Efficacy of personal pharmacogenomic testing as an educational tool in the pharmacy curriculum: A nonblinded, randomized controlled trial.
| Title: | Efficacy of personal pharmacogenomic testing as an educational tool in the pharmacy curriculum: A nonblinded, randomized controlled trial. |
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| Authors: | Grace C; Department of Pharmacy Practice and Science, University of Arizona College of Pharmacy, Tucson, Arizona, USA.; Larriva MM; Department of Pharmacy Practice and Science, University of Arizona College of Pharmacy, Tucson, Arizona, USA.; Arizona Oncology, Tucson, Arizona, USA.; Steiner HE; Department of Pharmacy Practice and Science, University of Arizona College of Pharmacy, Tucson, Arizona, USA.; Marupuru S; Department of Pharmacy Practice and Science, University of Arizona College of Pharmacy, Tucson, Arizona, USA.; Campbell PJ; Department of Pharmacy Practice and Science, University of Arizona College of Pharmacy, Tucson, Arizona, USA.; Patterson H; Department of Pharmacy Practice and Science, University of Arizona College of Pharmacy, Tucson, Arizona, USA.; Cropp CD; Department of Pharmaceutical, Social and Administrative Sciences, Samford University McWhorter School of Pharmacy, Birmingham, Alabama, USA.; Quinn D; Department of Pharmacy Practice and Science, University of Arizona College of Pharmacy, Tucson, Arizona, USA.; Department of Obstetrics and Gynecology, University of Arizona College of Medicine-Tucson, Tucson, Arizona, USA.; Klimecki W; College of Veterinary Medicine, University of Arizona, Tucson, Arizona, USA.; Department of Pharmacology and Toxicology, University of Arizona College of Pharmacy, Tucson, Arizona, USA.; Nix DE; Department of Pharmacy Practice and Science, University of Arizona College of Pharmacy, Tucson, Arizona, USA.; Warholak T; Department of Pharmacy Practice and Science, University of Arizona College of Pharmacy, Tucson, Arizona, USA.; Karnes JH; Department of Pharmacy Practice and Science, University of Arizona College of Pharmacy, Tucson, Arizona, USA.; Department of Pharmacology and Toxicology, University of Arizona College of Pharmacy, Tucson, Arizona, USA.; Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, Tennessee, USA. |
| Source: | Clinical and translational science [Clin Transl Sci] 2021 Nov; Vol. 14 (6), pp. 2532-2543. Date of Electronic Publication: 2021 Aug 25. |
| Publication Type: | Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| Language: | English |
| Journal Info: | Publisher: WileyBlackwell Pub Country of Publication: United States NLM ID: 101474067 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1752-8062 (Electronic) Linking ISSN: 17528054 NLM ISO Abbreviation: Clin Transl Sci Subsets: MEDLINE |
| Imprint Name(s): | Original Publication: Malden, MA : WileyBlackwell Pub., 2008- |
| MeSH Terms: | Curriculum* ; Education, Pharmacy* ; Pharmacogenomic Testing*; Adult ; Female ; Genotyping Techniques ; Humans ; Male ; Surveys and Questionnaires ; Young Adult |
| Abstract: | Personal genomic educational testing (PGET) has been suggested as a strategy to improve student learning for pharmacogenomics (PGx), but no randomized studies have evaluated PGET's educational benefit. We investigated the effect of PGET on student knowledge, comfort, and attitudes related to PGx in a nonblinded, randomized controlled trial. Consenting participants were randomized to receive PGET or no PGET (NPGET) during 4 subsequent years of a PGx course. All participants completed a pre-survey and post-survey designed to assess (1) PGx knowledge, (2) comfort with PGx patient education and clinical skills, and (3) attitudes toward PGx. Instructors were blinded to PGET assignment. The Wilcoxon Rank Sum test was used to compare pre-survey and post-survey PGx knowledge, comfort, and attitudes. No differences in baseline characteristics were observed between PGET (n = 117) and NPGET (n = 116) participants. Among all participants, significant improvement was observed in PGx knowledge (mean 57% vs. 39% correct responses; p |
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| Grant Information: | K01 HL143137 United States HL NHLBI NIH HHS |
| Entry Date(s): | Date Created: 20210825 Date Completed: 20220209 Latest Revision: 20220209 |
| Update Code: | 20260130 |
| PubMed Central ID: | PMC8604226 |
| DOI: | 10.1111/cts.13121 |
| PMID: | 34431601 |
| Database: | MEDLINE |
Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't