Characterizing Alcohol Expectancies in the ABCD Study: Associations with Sociodemographic Factors, the Immediate Social Environment, and Genetic Propensities.
| Title: | Characterizing Alcohol Expectancies in the ABCD Study: Associations with Sociodemographic Factors, the Immediate Social Environment, and Genetic Propensities. |
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| Authors: | Johnson EC; Department of Psychiatry, Washington University School of Medicine, 660 S. Euclid, CB 8134, St. Louis, MO, 63110, USA. emma.c.johnson@wustl.edu.; Paul SE; Department of Psychological and Brain Sciences, Washington University in Saint Louis, St. Louis, MO, USA.; Baranger DAA; Department of Psychological and Brain Sciences, Washington University in Saint Louis, St. Louis, MO, USA.; Hatoum AS; Department of Psychiatry, Washington University School of Medicine, 660 S. Euclid, CB 8134, St. Louis, MO, 63110, USA.; Department of Psychological and Brain Sciences, Washington University in Saint Louis, St. Louis, MO, USA.; Colbert SMC; Department of Psychiatry, Washington University School of Medicine, 660 S. Euclid, CB 8134, St. Louis, MO, 63110, USA.; Lin S; Department of Psychological and Brain Sciences, Washington University in Saint Louis, St. Louis, MO, USA.; Wolff R; Department of Psychological and Brain Sciences, Washington University in Saint Louis, St. Louis, MO, USA.; Gorelik AJ; Department of Psychological and Brain Sciences, Washington University in Saint Louis, St. Louis, MO, USA.; Hansen I; Department of Psychological and Brain Sciences, Washington University in Saint Louis, St. Louis, MO, USA.; Karcher NR; Department of Psychiatry, Washington University School of Medicine, 660 S. Euclid, CB 8134, St. Louis, MO, 63110, USA.; Bogdan R; Department of Psychological and Brain Sciences, Washington University in Saint Louis, St. Louis, MO, USA.; Agrawal A; Department of Psychiatry, Washington University School of Medicine, 660 S. Euclid, CB 8134, St. Louis, MO, 63110, USA. |
| Source: | Behavior genetics [Behav Genet] 2023 May; Vol. 53 (3), pp. 265-278. Date of Electronic Publication: 2023 Jan 20. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S. |
| Language: | English |
| Journal Info: | Publisher: Kluwer Academic/Plenum Publishers Country of Publication: United States NLM ID: 0251711 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-3297 (Electronic) Linking ISSN: 00018244 NLM ISO Abbreviation: Behav Genet Subsets: MEDLINE |
| Imprint Name(s): | Publication: 1999- : New York : Kluwer Academic/Plenum Publishers; Original Publication: Westport, Conn., Greenwood Periodicals. |
| MeSH Terms: | Underage Drinking*/psychology ; Sociodemographic Factors* ; Social Environment*; Humans ; Child ; Adolescent ; Genetic Predisposition to Disease ; Male ; Female ; Socioeconomic Factors ; Adverse Childhood Experiences |
| Abstract: | Alcohol expectancies (AEs) are associated with likelihood of alcohol initiation and subsequent alcohol use disorders. It is unclear whether genetic predisposition to alcohol use and/or related traits contributes to shaping how one expects to feel when drinking alcohol. We used the Adolescent Brain Cognitive Development study to examine associations between genetic propensities (i.e., polygenic risk for problematic alcohol use, depression, risk-taking), sociodemographic factors (i.e., parent income), and the immediate social environment (i.e., peer use and disapproval toward alcohol) and positive and negative AEs in alcohol-naïve children (max analytic N = 5,352). Mixed-effect regression models showed that age, parental education, importance of the child's religious beliefs, adverse childhood experiences, and peer disapproval of alcohol use were associated with positive and/or negative AEs, to varying degrees. Overall, our results suggest several familial and psychosocial predictors of AEs but little evidence of contributions from polygenic liability to problematic alcohol use or related phenotypes.; (© 2023. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.) |
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| Grant Information: | U24 DA041147 United States DA NIDA NIH HHS; U01 DA041120 United States DA NIDA NIH HHS; R01 DA054750 United States DA NIDA NIH HHS; U01 DA041093 United States DA NIDA NIH HHS; U24 DA041123 United States DA NIDA NIH HHS; F31 AA029934 United States AA NIAAA NIH HHS; U01 DA041156 United States DA NIDA NIH HHS; K01 DA051759 United States DA NIDA NIH HHS; K01 AA030083 United States AA NIAAA NIH HHS; U01 DA041025 United States DA NIDA NIH HHS; U01 DA041089 United States DA NIDA NIH HHS; U01 DA041117 United States DA NIDA NIH HHS; U01 DA041148 United States DA NIDA NIH HHS; U01 DA041174 United States DA NIDA NIH HHS; U01 DA041134 United States DA NIDA NIH HHS; U01 DA041022 United States DA NIDA NIH HHS; U01 DA041106 United States DA NIDA NIH HHS; T32 DA007261 United States DA NIDA NIH HHS; U01 DA041028 United States DA NIDA NIH HHS; U01 DA041048 United States DA NIDA NIH HHS |
| Contributed Indexing: | Keywords: Adverse childhood experiences; Alcohol expectancies; Educational attainment; Peer deviance; Polygenic risk scores; Religiosity |
| Entry Date(s): | Date Created: 20230120 Date Completed: 20230504 Latest Revision: 20250801 |
| Update Code: | 20260130 |
| PubMed Central ID: | PMC10159951 |
| DOI: | 10.1007/s10519-023-10133-2 |
| PMID: | 36662388 |
| Database: | MEDLINE |
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.