Age distribution of dengue cases in southern Vietnam from 2000 to 2015.
| Title: | Age distribution of dengue cases in southern Vietnam from 2000 to 2015. |
|---|---|
| Authors: | Taurel AF; Sanofi, Singapore, Republic of Singapore.; Luong CQ; Pasteur Institute Ho Chi Minh City, Ho Chi Minh City, Vietnam.; Nguyen TTT; Pasteur Institute Ho Chi Minh City, Ho Chi Minh City, Vietnam.; Do KQ; Pasteur Institute Ho Chi Minh City, Ho Chi Minh City, Vietnam.; Diep TH; Pasteur Institute Ho Chi Minh City, Ho Chi Minh City, Vietnam.; Nguyen TV; Pasteur Institute Ho Chi Minh City, Ho Chi Minh City, Vietnam.; Cao MT; Pasteur Institute Ho Chi Minh City, Ho Chi Minh City, Vietnam.; Hoang TND; Pasteur Institute Ho Chi Minh City, Ho Chi Minh City, Vietnam.; Huynh PT; Pasteur Institute Ho Chi Minh City, Ho Chi Minh City, Vietnam.; Huynh TKL; Pasteur Institute Ho Chi Minh City, Ho Chi Minh City, Vietnam.; Le MH; Pasteur Institute Ho Chi Minh City, Ho Chi Minh City, Vietnam.; Nealon J; Sanofi, Lyon, France.; Moureau A; Sanofi, Marcy l'Etoile, France. |
| Source: | PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2023 Feb 24; Vol. 17 (2), pp. e0011137. Date of Electronic Publication: 2023 Feb 24 (Print Publication: 2023). |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Language: | English |
| Journal Info: | Publisher: Public Library of Science Country of Publication: United States NLM ID: 101291488 Publication Model: eCollection Cited Medium: Internet ISSN: 1935-2735 (Electronic) Linking ISSN: 19352727 NLM ISO Abbreviation: PLoS Negl Trop Dis Subsets: MEDLINE |
| Imprint Name(s): | Original Publication: San Francisco, CA : Public Library of Science |
| MeSH Terms: | Dengue*; Vietnam/epidemiology ; Humans ; Aged ; Child, Preschool ; Child ; Adolescent ; Young Adult ; Adult ; Age Distribution ; Retrospective Studies ; Incidence |
| Abstract: | Background: Dengue is the most common vector-borne viral infection. In recent times, an increase in the age of cases with clinical dengue has been reported in the national surveillance system and published literature of Vietnam. This change not only alter the risk of transmission and disease burden in different populations but also will impact for prevention and control strategies. A retrospective study was conducted from 2000 to 2015 in 19 provinces of southern Vietnam to describe the changes in age distribution of dengue cases and circulating serotypes.; Methodology/principal Findings: The study is a time trend analysis of the data aggregated from the database of dengue surveillance system. The database consisted of clinically diagnosed and laboratory-confirmed cases of dengue in southern Vietnam from 2000 to 2015. In the study period, the mean age of dengue cases increased from 12.2 ± 8.8 years old (y/o) to 16.8 ± 13.3 y/o between 2000 and 2015. Majority of severe cases were observed in the age group of 5-9 y/o and 10-14 y/o. Overall, the mortality and case fatality rates (CFR) were lowest during 2010 to 2015, and all four serotypes of dengue were observed.; Conclusions/significance: With the exception of severe form, the age distribution of clinical cases of dengue appears to be shifting towards older age groups. An increase in the mean age of clinical cases of dengue has been observed in southern Vietnam over the past decade, and the highest incidence was observed in age group of 5-14 y/o. All serotypes of dengue were in circulation.; (Copyright: © 2023 Taurel et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.) |
| Competing Interests: | I have read the journal’s policy and the authors of this manuscript have the following competing interests: AM is an employee of Sanofi and may hold shares and/or stock options in the company. A-F T and JN were employees of Sanofi at the time of this study. Rest of authors have no competing interests to disclose. |
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| Entry Date(s): | Date Created: 20230224 Date Completed: 20230310 Latest Revision: 20230328 |
| Update Code: | 20260130 |
| PubMed Central ID: | PMC9994699 |
| DOI: | 10.1371/journal.pntd.0011137 |
| PMID: | 36827445 |
| Database: | MEDLINE |
Journal Article; Research Support, Non-U.S. Gov't