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Effectiveness of Ramadan diurnal intermittent fasting and concurrent training in the management of obesity: is the combination worth the weight?

Title: Effectiveness of Ramadan diurnal intermittent fasting and concurrent training in the management of obesity: is the combination worth the weight?
Authors: Maaloul R; High Institute of Sport and Physical Education of Sfax, University of Sfax, Tunisia; Research Laboratory, Molecular Bases of Human Pathology, LR19ES13, Faculty of Medicine, University of Sfax, Tunisia.; Marzougui H; High Institute of Sport and Physical Education of Sfax, University of Sfax, Tunisia; Research Laboratory, Molecular Bases of Human Pathology, LR19ES13, Faculty of Medicine, University of Sfax, Tunisia.; Ben Dhia I; High Institute of Sport and Physical Education of Sfax, University of Sfax, Tunisia; Research Laboratory of Evaluation and Management of Musculoskeletal System Pathologies, LR20ES09, University of Sfax, Tunisia.; Ghroubi S; Research Laboratory of Evaluation and Management of Musculoskeletal System Pathologies, LR20ES09, University of Sfax, Tunisia.; Tagougui S; Montreal Clinical Research Institute, Montreal, Canada; Université de Lille, Université d'Artois, Université du Littoral Côte d'Opale, ULR 7369-URePSSS-Unité de Recherche Pluridisciplinaire Sport Santé Société, Lille, France.; Kallel C; Hematology laboratory, CHU Habib Bourguiba, Sfax, Tunisia.; Driss T; Interdisciplinary Laboratory in Neurosciences, Physiology and Psychology: Physical Activity, Health and Learning (LINP2), UFR STAPS, UPL, Paris Nanterre, Nanterre, France.; Elleuch MH; Research Laboratory of Evaluation and Management of Musculoskeletal System Pathologies, LR20ES09, University of Sfax, Tunisia.; Ayadi F; Research Laboratory, Molecular Bases of Human Pathology, LR19ES13, Faculty of Medicine, University of Sfax, Tunisia.; Turki M; Research Laboratory, Molecular Bases of Human Pathology, LR19ES13, Faculty of Medicine, University of Sfax, Tunisia.; Hammouda O; Research Laboratory, Molecular Bases of Human Pathology, LR19ES13, Faculty of Medicine, University of Sfax, Tunisia; Interdisciplinary Laboratory in Neurosciences, Physiology and Psychology: Physical Activity, Health and Learning (LINP2), UFR STAPS, UPL, Paris Nanterre, Nanterre, France. Electronic address: hammouda.o@parisnanterre.fr.
Source: Nutrition, metabolism, and cardiovascular diseases : NMCD [Nutr Metab Cardiovasc Dis] 2023 Mar; Vol. 33 (3), pp. 659-666. Date of Electronic Publication: 2022 Dec 20.
Publication Type: Randomized Controlled Trial; Journal Article
Language: English
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 9111474 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1590-3729 (Electronic) Linking ISSN: 09394753 NLM ISO Abbreviation: Nutr Metab Cardiovasc Dis Subsets: MEDLINE
Imprint Name(s): Publication: 2005- : Amsterdam : Elsevier; Original Publication: [Heidelberg] : Springer International, c1991-
MeSH Terms: Blood Glucose*/metabolism ; Intermittent Fasting*; Obesity/diagnosis ; Obesity/therapy ; Biomarkers/metabolism ; Inflammation/diagnosis ; Male ; Humans ; Young Adult ; Adult ; Body Composition ; Lipids
Abstract: Background and Aims: We investigated, in men with obesity, the efficacy of the combination of two strategies (Ramadan diurnal intermittent fasting 'RDIF' strategy vs RDIF plus concurrent training program 'RDIF-CT' strategy) known for their positive impact on body composition and then we explored the possible impact on metabolic and inflammatory biomarkers.; Methods and Results: Twenty obese men, age: 31.8 ± 7.05 years, BMI: 33.1 ± 4.2 kg m-2, performing regularly RDIF, were randomized into two groups: RDIF-CT (n = 10) and RDIF without training (RDIF-NCT) (n = 10). The RDIF-CT group participated in High intensity interval training (HIIT) program combined with resistance exercises for 4 weeks. Body composition, blood glucose, lipid profile, liver biomarkers and inflammation were assessed before and after 4-week RDIF. Both groups showed a significant decrease in weight, fat mass (FM), fat percentage (Fat%) and waist circumference (WC) and an improvement in blood glucose, lipid profile and inflammation. Fat free mass decreased significantly in RDIF-NCT (p 
Competing Interests: Declaration of competing interest The authors declare no conflict of interest.
Contributed Indexing: Keywords: Concurrent exercise training; HIIT; Intermittent fasting; Obesity; Time restricted eating
Substance Nomenclature: 0 (Blood Glucose); 0 (Lipids); 0 (Biomarkers)
Entry Date(s): Date Created: 20230129 Date Completed: 20230223 Latest Revision: 20230301
Update Code: 20260130
DOI: 10.1016/j.numecd.2022.12.004
PMID: 36710112
Database: MEDLINE

Randomized Controlled Trial; Journal Article