Genetic mapping and phenotypic analysis of shotH.3.2 in Drosophila melanogaster.
| Title: | Genetic mapping and phenotypic analysis of shotH.3.2 in Drosophila melanogaster. |
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| Authors: | Talley EM; University of Evansville, Evansville, IN USA.; Watts CT; University of Evansville, Evansville, IN USA.; Aboyer S; Illinois State University, Normal, IL USA.; Adamson MG; University of Evansville, Evansville, IN USA.; Akoto HA; Illinois State University, Normal, IL USA.; Altemus H; Frostburg State University, Frostburg, MD USA.; Avella PJ; Illinois State University, Normal, IL USA.; Bailey R; University of Evansville, Evansville, IN USA.; Bell ER; University of Evansville, Evansville, IN USA.; Bell KL; University of Evansville, Evansville, IN USA.; Breneman K; University of Evansville, Evansville, IN USA.; Burkhart JS; Illinois State University, Normal, IL USA.; Chanley LJ; University of Evansville, Evansville, IN USA.; Cook SS; University of Evansville, Evansville, IN USA.; DesLaurier MT; Illinois State University, Normal, IL USA.; Dorsey TR; Illinois State University, Normal, IL USA.; Doyle CJ; University of Evansville, Evansville, IN USA.; Egloff ME; University of Evansville, Evansville, IN USA.; Fasawe AS; Illinois State University, Normal, IL USA.; Garcia KK; Frostburg State University, Frostburg, MD USA.; Graves NP; Frostburg State University, Frostburg, MD USA.; Gray TK; Illinois State University, Normal, IL USA.; Gustafson EM; Illinois State University, Normal, IL USA.; Hall MJ; Illinois State University, Normal, IL USA.; Hayes JD; University of Evansville, Evansville, IN USA.; Holic LJ; Illinois State University, Normal, IL USA.; Jarvis BA; Illinois State University, Normal, IL USA.; Klos PS; Illinois State University, Normal, IL USA.; Kritzmire S; University of Evansville, Evansville, IN USA.; Kuzovko L; Illinois State University, Normal, IL USA.; Lainez E; Frostburg State University, Frostburg, MD USA.; McCoy S; Frostburg State University, Frostburg, MD USA.; Mierendorf JC; Illinois State University, Normal, IL USA.; Neri NA; Illinois State University, Normal, IL USA.; Neville CR; Frostburg State University, Frostburg, MD USA.; Osborn K; Illinois State University, Normal, IL USA.; Parker K; Frostburg State University, Frostburg, MD USA.; Parks ME; Illinois State University, Normal, IL USA.; Peck K; University of Evansville, Evansville, IN USA.; Pitt R; Illinois State University, Normal, IL USA.; Platta ME; Illinois State University, Normal, IL USA.; Powell B; Frostburg State University, Frostburg, MD USA.; Rodriguez K; University of Evansville, Evansville, IN USA.; Ruiz C; Illinois State University, Normal, IL USA.; Schaefer MN; University of Evansville, Evansville, IN USA.; Shields AB; University of Evansville, Evansville, IN USA.; Smiley JB; Frostburg State University, Frostburg, MD USA.; Stauffer B; Frostburg State University, Frostburg, MD USA.; Straub D; University of Evansville, Evansville, IN USA.; Sweeney JL; Frostburg State University, Frostburg, MD USA.; Termine KM; Illinois State University, Normal, IL USA.; Thomas B; Frostburg State University, Frostburg, MD USA.; Toth SD; University of Evansville, Evansville, IN USA.; Veile TR; Illinois State University, Normal, IL USA.; Walker KS; Frostburg State University, Frostburg, MD USA.; Webster PN; University of Evansville, Evansville, IN USA.; Woodard BJ; University of Evansville, Evansville, IN USA.; Yoder QL; University of Evansville, Evansville, IN USA.; Young MK; University of Evansville, Evansville, IN USA.; Zeedyk ML; Illinois State University, Normal, IL USA.; Ziegler LN; Illinois State University, Normal, IL USA.; Bieser KL; Nevada State College, Henderson, NV USA.; Puthoff DP; Frostburg State University, Frostburg, MD USA.; Stamm J; University of Evansville, Evansville, IN USA.; Vrailas-Mortimer AD; Illinois State University, Normal, IL USA.; Kagey JD; University of Detroit Mercy, Detroit, MI USA.; Merkle JA; University of Evansville, Evansville, IN USA. |
| Source: | MicroPublication biology [MicroPubl Biol] 2021 Jul 13; Vol. 2021. Date of Electronic Publication: 2021 Jul 13 (Print Publication: 2021). |
| Publication Type: | Journal Article |
| Language: | English |
| Journal Info: | Publisher: Caltech Library Country of Publication: United States NLM ID: 101759238 Publication Model: eCollection Cited Medium: Internet ISSN: 2578-9430 (Electronic) Linking ISSN: 25789430 NLM ISO Abbreviation: MicroPubl Biol Subsets: PubMed not MEDLINE |
| Imprint Name(s): | Original Publication: Pasadena, CA : Caltech Library, [2016]- |
| Abstract: | Genetic screens are used to identify genes involved in specific biological processes. An EMS mutagenesis screen in Drosophila melanogaster identified growth control phenotypes in the developing eye. One mutant line from this screen, H.3.2, was phenotypically characterized using the FLP/FRT system and genetically mapped by complementation analysis and genomic sequencing by undergraduate students participating in the multi-institution Fly-CURE consortium. H.3.2 was found to have a nonsense mutation in short stop (shot), anortholog of the mammalian spectraplakin dystonin (DST). shot and DST are involved in cytoskeletal organization and play roles during cell growth and proliferation.; (Copyright: © 2021 by the authors.) |
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| Grant Information: | R15 AG074113 United States AG NIA NIH HHS; R15 AR070505 United States AR NIAMS NIH HHS |
| Entry Date(s): | Date Created: 20210719 Latest Revision: 20220716 |
| Update Code: | 20260130 |
| PubMed Central ID: | PMC8278230 |
| DOI: | 10.17912/micropub.biology.000418 |
| PMID: | 34278244 |
| Database: | MEDLINE |
Journal Article