Seroprevalence of the SARS-CoV-2 antibody in healthcare workers: a multicentre cross-sectional study in 10 Colombian cities.
| Title: | Seroprevalence of the SARS-CoV-2 antibody in healthcare workers: a multicentre cross-sectional study in 10 Colombian cities. |
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| Authors: | Malagón-Rojas JN; Doctorado en Salud Pública, El Bosque University Faculty of Medicine, Bogota, Colombia jnmalagon@unbosque.edu.co.; Grupo de investigación en Salud Ambiental y Laboral, Instituto Nacional de Salud, Bogotá, Colombia.; Mercado-Reyes M; Research Directorate, National Institute of Health, Bogota, Colombia.; Toloza-Pérez YG; Grupo de investigación en Salud Ambiental y Laboral, Instituto Nacional de Salud, Bogotá, Colombia.; Parra Barrera EL; Grupo de investigación en Salud Ambiental y Laboral, Instituto Nacional de Salud, Bogotá, Colombia.; Palma M; Grupo de investigación en Salud Ambiental y Laboral, Instituto Nacional de Salud, Bogotá, Colombia.; Muñoz E; Faculty of Nursing, National University of Colombia, Bogota, Colombia.; López R; Grupo de investigación en Salud Ambiental y Laboral, Instituto Nacional de Salud, Bogotá, Colombia.; Almentero J; Grupo de investigación en Salud Ambiental y Laboral, Instituto Nacional de Salud, Bogotá, Colombia.; Rubio VV; Research Directorate, National Institute of Health, Bogota, Colombia.; Ibáñez E; El Bosque University Faculty of Medicine, Bogota, Colombia.; Téllez E; Grupo de investigación en Salud Ambiental y Laboral, Instituto Nacional de Salud, Bogotá, Colombia.; Red de Investigación, Innovación y Desarrollo en Seguridad y Salud en el Trabajo, Bogota, Colombia.; Delgado-Murcia LG; Immunotoxicology Research Group, National University of Colombia-Bogota, Bogota, Colombia.; Jimenez CP; National Open and Distance University, Bucaramanga, Colombia.; Red de Investigación, Innovación y Desarrollo en Seguridad y Salud en el Trabajo, Bogotá, Colombia.; Viasus-Pérez D; School of Medicine, Universidad del Norte, Barranquilla, Colombia.; Galindo M; Research Directorate, National Institute of Health, Bogota, Colombia.; Lagos L; Grupo de investigación en Salud Ambiental y Laboral, Instituto Nacional de Salud, Bogotá, Colombia. |
| Corporate Authors: | Interinstitutional Support Group |
| Source: | Occupational and environmental medicine [Occup Environ Med] 2022 Jun; Vol. 79 (6), pp. 388-395. Date of Electronic Publication: 2021 Nov 05. |
| Publication Type: | Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't |
| Language: | English |
| Journal Info: | Publisher: BMJ Pub. Group Country of Publication: England NLM ID: 9422759 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1470-7926 (Electronic) Linking ISSN: 13510711 NLM ISO Abbreviation: Occup Environ Med Subsets: MEDLINE |
| Imprint Name(s): | Original Publication: London : BMJ Pub. Group, c1994- |
| MeSH Terms: | COVID-19*/epidemiology ; SARS-CoV-2*; Cities/epidemiology ; Colombia/epidemiology ; Antibodies, Viral ; Bayes Theorem ; Cross-Sectional Studies ; Health Personnel ; Humans ; Immunoglobulin G ; Seroepidemiologic Studies |
| Abstract: | Background: Healthcare workers are at increased risk of infection due to occupational exposure to SARS-CoV-2-infected patients. The objective of this study was to determine the seroprevalence of SARS-CoV-2 in healthcare workers in Colombia.; Methods: This study is a cross-sectional study focused on estimating the seroprevalence of SARS-CoV-2 antibodies in healthcare workers from 65 hospitals in 10 cities in Colombia during the second semester of 2020. The seroprevalence was determined using an automated immunoassay (Abbott SARS-CoV-2 CLIA IgG). The study included a survey to establish the sociodemographic variables and the risk of infection. A multivariate model was used to evaluate the association between the results of seroprevalence and risk factors.; Results: The global seroprevalence of antibodies against SARS-CoV-2 was 35% (95% Bayesian CI 33% to 37%). All the personnel reported the use of protective equipment. General services personnel and nurses presented the highest ratios of seroprevalence among the healthcare workers. Low socioeconomic strata have shown a strong association with seropositivity.; Conclusion: This study estimates the prevalence of SARS-CoV-2 infection among healthcare workers. Even though all the personnel reported the use of protective equipment, the seroprevalence in the general services personnel and nurses was high. Also, a significant difference by cities was observed.; (© Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.) |
| Competing Interests: | Competing interests: None declared. |
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| Contributed Indexing: | Investigator: M Weisner; G Puerto; L Muñoz-Galindo; MT Herrera; J Reales; E Cárdenas-Villamil; J Ortíz; L Ovideo; L Serrano; S Botero; JF Bedoya; H Rodríguez-Perea; N Celis-Cruz; Keywords: COVID-19; cross-sectional studies; health personnel; occupational health; public health |
| Substance Nomenclature: | 0 (Antibodies, Viral); 0 (Immunoglobulin G) |
| Entry Date(s): | Date Created: 20211106 Date Completed: 20220517 Latest Revision: 20260127 |
| Update Code: | 20260130 |
| PubMed Central ID: | PMC8577941 |
| DOI: | 10.1136/oemed-2021-107487 |
| PMID: | 34740981 |
| Database: | MEDLINE |
Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't