Family History of Eating Disorder and the Broad Autism Phenotype in Autism.
| Title: | Family History of Eating Disorder and the Broad Autism Phenotype in Autism. |
|---|---|
| Authors: | Barrionuevo BA; University of Miami Miller School of Medicine, Miami, FL, USA.; Chowdhury AR; University of Miami Miller School of Medicine, Miami, FL, USA.; Lee JM; University of Miami Miller School of Medicine, Miami, FL, USA.; John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA.; Dueker ND; University of Miami Miller School of Medicine, Miami, FL, USA.; John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA.; Martin ER; University of Miami Miller School of Medicine, Miami, FL, USA.; John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA.; Pericak-Vance MA; University of Miami Miller School of Medicine, Miami, FL, USA.; John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA.; Cuccaro M; University of Miami Miller School of Medicine, Miami, FL, USA.; John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA. |
| Source: | Autism research : official journal of the International Society for Autism Research [Autism Res] 2020 Sep; Vol. 13 (9), pp. 1573-1581. Date of Electronic Publication: 2020 Sep 05. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| Language: | English |
| Journal Info: | Publisher: John Wiley & Sons, Inc Country of Publication: United States NLM ID: 101461858 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1939-3806 (Electronic) Linking ISSN: 19393806 NLM ISO Abbreviation: Autism Res Subsets: MEDLINE |
| Imprint Name(s): | Original Publication: Hoboken, NJ : John Wiley & Sons, Inc. |
| MeSH Terms: | Family Health*/statistics & numerical data ; Health Surveys*; Autistic Disorder/*complications ; Feeding and Eating Disorders/*complications; Autistic Disorder/epidemiology ; Feeding and Eating Disorders/epidemiology ; Mothers/psychology ; Mothers/statistics & numerical data ; Siblings/psychology ; Adult ; Female ; Humans ; Male ; Phenotype |
| Abstract: | Autism features occur frequently among individuals with eating disorders (ED). This co-occurrence is not well understood but there is speculation that select traits (e.g., rigidity) are common to both autism and ED. To explore the co-occurrence of autistic traits and ED features, we used the Simons Simplex Collection (SSC; N = 2,623 families) to test whether first-degree relatives of individuals with autism with a history of ED features had more autism traits, as measured by the Broad Autism Phenotype Questionnaire (BAP-Q), compared to relatives with no history of ED. The frequency of individuals with ED features was 2.2% (N = 57) among mothers, |
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| Grant Information: | R01 GM105004 United States GM NIGMS NIH HHS; R01 HD057284 United States NH NIH HHS; R01 HD047417 United States NH NIH HHS |
| Contributed Indexing: | Keywords: broad autism phenotype; co-morbid conditions; family studies; phenotype; restricted/repetitive behaviors |
| Entry Date(s): | Date Created: 20200905 Date Completed: 20210701 Latest Revision: 20210701 |
| Update Code: | 20260130 |
| DOI: | 10.1002/aur.2378 |
| PMID: | 32888262 |
| Database: | MEDLINE |
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't