[Lymphocyte subpopulations in sensitization and specific immunotherapy in an experiment. Lymphocyte subpopulations in the specific immunotherapy of microbial allergy and subsequent heterologous pollen sensitization].
| Title: | [Lymphocyte subpopulations in sensitization and specific immunotherapy in an experiment. Lymphocyte subpopulations in the specific immunotherapy of microbial allergy and subsequent heterologous pollen sensitization]. |
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| Transliterated Title: | Subpopuliatsii limfotsitov pri sensibilizatsii i spetsificheskoĭ immunoterapii v éksperimente. Subpopuliatsii limfotsitov pri spetsificheskoĭ immunoterapii mikrobnoĭ allergii i posleduiushcheĭ geterologichnoĭ pyl'tsevoĭ sensibilizatsii. |
| Authors: | Nugmanova DS; Nugmanova ZhS; Sukhodova GS; Beklemishev ND; Bul'vakhter IaL |
| Source: | Zhurnal mikrobiologii, epidemiologii i immunobiologii [Zh Mikrobiol Epidemiol Immunobiol] 1986 Sep (9), pp. 53-7. |
| Publication Type: | Comparative Study; English Abstract; Journal Article |
| Language: | Russian |
| Journal Info: | Publisher: FBUN T︠S︡NII Ėpidemiologii Rospotrebnadzora Country of Publication: Russia (Federation) NLM ID: 0415217 Publication Model: Print Cited Medium: Print ISSN: 0372-9311 (Print) Linking ISSN: 03729311 NLM ISO Abbreviation: Zh Mikrobiol Epidemiol Immunobiol Subsets: MEDLINE |
| Imprint Name(s): | Publication: : Moskva : FBUN T︠S︡NII Ėpidemiologii Rospotrebnadzora; Original Publication: Moskva : Izd-vo "Medit︠s︡ina" |
| MeSH Terms: | Immunotherapy*; B-Lymphocytes/*immunology ; Hypersensitivity, Delayed/*therapy ; Hypersensitivity, Immediate/*therapy ; Pollen/*immunology ; Staphylococcus aureus/*immunology ; T-Lymphocytes/*immunology; Allergens/administration & dosage ; Desensitization, Immunologic/methods ; Hypersensitivity, Delayed/immunology ; Hypersensitivity, Immediate/immunology ; Animals ; Guinea Pigs ; Immunization ; Rosette Formation |
| Abstract: | The influence exerted by the specific immunotherapy (SIT) of delayed hypersensitivity (DH) to staphylococci and subsequent sensitization with tarragon pollen on the level of immunocompetent cells in the blood and lymphoid organs of guinea pigs was studied. On the whole, SIT normalized the characteristics of T- and B-lymphocytes, altered as the result of experimentally induced DH: the content of T-cells in the peripheral blood and the lymph nodes increased, while the number of B-cells in the blood and T gamma-suppressors increased. The subsequent heterologous sensitization with pollen abolished the effect of SIT, inducing the general decrease of the level of T gamma-lymphocytes and enhancing the number of T-lymphocytes in the lymph nodes. |
| Substance Nomenclature: | 0 (Allergens) |
| Entry Date(s): | Date Created: 19860901 Date Completed: 19861229 Latest Revision: 20200716 |
| Update Code: | 20260130 |
| PMID: | 3491480 |
| Database: | MEDLINE |
Comparative Study; English Abstract; Journal Article