Postbiotics against Pathogens Commonly Involved in Pediatric Infectious Diseases.
| Title: | Postbiotics against Pathogens Commonly Involved in Pediatric Infectious Diseases. |
|---|---|
| Authors: | Mantziari A; Functional Foods Forum, Faculty of Medicine, University of Turku, 20520 Turku, Finland.; Salminen S; Functional Foods Forum, Faculty of Medicine, University of Turku, 20520 Turku, Finland.; Szajewska H; Department of Paediatrics at the Medical University of Warsaw, 02091 Warsaw, Poland.; Malagón-Rojas JN; Facultad de Medicina, Universidad El Bosque, 110121 Bogotá, Colombia.; Instituto Nacional de Salud de Colombia, 111321 Bogotá, Colombia. |
| Source: | Microorganisms [Microorganisms] 2020 Sep 30; Vol. 8 (10). Date of Electronic Publication: 2020 Sep 30. |
| Publication Type: | Journal Article; Review |
| Language: | English |
| Journal Info: | Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 101625893 Publication Model: Electronic Cited Medium: Print ISSN: 2076-2607 (Print) Linking ISSN: 20762607 NLM ISO Abbreviation: Microorganisms Subsets: PubMed not MEDLINE |
| Imprint Name(s): | Original Publication: Basel, Switzerland : MDPI AG, [2013]- |
| Abstract: | The Sustainable Development goals for 2020 included reducing all causes associated with infant and perinatal mortality in their priorities. The use of compounds with bioactive properties has been proposed as a therapeutic strategy due to their stimulating effect on the host's immune system. Additionally, biotherapeutic products such as postbiotics, tentatively defined as compounds produced during a fermentation process that support health and well-being, promote intestinal barrier integrity without posing considerable risks to children's health. Although this is a concept in development, there are increasing studies in the field of nutrition, chemistry, and health that aim to understand how postbiotics can help prevent different types of infections in priority populations such as minors under the age of five. The present review aims to describe the main mechanisms of action of postbiotics. In addition, it presents the available current evidence regarding the effects of postbiotics against pathogens commonly involved in pediatric infections. Postbiotics may constitute a safe alternative capable of modulating the cellular response and stimulating the host's humoral response. |
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| Contributed Indexing: | Keywords: children; common infectious diseases; postbiotics; probiotics; public health |
| Entry Date(s): | Date Created: 20201003 Latest Revision: 20240330 |
| Update Code: | 20260130 |
| PubMed Central ID: | PMC7601467 |
| DOI: | 10.3390/microorganisms8101510 |
| PMID: | 33008065 |
| Database: | MEDLINE |
Journal Article; Review