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Left ventricular summit premature ventricular contractions treated by venous ethanol infusion: Scar assessment by magnetic resonance imaging.

Title: Left ventricular summit premature ventricular contractions treated by venous ethanol infusion: Scar assessment by magnetic resonance imaging.
Authors: Limite LR; Service de Cardiologie, Hôpital Privé Les Franciscaines, ELSAN, Nîmes, France.; Laborie G; Service de Cardiologie, Hôpital Privé Les Franciscaines, ELSAN, Nîmes, France.; Constantin J; Biosense Webster France, Johnson & Johnson, Issy les Moulineaux, France.; Maubon A; Service de Radiologie, Hôpital Privé Les Franciscaines, ELSAN, Nîmes, France.; Arcari L; Cardiology Unit, Madre Giuseppina Vannini Hospital, Rome, Italy.; Hebert C; Biosense Webster France, Johnson & Johnson, Issy les Moulineaux, France.; Bortone A; Service de Cardiologie, Hôpital Privé Les Franciscaines, ELSAN, Nîmes, France.
Source: Pacing and clinical electrophysiology : PACE [Pacing Clin Electrophysiol] 2023 Oct; Vol. 46 (10), pp. 1235-1238. Date of Electronic Publication: 2023 Mar 12.
Publication Type: Case Reports; Journal Article
Language: English
Journal Info: Publisher: Futura Pub. Co Country of Publication: United States NLM ID: 7803944 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1540-8159 (Electronic) Linking ISSN: 01478389 NLM ISO Abbreviation: Pacing Clin Electrophysiol Subsets: MEDLINE
Imprint Name(s): Original Publication: Mount Kisco, N. Y. : Futura Pub. Co., c1978-
MeSH Terms: Ventricular Premature Complexes*/surgery ; Catheter Ablation*/methods; Cicatrix/surgery ; Female ; Humans ; Adult ; Ethanol ; Magnetic Resonance Imaging ; Treatment Outcome
Abstract: Left ventricular (LV) summit premature ventricular contractions (PVCs) are often unresponsive to radiofrequency (RF) ablation. Retrograde venous ethanol infusion (RVEI) can be a valuable alternative in this scenario. A 43-year-old woman without structural heart disease presented with LV summit PVCs unresponsive to RF ablation because of their deep-seated origin. Unipolar pace mapping performed through a wire inserted into a branch of the distal great cardiac vein (GCV) demonstrated 12/12 concordance with the clinical PVCs thus indicating close proximity to PVCs' origin. RVEI abolished the PVCs without complications. Subsequently, magnetic resonance imaging (MRI) evidenced an intramural myocardial scar produced by ethanol ablation. In conclusion, RVEI effectively and safely treated PVC arising from a deep site in the LVS. The scar provoked by chemical damage was well characterized by MRI imaging.; (© 2023 Wiley Periodicals LLC.)
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Contributed Indexing: Keywords: deep substrate; late gadolinium enhancement; left ventricular summit; premature ventricular contractions; retrograde coronary venous ethanol infusion
Substance Nomenclature: 3K9958V90M (Ethanol)
Entry Date(s): Date Created: 20230222 Date Completed: 20231023 Latest Revision: 20231025
Update Code: 20260130
DOI: 10.1111/pace.14680
PMID: 36811180
Database: MEDLINE

Case Reports; Journal Article