Urethrocutaneous fistulas after voluntary medical male circumcision for HIV prevention-15 African Countries, 2015-2019.
| Title: | Urethrocutaneous fistulas after voluntary medical male circumcision for HIV prevention-15 African Countries, 2015-2019. |
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| Authors: | Lucas T; Division of Global HIV and Tuberculosis, Centers for Disease Control and Prevention, Atlanta, GA, USA. tlucas@cdc.gov.; Hines JZ; Division of Global HIV and Tuberculosis, Centers for Disease Control and Prevention, Atlanta, GA, USA.; Samuelson J; Global HIV, Hepatitis, and STIs Programmes, World Health Organization, Geneva, Switzerland.; Hargreave T; Department of Surgery, Edinburgh University, Scotland, UK.; Davis SM; Division of Global HIV and Tuberculosis, Centers for Disease Control and Prevention, Atlanta, GA, USA.; Fellows I; Fellows Statistics, Contractor, Centers for Disease Control and Prevention, San Diego, CA, USA.; Prainito A; U.S. Office of the Global HIV/AIDS Coordinator, Washington, DC, USA.; Watts DH; U.S. Office of the Global HIV/AIDS Coordinator, Washington, DC, USA.; Kiggundu V; Office of HIV/AIDS, U.S. Agency for International Development, Washington, DC, USA.; Thomas AG; Department of Defense, Defense Health Agency, San Diego, CA, USA.; Ntsuape OC; Ministry of Health and Wellness, Gaborone, Botswana.; Dare K; Division of Global HIV and Tuberculosis, Centers for Disease Control and Prevention, Gaborone, Botswana.; Odoyo-June E; Division of Global HIV and Tuberculosis, Centers for Disease Control and Prevention, Nairobi, Kenya.; Soo L; U.S. Agency for International Development, Nairobi, Kenya.; Toti-Mokoteli L; Ministry of Health, Maseru, Lesotho.; Manda R; U.S. Agency for International Development, Maseru, Lesotho.; Kapito M; Ministry of Health, Lilongwe, Malawi.; Msungama W; Division of Global HIV and Tuberculosis, Centers for Disease Control and Prevention, Lilongwe, Malawi.; Odek J; U.S. Agency for International Development, Lilongwe, Malawi.; Come J; Ministry of Health, Maputo, Mozambique.; Canda M; Division of Global HIV and Tuberculosis, Centers for Disease Control and Prevention, Maputo, Mozambique.; Gaspar N; U.S. Agency for International Development, Maputo, Mozambique.; Mekondjo A; Ministry of Health and Social Services, Windhoek, Namibia.; Zemburuka B; Division of Global HIV and Tuberculosis, Centers for Disease Control and Prevention, Windhoek, Namibia.; Bonnecwe C; National Department of Health, Pretoria, South Africa.; Vranken P; Division of Global HIV and Tuberculosis, Centers for Disease Control and Prevention, Pretoria, South Africa.; Mmbando S; Ministry of Health, Dar es Salaam, Tanzania.; Simbeye D; Division of Global HIV and Tuberculosis, Centers for Disease Control and Prevention, Dar es Salaam, Tanzania.; Rwegerera F; U.S. Agency for International Development, Dar es Salaam, Tanzania.; Wamai N; Division of Global HIV and Tuberculosis, Centers for Disease Control and Prevention, Kampala, Uganda.; Kyobutungi S; U.S. Agency for International Development, Kampala, Uganda.; Zulu JE; Ministry of Health, Lusaka, Zambia.; Chituwo O; Division of Global HIV and Tuberculosis, Centers for Disease Control and Prevention, Lusaka, Zambia.; Xaba S; Ministry of Health and Child Care, Harare, Zimbabwe.; Mandisarisa J; Division of Global HIV and Tuberculosis, Centers for Disease Control and Prevention, Harare, Zimbabwe.; Toledo C; Division of Global HIV and Tuberculosis, Centers for Disease Control and Prevention, Atlanta, GA, USA. |
| Source: | BMC urology [BMC Urol] 2021 Feb 12; Vol. 21 (1), pp. 23. Date of Electronic Publication: 2021 Feb 12. |
| Publication Type: | Journal Article |
| Language: | English |
| Journal Info: | Publisher: BioMed Central Country of Publication: England NLM ID: 100968571 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2490 (Electronic) Linking ISSN: 14712490 NLM ISO Abbreviation: BMC Urol Subsets: MEDLINE |
| Imprint Name(s): | Original Publication: London : BioMed Central, [2001- |
| MeSH Terms: | Circumcision, Male/*adverse effects ; Cutaneous Fistula/*etiology ; Postoperative Complications/*etiology ; Urethral Diseases/*etiology ; Urinary Fistula/*etiology; Cutaneous Fistula/epidemiology ; HIV Infections/prevention & control ; Postoperative Complications/epidemiology ; Urethral Diseases/epidemiology ; Urinary Fistula/epidemiology ; Adolescent ; Africa ; Child ; Humans ; Male ; Retrospective Studies ; Time Factors |
| Abstract: | Background: Voluntary medical male circumcision (VMMC) is an HIV prevention strategy recommended to partially protect men from heterosexually acquired HIV. From 2015 to 2019, the President's Emergency Plan for AIDS Relief (PEPFAR) has supported approximately 14.9 million VMMCs in 15 African countries. Urethrocutaneous fistulas, abnormal openings between the urethra and penile skin through which urine can escape, are rare, severe adverse events (AEs) that can occur with VMMC. This analysis describes fistula cases, identifies possible risks and mechanisms of injury, and offers mitigation actions.; Methods: Demographic and clinical program data were reviewed from all reported fistula cases during 2015 to 2019, descriptive analyses were performed, and an odds ratio was calculated by patient age group.; Results: In total, 41 fistula cases were reported. Median patient age for fistula cases was 11 years and 40/41 (98%) occurred in patients aged |
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| Grant Information: | 001 International WHO_ World Health Organization |
| Contributed Indexing: | Keywords: Fistula; HIV; Intraoperative complications; Male circumcision |
| Entry Date(s): | Date Created: 20210213 Date Completed: 20210722 Latest Revision: 20250530 |
| Update Code: | 20260130 |
| PubMed Central ID: | PMC7881669 |
| DOI: | 10.1186/s12894-021-00790-y |
| PMID: | 33579261 |
| Database: | MEDLINE |
Journal Article