Neurophysiological mechanisms of chiropractic spinal manipulation for spine pain.
| Title: | Neurophysiological mechanisms of chiropractic spinal manipulation for spine pain. |
|---|---|
| Authors: | Gevers-Montoro C; Department of Anatomy, Université du Québec à Trois-Rivières, Trois-Rivières, QC, Canada.; CogNAC Research Group, Université du Québec à Trois-Rivières, Trois-Rivières, QC, Canada.; Madrid College of Chiropractic - RCU María Cristina, Madrid, Spain.; Provencher B; Department of Anatomy, Université du Québec à Trois-Rivières, Trois-Rivières, QC, Canada.; CogNAC Research Group, Université du Québec à Trois-Rivières, Trois-Rivières, QC, Canada.; Descarreaux M; Department of Anatomy, Université du Québec à Trois-Rivières, Trois-Rivières, QC, Canada.; GRAN Research Group, Université du Québec à Trois-Rivières, Trois-Rivières, QC, Canada.; Ortega de Mues A; Madrid College of Chiropractic - RCU María Cristina, Madrid, Spain.; Piché M; Department of Anatomy, Université du Québec à Trois-Rivières, Trois-Rivières, QC, Canada.; CogNAC Research Group, Université du Québec à Trois-Rivières, Trois-Rivières, QC, Canada. |
| Source: | European journal of pain (London, England) [Eur J Pain] 2021 Aug; Vol. 25 (7), pp. 1429-1448. Date of Electronic Publication: 2021 Apr 15. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't; Review |
| Language: | English |
| Journal Info: | Publisher: Wiley Country of Publication: England NLM ID: 9801774 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-2149 (Electronic) Linking ISSN: 10903801 NLM ISO Abbreviation: Eur J Pain Subsets: MEDLINE |
| Imprint Name(s): | Publication: 2012- : Chichester, UK : Wiley; Original Publication: London ; Philadelphia : Saunders, c1997- |
| MeSH Terms: | Chiropractic* ; Manipulation, Chiropractic* ; Manipulation, Spinal*; Back Pain/therapy ; Neck Pain/therapy ; Humans ; Placebos |
| Abstract: | Together, neck pain and back pain are the first cause of disability worldwide, accounting for more than 10% of the total years lived with disability. In this context, chiropractic care provides a safe and effective option for the management of a large proportion of these patients. Chiropractic is a healthcare profession mainly focused on the spine and the treatment of spinal disorders, including spine pain. Basic studies have examined the influence of chiropractic spinal manipulation (SM) on a variety of peripheral, spinal and supraspinal mechanisms involved in spine pain. While spinal cord mechanisms of pain inhibition contribute at least partly to the pain-relieving effects of chiropractic treatments, the evidence is weaker regarding peripheral and supraspinal mechanisms, which are important components of acute and chronic pain. This narrative review highlights the most relevant mechanisms of pain relief by SM and provides a perspective for future research on SM and spine pain, including the validation of placebo interventions that control for placebo effects and other non-specific effects that may be induced by SM. SIGNIFICANCE: Spinal manipulation inhibits back and neck pain partly through spinal segmental mechanisms and potentially through peripheral mechanisms regulating inflammatory responses. Other mechanisms remain to be clarified. Controls and placebo interventions need to be improved in order to clarify the contribution of specific and non-specific effects to pain relief by spinal manipulative therapy.; (© 2021 European Pain Federation - EFIC®.) |
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| Grant Information: | Canada CIHR |
| Contributed Indexing: | Keywords: low back pain; manual therapy; neck pain; pain inhibition; placebo; spinal manipulative therapy |
| Substance Nomenclature: | 0 (Placebos) |
| Entry Date(s): | Date Created: 20210331 Date Completed: 20210811 Latest Revision: 20220531 |
| Update Code: | 20260130 |
| DOI: | 10.1002/ejp.1773 |
| PMID: | 33786932 |
| Database: | MEDLINE |
Journal Article; Research Support, Non-U.S. Gov't; Review