health and Neuroscience, Maastricht University, the Netherlands.; Banaj N; Laboratory of Neuropsychiatry, IRCCS Santa Lucia Foundation, Rome, Italy.; Banaschewski T; Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Mannheim, Medical Faculty Mannheim/Heidelberg University, Mannheim, Germany.; Bandeira CE; Department of Genetics, Instituto de Biociências, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.; Baranov A; The Research Institute of Pediatrics and Child Health of the Central Clinical Hospital of the Russian Academy of Sciences of the Ministry of Science and Higher Education of the Russian Federation, Moscow, Russia.; Bargalló N; Magnetic Resonance Image Core Facility, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.; Bau CHD; Department of Genetics, Instituto de Biociências, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.; Baumeister S; Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Mannheim, Medical Faculty Mannheim/Heidelberg University, Mannheim, Germany.; Baune BT; University of Münster, Department of Psychiatry, Münster, Germany.; Bellgrove MA; Turner Institute for Brain and Mental Health, School of Psychological Sciences, Monash University, Melbourne, Australia.; Benedetti F; Psychiatry and Clinical Psychobiology, Division of Neuroscience, Scientific Institute Ospedale San Raffaele, Milano, Italy.; Bertolino A; Department of Basic Medical Science, Neuroscience and Sense Organs, University of Bari 'Aldo Moro', Bari, Italy.; Boedhoe PSW; Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Psychiatry, Department of Anatomy & Neuroscience, Amsterdam Neuroscience, Amsterdam, the Netherlands.; Boks M; Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Department of Psychiatry, Utrecht, the Netherlands.; Bollettini I; Psychiatry and Clinical Psychobiology, Division of Neuroscience, Scientific Institute Ospedale San Raffaele, Milano, Italy.; Del Mar Bonnin C; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Barcelona Bipolar Disorders and Depressive Unit, Hospital Clinic, Institute of Neurosciences, University of Barcelona, Barcelona, Spain.; Borgers T; University of Münster, Department of Psychiatry, Münster, Germany.; Borgwardt S; Department of Psychiatry, University of Basel, Basel, Switzerland.; Brandeis D; Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Mannheim, Medical Faculty Mannheim/Heidelberg University, Mannheim, Germany.; Brennan BP; McLean Hospital, Harvard Medical School, Belmont, Massachusetts.; Bruggemann JM; School of Psychiatry, University of New South Wales, Sydney, New South Wales, Australia.; Bülow R; Institute for Diagnostic Radiology and Neuroradiology, University Medicine Greifswald, Greifswald, Germany.; Busatto GF; Laboratory of Psychiatric Neuroimaging (LIM-21), Departamento e Instituto de Psiquiatria, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, Brazil.; Calderoni S; Department of Developmental Neuroscience - IRCCS Fondazione Stella Maris, Pisa, Italy.; Department of Clinical and Experimental Medicine, University of Pisa.; Calhoun VD; Tri-institutional Center for Translational Research in Neuroimaging and Data Science (TReNDS), Georgia State University, Georgia Institute of Technology, Emory University, Atlanta, Georgia.; Calvo R; Department of Child and Adolescent Psychiatry and Psychology, Hospital Clinic, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM); University of Barcelona, Spain.; Canales-Rodríguez EJ; FIDMAG Germanes Hospitalàries Research Foundation, Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Barcelona, Catalonia, Spain.; Cannon DM; Centre for Neuroimaging & Cognitive Genomics (NICOG), Clinical Neuroimaging Laboratory, NCBES Galway Neuroscience Centre, College of Medicine Nursing and Health Sciences, National University of Ireland Galway, H91 TK33 Galway, Ireland.; Carr VJ; School of Psychiatry, University of New South Wales, Randwick, New South Wales, Australia.; Cascella N; Department of Psychiatry, Johns Hopkins University School of Medicine, Baltimore, Maryland.; Cercignani M; Department of Neuroscience, Brighton and Sussex Medical School, University of Sussex, Brighton, England.; Chaim-Avancini TM; Laboratory of Psychiatric Neuroimaging (LIM-21), Departamento e Instituto de Psiquiatria, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, Brazil.; Christakou A; Centre for Integrative Neuroscience and Neurodynamics, School of Psychology and Clinical Language Sciences, University of Reading, Reading, England.; Coghill D; Departments of Paediatrics and Psychiatry, University of Melbourne, Melbourne, Australia.; Conzelmann A; Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University Hospital of Tübingen, Tübingen, Germany.; Crespo-Facorro B; Department of Psychiatry, Marqués de Valdecilla University Hospital, IDIVAL, School of Medicine, University of Cantabria; Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Santander, Spain; Hospital Universitario Virgen del Rocío, Sevilla, Spain; Departamento de Psiquiatria, Universidad de Sevilla, Instituto de Biomedicina de Sevilla (IBIS), Sevilla, Spain.; Cubillo AI; Department of Child and Adolescent Psychiatry, Institute of Psychiatry, Psychology and Neuroscience, King's College London, De Crespigny Park, London UK; Zurich Center for Neuroeconomics, University of Zurich, Zurich, Switzerland.; Cullen KR; Department of Psychiatry and Behavioral Sciences, University of Minnesota, Minneapolis, Minnesota.; Cupertino RB; Department of Genetics, Instituto de Biociências, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.; Daly E; Department of Forensic and Neurodevelopmental Sciences, Institute of Psychiatry, Psychology, and Neuroscience, King's College London, Sackler Institute for Translational Neurodevelopment, London, London, England.; Dannlowski U; University of Münster, Department of Psychiatry, Münster, Germany.; Davey CG; Orygen, Melbourne, Australia.; Denys D; Department of Psychiatry, Amsterdam UMC, Amsterdam, the Netherlands.; Deruelle C; INT UMR 7289, Aix-Marseille Université, CNRS, Aix-en-Provence, France.; Di Giorgio A; IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy.; Dickie EW; Campbell Family Mental Health Institute, Centre for Addiction and Mental Health, University of Toronto, Toronto, Ontario, Canada.; Dima D; Department of Psychology, School of Arts and Social Sciences, City, University of London, Northampton Square, Clerkenwell, London, England.; Dohm K; University of Münster, Department of Psychiatry, Münster, Germany.; Ehrlich S; Division of Psychological and Social Medicine and Developmental Neurosciences, Faculty of Medicine, TU Dresden, Dresden, Germany.; Ely BA; Department of Psychiatry and Biological Sciences, Albert Einstein College of Medicine, the Bronx, New York.; Erwin-Grabner T; University Medical Center Goettingen, Department of Psychiatry and Psychotherapy, Systems Neuroscience and Imaging in Psychiatry, Göettingen, Germany.; Ethofer T; Department of Psychiatry, University of Tuebingen, Tuebingen, Germany.; Fair DA; Behavioral Neuroscience Department, Oregon Health & Science University, Portland.; Fallgatter AJ; Department of Psychiatry, University of Tuebingen, Tuebingen, Germany.; Faraone SV; Departments of Psychiatry and of Neuroscience and Physiology, SUNY Upstate Medical University, Syracuse, New York.; Fatjó-Vilas M; FIDMAG Germanes Hospitalàries Research Foundation, Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Barcelona, Catalonia, Spain.; Fedor JM; Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania.; Fitzgerald KD; Child OCD and Anxiety Disorders Program, Department of Psychiatry, University of Michigan Medical School, Ann Arbor.; Ford JM; San Francisco VA Medical Center, San Francisco, California.; Frodl T; Department of Psychiatry, Trinity College Dublin, Dublin, Ireland.; Fu CHY; University of East London, School of Psychology, London, England.; Fullerton JM; Neuroscience Research Australia (NeuRA), Sydney, New South Wales, Australia.; Gabel MC; Department of Neuroscience, Brighton and Sussex Medical School, Brighton, England.; Glahn DC; Tommy Fuss Center for Neuropsychiatric Disease Research, Department of Psychiatry, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts.; Roberts G; School of Psychiatry, University of New South Wales, Randwick, New South Wales, Australia.; Gogberashvili T; Central Clinical Hospital of the Russian Academy Sciences, Moscow, Russia.; Goikolea JM; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Barcelona Bipolar Disorders and Depressive Unit, Hospital Clinic, Institute of Neurosciences, University of Barcelona, Barcelona, Spain.; Gotlib IH; Department of Psychology, Stanford University, Stanford, California.; Goya-Maldonado R; University Medical Center Goettingen, Department of Psychiatry and Psychotherapy, Systems Neuroscience and Imaging in Psychiatry, Göettingen, Germany.; Grabe HJ; Department of Psychiatry and Psychotherapy, University Medicine Greifswald, Greifswald, Germany.; Green MJ; School of Psychiatry, University of New South Wales, Randwick, New South Wales, Australia.; Grevet EH; Department of Psychiatry, Faculdade de Medicina, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.; Groenewold NA; Department of Psychiatry and Mental Health, University of Cape Town, Cape Town, South Africa.; Grotegerd D; University of Münster, Department of Psychiatry, Münster, Germany.; Gruber O; Section for Experimental Psychopathology and Neuroimaging, Department of General Psychiatry, Heidelberg University Hospital, Heidelberg, Germany.; Gruner P; Department of Psychiatry, Yale University, New Haven, Connecticut.; Guerrero-Pedraza A; FIDMAG Germanes Hospitalàries Research Foundation, Barcelona, Spain.; Gur RE; Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia.; Gur RC; Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia.; Haar S; Department of Bioengineering, Imperial College London, London, England.; Haarman BCM; Department of Psychiatry, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.; Haavik J; Department of Biomedicine, University of Bergen, Bergen, Norway.; Hahn T; University of Münster, Department of Psychiatry, Münster, Germany.; Hajek T; Department of Psychiatry, Dalhousie University, Halifax, Nova Scotia, Canada.; Harrison BJ; Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne and Melbourne Health, Melbourne, Victoria, Australia.; Harrison NA; Department of Neuroscience, Brighton and Sussex Medical School, University of Sussex, Brighton, England.; Hartman CA; University of Groningen, University Medical Center Groningen, Department of Psychiatry, Interdisciplinary Center Psychopathology and Emotion regulation (ICPE), Groningen, the Netherlands.; Whalley HC; Division of Psychiatry, University of Edinburgh, Royal Edinburgh Hospital, Edinburgh, Scotland.; Heslenfeld DJ; Department of Experimental Psychology, Vrije Universiteit, Amsterdam, Netherlands.; Hibar DP; Genentech Inc, South San Francisco, California.; Hilland E; Department of Psychology, University of Oslo, Oslo, Norway.; Hirano Y; Research Center for Child Mental Development, Chiba University, Chiba, Japan.; Ho TC; Department of Psychiatry and Weill Institute for Neurosciences, University of California, San Francisco.; Hoekstra PJ; University of Groningen, University Medical Center Groningen, Department of Child and Adolescent Psychiatry, Groningen, the Netherlands.; Hoekstra L; Radboud University Medical Center, Karakter University Center of Child And Adolescent Psychiatry, Nijmegen, the Netherlands.; Hohmann S; Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Mannheim, Medical Faculty Mannheim/Heidelberg University, Mannheim, Germany.; Hong LE; Department of Psychiatry, Maryland Psychiatric Research Center, University of Maryland School of Medicine, Baltimore, Maryland.; Höschl C; National Institute of Mental Health, Klecany, Czech Republic.; Høvik MF; Department of Clinical Medicine, University of Bergen, Bergen, Norway.; Howells FM; Neuroscience Institute, University of Cape Town, Cape Town, South Africa.; Nenadic I; Department of Psychiatry and Psychotherapy, Philipps University Marburg, Marburg, Germany.; Jalbrzikowski M; Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania.; James AC; University of Oxford, Oxford, England.; Janssen J; Department of Child and Adolescent Psychiatry, Institute of Psychiatry and Mental Health, Hospital General Universitario Gregorio Marañón, IiSGM, CIBERSAM, Spain.; Jaspers-Fayer F; Department of Psychiatry, University of British Columbia, Vancouver, British Columbia, Canada.; Xu J; Department of Internal Medicine, First Affiliated Hospital of Kunming Medical University, Kunming. China.; Jonassen R; Department of Psychology, University of Oslo, Oslo, Norway.; Karkashadze G; Research Institute of Pediatrics and child health of the Central clinical hospital of the Ministry of Science and Education, Moscow, Russia.; King JA; Division of Psychological and Social Medicine and Developmental Neurosciences, Faculty of Medicine, TU Dresden, Dresden, Germany.; Kircher T; Department of Psychiatry, Philipps-University Marburg, Marburg, Germany.; Kirschner M; Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada.; Koch K; Department of Neuroradiology, Klinikum Rechts der Isar, Technische Universität München, Munich, Germany.; Kochunov P; Department of Psychiatry, Maryland Psychiatric Research Center, University of Maryland School of Medicine, Baltimore, Maryland.; Kohls G; Child Neuropsychology Section, Department of Child and Adolescent Psychiatry, Psychosomatics, and Psychotherapy, University Hospital RWTH Aachen, Aachen, Germany.; Konrad K; Child Neuropsychology Section, University Hospital RWTH Aachen, German; JARA-Brain Institute II Molecular Neuroscience and Neuroimaging, Research Centre Juelich, Juelich, Germany.; Krämer B; Section for Experimental Psychopathology and Neuroimaging, Department of General Psychiatry, Heidelberg University Hospital, Heidelberg, Germany.; Krug A; Department of Psychiatry, Philipps-University Marburg, Marburg, Germany.; Department of Psychiatry and Psychotherapy, University of Bonn, Germany.; Kuntsi J; Social, Genetic and Developmental Psychiatry Centre; Institute of Psychiatry, Psychology and Neuroscience; King's College London, London, England.; Kwon JS; Department of Psychiatry, Seoul National University College of Medicine, Seoul, Korea.; Landén M; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.; Landrø NI; Department of Psychology, University of Oslo, Oslo, Norway.; Lazaro L; Department of Child and Adolescent Psychiatry and Psychology, Hospital Clinic, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM); University of Barcelona, Spain.; Lebedeva IS; Mental Health Research Center, Moscow, Russia.; Leehr EJ; University of Münster, Department of Psychiatry, Münster, Germany.; Lera-Miguel S; Department of Child and Adolescent Psychiatry and Psychology, Hospital Clinic, Barcelona, Spain.; Lesch KP; Division of Molecular Psychiatry, Center of Mental Health, University of Würzburg, Würzburg, Germany.; Lochner C; SA MRC Unit on Risk and Resilience in Mental Disorders, Department of Psychiatry, Stellenbosch University, Stellenbosch, South Africa.; Louza MR; Institute of Psychiatry, University of Sao Paulo, Sao Paulo, Brazil.; Luna B; Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania.; Lundervold AJ; Department of Biological and Medical psychology, University of Bergen, Bergen, Norway.; MacMaster FP; Departments of Psychiatry and Pediatrics, University of Calgary, Calgary, Alberta, Canada.; Maglanoc LA; University Centre for Information Technology, University of Oslo, Oslo, Norway.; Malpas CB; Developmental Imaging, Murdoch Children's Research Institute, Melbourne, Australia.; Portella MJ; Group of Research in Mental Health, Institut d'Investigació Biomèdica Sant Pau, IIBSant Pau; Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Barcelona, Spain.; Marsh R; Department of Psychiatry, Vagelos College of Physicians and Surgeons, Columbia University, New York, New York.; Martyn FM; Centre for Neuroimaging & Cognitive Genomics (NICOG), Clinical Neuroimaging Laboratory, NCBES Galway Neuroscience Centre, College of Medicine Nursing and Health Sciences, National University of Ireland Galway, H91 TK33 Galway, Ireland.; Mataix-Cols D; Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.; Mathalon DH; Department of Psychiatry and Weill Institute for Neurosciences, University of California, San Francisco.; McCarthy H; Department of Psychiatry, Trinity College Dublin, Dublin, Ireland.; McDonald C; Centre for Neuroimaging & Cognitive Genomics (NICOG), Clinical Neuroimaging Laboratory, NCBES Galway Neuroscience Centre, College of Medicine Nursing and Health Sciences, National University of Ireland Galway, H91 TK33 Galway, Ireland.; McPhilemy G; Centre for Neuroimaging & Cognitive Genomics (NICOG), Clinical Neuroimaging Laboratory, NCBES Galway Neuroscience Centre, College of Medicine Nursing and Health Sciences, National University of Ireland Galway, H91 TK33 Galway, Ireland.; Meinert S; University of Münster, Department of Psychiatry, Münster, Germany.; Menchón JM; Department of Psychiatry, Bellvitge University Hospital, Bellvitge Biomedical Research Institute-IDIBELL; Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Barcelona, Spain.; Minuzzi L; McMaster University, Mood Disorders Program, SJH Hamilton, Hamilton, Ontario, Canada.; Mitchell PB; School of Psychiatry, University of New South Wales, Randwick, New South Wales, Australia.; Moreno C; Department of Child and Adolescent Psychiatry, Institute of Psychiatry and Mental Health, Hospital General Universitario Gregorio Marañón, IiSGM, School of Medicine, Universidad Complutense, CIBERSAM.; Morgado P; Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal.; Muratori F; Department of Developmental Neuroscience - IRCCS Fondazione Stella Maris, Pisa, Italy.; Department of Clinical and Experimental Medicine, University of Pisa.; Murphy CM; Department of Forensic and Neurodevelopmental Science, King's College London, London, England.; Murphy D; Department of Forensic and Neurodevelopmental Sciences, Institute of Psychiatry Psychology and Neuroscience, King's College, London, England.; Mwangi B; Louis A. Faillace, MD, Department of Psychiatry and Behavioral Sciences, The University of Texas Health Science Center at Houston.; Nabulsi L; Centre for Neuroimaging & Cognitive Genomics (NICOG), Clinical Neuroimaging Laboratory, NCBES Galway Neuroscience Centre, College of Medicine Nursing and Health Sciences, National University of Ireland Galway, H91 TK33 Galway, Ireland.; Nakagawa A; Research Center for Child Mental Development, Chiba University, Chiba, Japan.; Nakamae T; Department of Psychiatry, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.; Namazova L; The Research Institute of Pediatrics and Child Health of the Central Clinical Hospital of the Russian Academy of Sciences of the Ministry of Science and Higher Education of the Russian Federation, Moscow, Russia.; Narayanaswamy J; OCD clinic, Department of Psychiatry, National Institute of Mental Health and Neurosciences (NIMHANS), Bangalore, India.; Jahanshad N; Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Los Angeles.; Nguyen DD; Department of Pediatrics, University of California, Irvine.; Nicolau R; Department of Child and Adolescent Psychiatry and Psychology, Hospital Clinic, Barcelona, Spain.; O'Gorman Tuura RL; Center for MR Research, University Children's Hospital, Zürich, Switzerland.; O'Hearn K; Department of Physiology and Pharmacology, Wake Forest School of Medicine, Winston-Salem, North Carolina.; Oosterlaan J; Emma Children's Hospital, Amsterdam UMC, University of Amsterdam, Emma Neuroscience Group, department of Pediatrics, Amsterdam Reproduction and Development, Amsterdam, the Netherlands.; Opel N; University of Münster, Department of Psychiatry, Münster, Germany.; Ophoff RA; Center for Neurobehavioral Genetics, University of California Los Angeles.; Oranje B; Department of Psychiatry, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands.; García de la Foz VO; Neuroimaging Unit, Technological Facilities, Valdecilla Biomedical Research Institute IDIVAL; Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Santander, Spain.; Overs BJ; Neuroscience Research Australia, Sydney, Australia.; Paloyelis Y; Department of Neuroimaging, Institute of Psychiatry, Psychology and Neuroscience, King's College London, De Crespigny Park, London, England.; Pantelis C; Melbourne Neuropsychiatry Centre, University of Melbourne, Melbourne, Australia.; Parellada M; Department of Child and Adolescent Psychiatry, Institute of Psychiatry and Mental Health, Hospital General Universitario Gregorio Marañón, IiSGM, School of Medicine, Universidad Complutense, CIBERSAM.; Pauli P; Department of Psychology (Biological Psychology, Clinical Psychology, and Psychotherapy), and Center of Mental Health, University of Würzburg, Würzburg, Germany.; Picó-Pérez M; Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal.; Picon FA; Department of Psychiatry, Faculdade de Medicina, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.; Piras F; Laboratory of Neuropsychiatry, IRCCS Santa Lucia Foundation, Rome, Italy.; Piras F; Laboratory of Neuropsychiatry, IRCCS Santa Lucia Foundation, Rome, Italy.; Plessen KJ; Division of Child and Adolescent Psychiatry, Department of Psychiatry, Lausanne University Hospital, Lausanne, Switzerland; Child and Adolescent Mental Health Center, Mental Health Services, Capital Region of Denmark, Denmark.; Pomarol-Clotet E; FIDMAG Germanes Hospitalàries Research Foundation, Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Barcelona, Catalonia, Spain.; Preda A; Department of Psychiatry and Human Behavior, University of California, Irvine.; Puig O; Department of Child and Adolescent Psychiatry and Psychology, Hospital Clinic, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM); University of Barcelona, Spain.; Quidé Y; School of Psychiatry, University of New South Wales, Randwick, New South Wales, Australia.; Neuroscience Research Australia (NeuRA), Sydney, New South Wales, Australia.; Radua J; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Barcelona Bipolar Disorders and Depressive Unit, Hospital Clinic, Institute of Neurosciences, University of Barcelona, Barcelona, Spain.; Ramos-Quiroga JA; Department of Psychiatry, Hospital Universitari Vall d'Hebron, Barcelona, Catalonia, Spain; Group of Psychiatry, Mental Health and Addictions, Vall d'Hebron Research Institute, Barcelona, Catalonia, Spain; Department of Psychiatry and Forensic Medicine, Universitat Autònoma de Barcelona, Barcelona, Catalonia, Spain.; Biomedical Network Research Centre on Mental Health (CIBERSAM), Barcelona, Catalonia, Spain.; Rasser PE; Priority Centre for Brain & Mental Health Research, The University of Newcastle, Callaghan, New South Wales, Australia.; Rauer L; Section for Experimental Psychopathology and Neuroimaging, Department of General Psychiatry, Heidelberg University Hospital, Heidelberg, Germany.; Reddy J; OCD clinic, Department of Psychiatry, National Institute of Mental Health and Neurosciences (NIMHANS), Bangalore, India.; Redlich R; University of Münster, Department of Psychiatry, Münster, Germany.; Reif A; Department of Psychiatry, Psychosomatic Medicine and Psychotherapy, University Hospital Frankfurt, Germany.; Reneman L; Department of Radiology and Nuclear Medicine, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands.; Repple J; University of Münster, Department of Psychiatry, Münster, Germany.; Retico A; National Institute for Nuclear Physics, Pisa Division, Pisa, Italy.; Richarte V; Department of Psychiatry, Hospital Universitari Vall d'Hebron, Barcelona, Catalonia, Spain; Group of Psychiatry, Mental Health and Addictions, Vall d'Hebron Research Institute, Barcelona, Catalonia, Spain; Department of Psychiatry and Forensic Medicine, Universitat Autònoma de Barcelona, Barcelona, Catalonia, Spain.; Biomedical Network Research Centre on Mental Health (CIBERSAM), Barcelona, Catalonia, Spain.; Richter A; Section for Experimental Psychopathology and Neuroimaging, Department of General Psychiatry, Heidelberg University Hospital, Heidelberg, Germany.; Rosa PGP; Laboratory of Psychiatric Neuroimaging (LIM-21), Departamento e Instituto de Psiquiatria, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, Brazil.; Rubia KK; Department of Child & Adolescent Psychiatry, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, England.; Hashimoto R; Department of Pathology of Mental Diseases, National Institute of Mental Health, National Center of Neurology and Psychiatry, Tokyo, Japan.; Sacchet MD; Center for Depression, Anxiety, and Stress Research, McLean Hospital, Harvard Medical School, Belmont, Massachusetts.; Salvador R; FIDMAG Germanes Hospitalàries Research Foundation, Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Barcelona, Catalonia, Spain.; Santonja J; Department of Child and Adolescent Psychiatry, Institute of Psychiatry and Mental Health, Hospital General Universitario Gregorio Marañón, IiSGM, Facultad de Psicologia, Universidad Autónoma de Madrid.; Sarink K; University of Münster, Department of Psychiatry, Münster, Germany.; Sarró S; FIDMAG Germanes Hospitalàries Research Foundation, Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Barcelona, Catalonia, Spain.; Satterthwaite TD; Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia.; Sawa A; Department of Psychiatry, Johns Hopkins University School of Medicine, Baltimore, Maryland.; Schall U; Priority Centre for Brain & Mental Health Research, The University of Newcastle, Callaghan, New South Wales, Australia.; Schofield PR; Neuroscience Research Australia, Sydney, New South Wales, Australia.; Schrantee A; Department of Radiology and Nuclear Medicine, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands.; Seitz J; Department of Child and Adolescent Psychiatry, RWTH Aachen University Hospital, Aachen, Germany.; Serpa MH; Laboratory of Psychiatric Neuroimaging (LIM-21), Departamento e Instituto de Psiquiatria, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, Brazil.; Setién-Suero E; Department of Psychiatry, Marqués de Valdecilla University Hospital, IDIVAL, School of Medicine, University of Cantabria; Centro de Investigación Biomédica en Red de Salud Mental, Santander, Spain.; Shaw P; National Human Genome Research Institute and National Institute of Mental Health, Bethesda, Maryland.; Shook D; Department of Psychiatry, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands.; Silk TJ; School of Psychology, Deakin University, Geelong, Melbourne, Australia.; Sim K; West Region, Institute of Mental Health, Singapore.; Simon S; Department of Psychiatry and Psychotherapy, Philipps University Marburg, Marburg, Germany.; Simpson HB; Columbia University Irving Medical Center, New York, New York.; Singh A; University Medical Center Goettingen, Department of Psychiatry and Psychotherapy, Systems Neuroscience and Imaging in Psychiatry, Göettingen, Germany.; Skoch A; National Institute of Mental Health, Klecany, Czech Republic.; Skokauskas N; Center for Child and Adolescent Mental Health, Institute of Mental Health, Norwegian University of Science and Technology, Trondheim, Norway.; Soares JC; Louis A. Faillace, MD, Department of Psychiatry and Behavioral Sciences, The University of Texas Health Science Center at Houston.; Soreni N; Pediatric OCD Consultation Clinic, Anxiety Treatment and Research Center, SJH Hamilton, Ontario, Canada.; Soriano-Mas C; Department of Psychiatry, Bellvitge University Hospital, Bellvitge Biomedical Research Institute-IDIBELL; Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Barcelona, Spain.; Spalletta G; Laboratory of Neuropsychiatry, IRCCS Santa Lucia Foundation, Rome, Italy.; Spaniel F; National Institute of Mental Health, Klecany, Czech Republic.; Lawrie SM; Division of Psychiatry, University of Edinburgh, Royal Edinburgh Hospital, Edinburgh, Scotland.; Stern ER; Department of Psychiatry, New York University School of Medicine, Nathan Kline Institute, New York.; Stewart SE; Department of Psychiatry, University of British Columbia, Vancouver, British Columbia, Canada.; Takayanagi Y; Department of Neuropsychiatry, University of Toyama Graduate School of Medicine and Pharmaceutical Sciences, Toyama, Japan.; Temmingh HS; Department of Psychiatry and Mental Health, University of Cape Town, Cape Town, South Africa.; Tolin DF; Anxiety Disorders Center, The Institute of Living, Hartford, Connecticut.; Tomecek D; National Institute of Mental Health, Klecany, Czech Republic.; Tordesillas-Gutiérrez D; Neuroimaging Unit, Technological Facilities, Valdecilla Biomedical Research Institute IDIVAL; Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Santander, Spain.; Tosetti M; Laboratory of Medical Physics and Magnetic Resonance - IRCCS Fondazione Stella Maris, Pisa, Italy.; Uhlmann A; Department of Psychiatry and Mental Health, University of Cape Town, Cape Town, South Africa.; van Amelsvoort T; Department of Psychiatry and Neuropsychology, Maastricht University, Maastricht, the Netherlands.; van der Wee NJA; Department of Psychiatry, Leiden University Medical Center, Leiden, the Netherlands.; van der Werff SJA; Department of Psychiatry, Leiden University Medical Center, Leiden, the Netherlands.; van Haren NEM; Department of Child and Adolescent Psychiatry/Psychology, Erasmus University Medical Centre, Rotterdam, the Netherlands.; van Wingen GA; Amsterdam UMC, University of Amsterdam, Department of Psychiatry, Amsterdam Neuroscience, Amsterdam, the Netherlands.; Vance A; Academic Child Psychiatry Unit, Department of Pediatrics, University of Melbourne, Royal Children's Hospital, Melbourne, Australia.; Vázquez-Bourgon J; Department of Psychiatry, Marqués de Valdecilla University Hospital, IDIVAL, School of Medicine, University of Cantabria; Centro de Investigación Biomédica en Red de Salud Mental, Santander, Spain.; Vecchio D; Laboratory of Neuropsychiatry, IRCCS Santa Lucia Foundation, Rome, Italy.; Venkatasubramanian G; OCD clinic, Department of Psychiatry, National Institute of Mental Health and Neurosciences (NIMHANS), Bangalore, India.; Vieta E; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Barcelona Bipolar Disorders and Depressive Unit, Hospital Clinic, Institute of Neurosciences, University of Barcelona, Barcelona, Spain.; Hospital Clinic, University of Barcelona, Spain.; Vilarroya O; Department of Psychiatry and Forensic Medicine, Autonomous University of Barcelona, Cerdanyola del Vallès, Barcelona, Spain.; Vives-Gilabert Y; Instituto ITACA, Universitat Politècnica de València, Valencia, Spain.; Voineskos AN; Campbell Family Mental Health Institute, Centre for Addiction and Mental Health, University of Toronto, Toronto, Ontario, Canada.; Völzke H; Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany.; von Polier GG; Department for Child and Adolescent Psychiatry, University Hospital RWTH Aachen, Aachen, Germany.; Walton E; Department of Psychology, University of Bath, Bath, England.; Weickert TW; School of Psychiatry, University of New South Wales, Sydney, New South Wales, Australia.; Weickert CS; School of Psychiatry, University of New South Wales, Sydney, New South Wales, Australia.; Weideman AS; Clinical Translational Neuroscience Laboratory, University of California Irvine, Irvine, CA; Center for the Neurobiology of Learning and Memory, University of California, Irvine.; Wittfeld K; German Center for Neurodegenerative Diseases (DZNE), Rostock/Greifswald, Germany.; Wolf DH; Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia.; Wu MJ; Louis A. Faillace, MD, Department of Psychiatry and Behavioral Sciences, The University of Texas Health Science Center at Houston.; Yang TT; University of California San Francisco, Department of Psychiatry, Division of Child and Adolescent Psychiatry, University of California, San Francisco, Weill Institute for Neurosciences.; Yang K; Department of Psychiatry, Johns Hopkins University School of Medicine, Baltimore, Maryland.; Yoncheva Y; Department of Child and Adolescent Psychiatry, New York University Child Study Center, Hassenfeld Children's Hospital at NYU Langone, New York.; Yun JY; Seoul National University Hospital, Seoul, Republic of Korea.; Cheng Y; Department of Psychiatry, First Affiliated Hospital of Kunming Medical University, Kunming, China.; Zanetti MV; Laboratory of Psychiatric Neuroimaging (LIM-21), Departamento e Instituto de Psiquiatria, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, Brazil.; Ziegler GC; Division of Molecular Psychiatry, Center of Mental Health, University of Würzburg, Würzburg, Germany.; Franke B; Departments of Human Genetics and Psychiatry, Radboud University Medical Center, Donders Institute for Brain, Cognition and Behaviour, Nijmegen, The Netherlands.; Hoogman M; Department of Human Genetics, Radboud University Medical Center, Donders Institute for Brain, Cognition and Behaviour, Nijmegen, The Netherlands.; Buitelaar JK; Department of Cognitive Neuroscience, Donders Institute for Brain, Cognition and Behaviour, Radboud UMC, Nijmegen, the Netherlands.; van Rooij D; Donders Centre for Cognitive Neuroimaging, Radboud University Medical Centre, Nijmegen, the Netherlands.; Andreassen OA; Norwegian Centre for Mental Disorders Research (NORMENT), Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; Ching CRK; Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Los Angeles.; Veltman DJ; Department of Psychiatry, Amsterdam UMC, location VUMC, Amsterdam, the Netherlands.; Schmaal L; Orygen, The National Centre of Excellence in Youth Mental Health, Parkville, Australia.; Centre for Youth Mental Health, The University of Melbourne, Melbourne, Australia.; Stein DJ; SAMRC Unit on Risk and Resilience in Mental Disorders, Department of Psychiatry and Neuroscience Institute, University of Cape Town, Cape Town, South Africa.; van den Heuvel OA; Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Psychiatry, Department of Anatomy & Neuroscience, Amsterdam Neuroscience, Amsterdam, the Netherlands.; Turner JA; Psychology Department and Neuroscience Institute, Georgia State University, Atlanta, Georgia.; van Erp TGM; Clinical Translational Neuroscience Laboratory, University of California Irvine, Irvine, CA; Center for the Neurobiology of Learning and Memory, University of California, Irvine.; Pausova Z; The Hospital for Sick Children, Toronto, Ontario, Canada.; Thompson PM; Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Los Angeles.; Paus T; Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada.; Bloorview Research Institute, Holland Bloorview Kids Rehabilitation Hospital, Toronto, Ontario, Canada.; Departments of Psychology and Psychiatry, University of Toronto, Toronto, Ontario, Canada. |
| Corporate Authors: | Writing Committee for the Attention-Deficit/Hyperactivity Disorder; Autism Spectrum Disorder; Bipolar Disorder; Major Depressive Disorder; Obsessive-Compulsive Disorder; and Schizophrenia ENIGMA Working Groups |
| Source: | JAMA psychiatry [JAMA Psychiatry] 2021 Jan 01; Vol. 78 (1), pp. 47-63. |
| Publication Type: | Journal Article |
| Language: | English |
| Journal Info: | Publisher: American Medical Association Country of Publication: United States NLM ID: 101589550 Publication Model: Print Cited Medium: Internet ISSN: 2168-6238 (Electronic) Linking ISSN: 2168622X NLM ISO Abbreviation: JAMA Psychiatry Subsets: MEDLINE |
| Imprint Name(s): | Original Publication: Chicago, IL : American Medical Association, [2013]- |
| MeSH Terms: | Attention Deficit Disorder with Hyperactivity/*pathology ; Autism Spectrum Disorder/*pathology ; Bipolar Disorder/*pathology ; Cerebral Cortex/*pathology ; Major Depressive Disorder/*pathology ; Fetal Development/*physiology ; Gene Expression/*physiology ; Human Development/*physiology ; Obsessive-Compulsive Disorder/*pathology ; Schizophrenia/*pathology; Attention Deficit Disorder with Hyperactivity/diagnostic imaging ; Autism Spectrum Disorder/diagnostic imaging ; Bipolar Disorder/diagnostic imaging ; Cerebral Cortex/cytology ; Cerebral Cortex/diagnostic imaging ; Cerebral Cortex/growth & development ; Major Depressive Disorder/diagnostic imaging ; Obsessive-Compulsive Disorder/diagnostic imaging ; Schizophrenia/diagnostic imaging ; Adolescent ; Adult ; Aged ; Aged, 80 and over ; Case-Control Studies ; Child ; Child, Preschool ; Cohort Studies ; Computational Biology ; Female ; Humans ; Magnetic Resonance Imaging ; Male ; Middle Aged ; Principal Component Analysis ; Young Adult |
| Abstract: | Importance: Large-scale neuroimaging studies have revealed group differences in cortical thickness across many psychiatric disorders. The underlying neurobiology behind these differences is not well understood.; Objective: To determine neurobiologic correlates of group differences in cortical thickness between cases and controls in 6 disorders: attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorder (ASD), bipolar disorder (BD), major depressive disorder (MDD), obsessive-compulsive disorder (OCD), and schizophrenia.; Design, Setting, and Participants: Profiles of group differences in cortical thickness between cases and controls were generated using T1-weighted magnetic resonance images. Similarity between interregional profiles of cell-specific gene expression and those in the group differences in cortical thickness were investigated in each disorder. Next, principal component analysis was used to reveal a shared profile of group difference in thickness across the disorders. Analysis for gene coexpression, clustering, and enrichment for genes associated with these disorders were conducted. Data analysis was conducted between June and December 2019. The analysis included 145 cohorts across 6 psychiatric disorders drawn from the ENIGMA consortium. The numbers of cases and controls in each of the 6 disorders were as follows: ADHD: 1814 and 1602; ASD: 1748 and 1770; BD: 1547 and 3405; MDD: 2658 and 3572; OCD: 2266 and 2007; and schizophrenia: 2688 and 3244.; Main Outcomes and Measures: Interregional profiles of group difference in cortical thickness between cases and controls.; Results: A total of 12 721 cases and 15 600 controls, ranging from ages 2 to 89 years, were included in this study. Interregional profiles of group differences in cortical thickness for each of the 6 psychiatric disorders were associated with profiles of gene expression specific to pyramidal (CA1) cells, astrocytes (except for BD), and microglia (except for OCD); collectively, gene-expression profiles of the 3 cell types explain between 25% and 54% of variance in interregional profiles of group differences in cortical thickness. Principal component analysis revealed a shared profile of difference in cortical thickness across the 6 disorders (48% variance explained); interregional profile of this principal component 1 was associated with that of the pyramidal-cell gene expression (explaining 56% of interregional variation). Coexpression analyses of these genes revealed 2 clusters: (1) a prenatal cluster enriched with genes involved in neurodevelopmental (axon guidance) processes and (2) a postnatal cluster enriched with genes involved in synaptic activity and plasticity-related processes. These clusters were enriched with genes associated with all 6 psychiatric disorders.; Conclusions and Relevance: In this study, shared neurobiologic processes were associated with differences in cortical thickness across multiple psychiatric disorders. These processes implicate a common role of prenatal development and postnatal functioning of the cerebral cortex in these disorders. |
| Comments: | Erratum in: JAMA Psychiatry. 2021 Jan 1;78(1):112. doi: 10.1001/jamapsychiatry.2020.3094.. (PMID: 32936223) |
| References: | Nature. 2019 Sep;573(7772):61-68. (PMID: 31435019); Science. 2015 Mar 6;347(6226):1138-42. (PMID: 25700174); Nat Neurosci. 2019 Mar;22(3):353-361. (PMID: 30692689); Neuroimage. 2006 Jul 1;31(3):968-80. (PMID: 16530430); Neuropsychopharmacology. 2016 Jan;41(1):3-23. (PMID: 26076834); Neuropsychopharmacology. 2015 Jan;40(1):1-3. (PMID: 25482168); Am J Psychiatry. 2018 Apr 1;175(4):359-369. (PMID: 29145754); Nat Genet. 2020 May;52(5):482-493. (PMID: 32341526); Dev Neurobiol. 2012 Jan;72(1):73-86. (PMID: 21761575); Cereb Cortex. 2019 Jul 22;29(8):3351-3362. (PMID: 30169567); Neuropathol Appl Neurobiol. 2004 Dec;30(6):615-23. (PMID: 15541002); Science. 2018 Jun 22;360(6395):. (PMID: 29930110); Arch Gen Psychiatry. 2001 Jun;58(6):545-53. (PMID: 11386983); Nat Neurosci. 2014 Oct;17(10):1418-1428. (PMID: 25174004); Mol Psychiatry. 2018 Apr;23(4):932-942. (PMID: 28461699); Schizophr Bull. 2001;27(3):457-76. (PMID: 11596847); Arch Gen Psychiatry. 2010 May;67(5):448-57. (PMID: 20439826); Nat Rev Neurosci. 2018 Mar 16;19(4):215-234. (PMID: 29545546); Mol Psychiatry. 2017 Jun;22(6):900-909. (PMID: 27137745); Arch Gen Psychiatry. 1986 Jan;43(1):31-5. (PMID: 3942472); Arch Gen Psychiatry. 1995 Oct;52(10):805-18; discussion 819-20. (PMID: 7575100); Am J Psychiatry. 2019 Jul 1;176(7):531-542. (PMID: 31014101); Nagoya J Med Sci. 2013 Feb;75(1-2):11-28. (PMID: 23544264); Mol Psychiatry. 2021 Aug;26(8):3795-3805. (PMID: 31900429); Biol Psychiatry. 2018 Feb 1;83(3):224-234. (PMID: 28967386); Lancet Neurol. 2015 May;14(5):532-46. (PMID: 25769423); Nature. 2012 Sep 20;489(7416):391-399. (PMID: 22996553); Dev Neurobiol. 2017 Apr;77(4):393-404. (PMID: 27390186); Nature. 2017 Oct 11;550(7675):204-213. (PMID: 29022597); Cereb Cortex. 2020 Mar 21;30(2):575-586. (PMID: 31240317); Front Neurosci. 2015 Sep 16;9:323. (PMID: 26441498); J Neurosci. 2017 Mar 22;37(12):3276-3293. (PMID: 28213444); Nat Rev Neurosci. 2008 Dec;9(12):947-57. (PMID: 19002191); Nature. 2014 Apr 10;508(7495):199-206. (PMID: 24695229); Am J Psychiatry. 2018 May 1;175(5):453-462. (PMID: 29377733); Cereb Cortex. 2018 Sep 1;28(9):3267-3277. (PMID: 28968835); Mol Psychiatry. 2021 Jun;26(6):2101-2110. (PMID: 33456050); J Stat Softw. 2012 Mar;46(11):. (PMID: 23050260); Nature. 2016 Feb 11;530(7589):177-83. (PMID: 26814963); Brain Struct Funct. 2019 Jan;224(1):191-203. (PMID: 30298291); Cancer Res. 1967 Feb;27(2):209-20. (PMID: 6018555); Biol Psychiatry. 2001 May 1;49(9):741-52. (PMID: 11331082); Nucleic Acids Res. 2020 Jan 8;48(D1):D845-D855. (PMID: 31680165); Mol Autism. 2014 Jan 10;5(1):3. (PMID: 24410870); Biol Psychiatry. 1999 May 1;45(9):1085-98. (PMID: 10331101); Nat Rev Neurosci. 2017 Dec;18(12):727-740. (PMID: 29070826); Curr Opin Neurobiol. 2019 Aug;57:62-70. (PMID: 30743178); JAMA Psychiatry. 2014 Dec 1;71(12):1323-31. (PMID: 25271938); Expert Rev Neurother. 2009 Jul;9(7):1059-71. (PMID: 19589054); Elife. 2018 Dec 18;7:. (PMID: 30561325); Biol Psychiatry. 2018 Nov 1;84(9):644-654. (PMID: 29960671); Nature. 2011 Oct 26;478(7370):519-23. (PMID: 22031444); Transl Psychiatry. 2020 Mar 20;10(1):100. (PMID: 32198361); Neuroimage. 2012 Aug 15;62(2):774-81. (PMID: 22248573) |
| Grant Information: | P50 MH094268 United States MH NIMH NIH HHS; R01 EB015611 United States EB NIBIB NIH HHS; UL1 TR001863 United States TR NCATS NIH HHS; G0802594 United Kingdom MRC_ Medical Research Council; T32 AG058507 United States AG NIA NIH HHS; IK6 CX002519 United States CX CSRD VA; K01 MH112774 United States MH NIMH NIH HHS; MC_PC_17209 United Kingdom MRC_ Medical Research Council; K23 MH115206 United States MH NIMH NIH HHS; U01 DA041148 United States DA NIDA NIH HHS; R01 MH119219 United States MH NIMH NIH HHS; R01 MH115357 United States MH NIMH NIH HHS; S10 OD023696 United States OD NIH HHS |
| Entry Date(s): | Date Created: 20200829 Date Completed: 20220117 Latest Revision: 20260127 |
| Update Code: | 20260130 |
| PubMed Central ID: | PMC7450410 |
| DOI: | 10.1001/jamapsychiatry.2020.2694 |
| PMID: | 32857118 |
| Database: | MEDLINE |
Journal Article