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Bioconversion of Lignocellulosic Materials with the Contribution of a Multifunctional GH78 Glycoside Hydrolase from Xylaria polymorpha to Release Aromatic Fragments and Carbohydrates.

Title: Bioconversion of Lignocellulosic Materials with the Contribution of a Multifunctional GH78 Glycoside Hydrolase from Xylaria polymorpha to Release Aromatic Fragments and Carbohydrates.
Authors: Liers C; InternInternational Graduate School of Zittau (IHI Zittau), Dresden University of Technology, D-03583 Zittau, Germanyational Graduate School of Zittau (IHI Zittau), Dresden University of Technology, D-03583 Zittau, Germany.; Ullrich R; InternInternational Graduate School of Zittau (IHI Zittau), Dresden University of Technology, D-03583 Zittau, Germanyational Graduate School of Zittau (IHI Zittau), Dresden University of Technology, D-03583 Zittau, Germany.; Kellner H; InternInternational Graduate School of Zittau (IHI Zittau), Dresden University of Technology, D-03583 Zittau, Germanyational Graduate School of Zittau (IHI Zittau), Dresden University of Technology, D-03583 Zittau, Germany.; Chi DH; DeDepartment of Cellular and Molecular Anatomy, Hamamatsu University School of Medicine, Hamamatsu, Shizuoka 431-3192, Japanpartment of Cellular & Molecular Anatomy, Hamamatsu University School of Medicine, Hamamatsu, Shizuoka 431-3192, Japan.; Quynh DT; Institute of Natural Products Chemistry, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet, Hanoi, Vietnam.; Graduate University of Science and Technology, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet, Hanoi, Vietnam.; Luyen ND; Institute of Natural Products Chemistry, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet, Hanoi, Vietnam.; Graduate University of Science and Technology, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet, Hanoi, Vietnam.; Huong LM; Institute of Natural Products Chemistry, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet, Hanoi, Vietnam.; Graduate University of Science and Technology, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet, Hanoi, Vietnam.; Hofrichter M; InternInternational Graduate School of Zittau (IHI Zittau), Dresden University of Technology, D-03583 Zittau, Germanyational Graduate School of Zittau (IHI Zittau), Dresden University of Technology, D-03583 Zittau, Germany.; Nghi DH; Institute of Natural Products Chemistry, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet, Hanoi, Vietnam.; Graduate University of Science and Technology, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet, Hanoi, Vietnam.
Source: Journal of microbiology and biotechnology [J Microbiol Biotechnol] 2021 Oct 28; Vol. 31 (10), pp. 1438-1445.
Publication Type: Journal Article
Language: English
Journal Info: Publisher: Korean Society for Microbiology and Biotechnology Country of Publication: Korea (South) NLM ID: 9431852 Publication Model: Print Cited Medium: Internet ISSN: 1738-8872 (Electronic) Linking ISSN: 10177825 NLM ISO Abbreviation: J Microbiol Biotechnol Subsets: MEDLINE
Imprint Name(s): Publication: 2002- : Seoul : Korean Society for Microbiology and Biotechnology; Original Publication: Seoul : Korean Society for Applied Microbiology, 1991-2001.
MeSH Terms: Carbohydrate Metabolism*; Ascomycota/*enzymology ; Glycoside Hydrolases/*metabolism ; Lignin/*metabolism; Fungal Proteins/metabolism ; Arabinose ; Galactose ; Glucose ; Mannose ; Methanol ; Plant Stems ; Wood ; Xylose
Abstract: A bifunctional glycoside hydrolase GH78 from the ascomycete Xylaria polymorpha (XpoGH78) possesses catalytic versatility towards both glycosides and esters, which may be advantageous for the efficient degradation of the plant cell-wall complex that contains both diverse sugar residues and esterified structures. The contribution of XpoGH78 to the conversion of lignocellulosic materials without any chemical pretreatment to release the water-soluble aromatic fragments, carbohydrates, and methanol was studied. The disintegrating effect of enzymatic lignocellulose treatment can be significantly improved by using different kinds of hydrolases and phenoloxidases. The considerable changes in low (3 kDa), medium (30 kDa), and high (> 200 kDa) aromatic fragments were observed after the treatment with XpoGH78 alone or with this potent cocktail. Synergistic conversion of rape straw also resulted in a release of 17.3 mg of total carbohydrates (e.g., arabinose, galactose, glucose, mannose, xylose) per gram of substrate after incubating for 72 h. Moreover, the treatment of rape straw with XpoGH78 led to a marginal methanol release of approximately 17 μg/g and improved to 270 μg/g by cooperation with the above accessory enzymes. In the case of beech wood conversion, the combined catalysis by XpoGH78 and laccase caused an effect comparable with that of fungal strain X. polymorpha in woody cultures concerning the liberation of aromatic lignocellulose fragments.
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Contributed Indexing: Keywords: Glycoside hydrolase; Xylaria polymorpha; ascomycetous fungus; enzyme cocktail; lignocelluloses
Substance Nomenclature: 0 (Fungal Proteins); 11132-73-3 (lignocellulose); 9005-53-2 (Lignin); A1TA934AKO (Xylose); B40ROO395Z (Arabinose); EC 3.2.1.- (Glycoside Hydrolases); IY9XDZ35W2 (Glucose); PHA4727WTP (Mannose); X2RN3Q8DNE (Galactose); Y4S76JWI15 (Methanol)
SCR Organism: Xylaria polymorpha
Entry Date(s): Date Created: 20210819 Date Completed: 20211217 Latest Revision: 20240908
Update Code: 20260130
PubMed Central ID: PMC9705965
DOI: 10.4014/jmb.2106.06053
PMID: 34409952
Database: MEDLINE

Journal Article