Effect of Femtosecond Laser Cataract Surgery on Peripapillary Retinal Nerve Fiber Layer Thickness.
| Title: | Effect of Femtosecond Laser Cataract Surgery on Peripapillary Retinal Nerve Fiber Layer Thickness. |
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| Authors: | Geyer O; Department of Ophthalmology Carmel Medical Center, Affiliated to the Rapaport Faculty of Medicine, The Technion.; Ben-Shaul O; Department of Ophthalmology Carmel Medical Center, Affiliated to the Rapaport Faculty of Medicine, The Technion.; Lux C; Department of Ophthalmology Carmel Medical Center, Affiliated to the Rapaport Faculty of Medicine, The Technion.; Schwartz S; Department of Ophthalmology Carmel Medical Center, Affiliated to the Rapaport Faculty of Medicine, The Technion.; Podkovyrin O; Department of Ophthalmology Carmel Medical Center, Affiliated to the Rapaport Faculty of Medicine, The Technion.; Stein N; Community Medicine and Epidemiology, Carmel Medical Center, Haifa, Israel.; Lavi I; Community Medicine and Epidemiology, Carmel Medical Center, Haifa, Israel.; Mathalone N; Department of Ophthalmology Carmel Medical Center, Affiliated to the Rapaport Faculty of Medicine, The Technion. |
| Source: | Journal of glaucoma [J Glaucoma] 2022 May 01; Vol. 31 (5), pp. 340-345. Date of Electronic Publication: 2022 Mar 18. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Language: | English |
| Journal Info: | Publisher: Wolters Kluwer Health, Inc Country of Publication: United States NLM ID: 9300903 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1536-481X (Electronic) Linking ISSN: 10570829 NLM ISO Abbreviation: J Glaucoma Subsets: MEDLINE |
| Imprint Name(s): | Publication: : Philadelphia, PA : Wolters Kluwer Health, Inc.; Original Publication: New York, N.Y. : Raven Press, c1992- |
| MeSH Terms: | Cataract* ; Nerve Fibers*; Humans ; Intraocular Pressure ; Lasers ; Prospective Studies ; Retinal Ganglion Cells |
| Abstract: | Prcis: Femtosecond laser-assisted cataract surgery (FLACS) may cause thinning of the peripapillary retinal nerve fiber layer (pRNFL) in healthy eyes.; Purpose: This prospective cohort study aimed to compare changes of pRNFL after FLACS using a liquid patient interface and conventional phacoemulsification cataract surgery (CPCS).; Patients and Methods: Included were 261 eyes (261 patients) with age-related cataracts and no ocular diseases scheduled either for FLACS (222 eyes) or CPCS (39 eyes). FLACS was performed using a Ziemer LDV Z8 laser. Average and quadrant pRNFL thickness was measured using optical coherence tomography before surgery and at 1, 3, and 6 months postoperatively. Postoperative changes in pRNFL thickness were compared within and between groups.; Results: Mean quadrant and average pRNFL thicknesses significantly increased after both surgeries (P0.05). FLACS eyes showed a significant and stable decrease of average pRNFL thickness (P=0.057) and a gradual decrease in pRNFL thickness of all quadrants (P≤0.018). CPCS eyes showed an initial increase of pRNFL thickness, followed by a decrease only in the nasal quadrant and average pRNFL. Preoperative pRNFL thickness was associated with thinning of the temporal quadrant (P=0.04).; Conclusions: Both FLACS and CPCS demonstrated pRNFL thinning in some healthy eyes. Although the higher rate of pRNFL thinning after FLACS compared with CPCS lacked statistical significance, a consistent decrease in pRNFL thickness occurred in all quadrants and average pRNFL of FLACS eyes, suggesting that FLACS may lead to pRNFL thinning. Eyes with thinner preoperative pRNFL may be prone to temporal quadrant thinning after FLACS.; (Copyright © 2022 Wolters Kluwer Health, Inc. All rights reserved.) |
| Competing Interests: | Disclosure: The authors declare no conflict of interest. |
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| Entry Date(s): | Date Created: 20220318 Date Completed: 20220429 Latest Revision: 20230928 |
| Update Code: | 20260130 |
| DOI: | 10.1097/IJG.0000000000002014 |
| PMID: | 35302537 |
| Database: | MEDLINE |
Journal Article; Research Support, Non-U.S. Gov't