Ultrasound Visualization and Recording of Transient Myocardial Vibrations.
| Title: | Ultrasound Visualization and Recording of Transient Myocardial Vibrations. |
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| Authors: | Moore C; Department of Biomedical Engineering, Duke University, Durham, NC, USA. Electronic address: cooper.moore@duke.edu.; McCrary AW; Department of Pediatrics, Duke University Medical Center, Durham, NC, USA.; LeFevre M; Department of Medicine, Duke University Medical Center, Durham, NC, USA.; Sturgeon GM; Department of Pediatrics, Duke University Medical Center, Durham, NC, USA.; Barker PAC; Department of Pediatrics, Duke University Medical Center, Durham, NC, USA.; von Ramm OT; Department of Biomedical Engineering, Duke University, Durham, NC, USA. |
| Source: | Ultrasound in medicine & biology [Ultrasound Med Biol] 2023 Jun; Vol. 49 (6), pp. 1431-1440. Date of Electronic Publication: 2023 Mar 27. |
| Publication Type: | Journal Article |
| Language: | English |
| Journal Info: | Publisher: Pergamon Press Country of Publication: England NLM ID: 0410553 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-291X (Electronic) Linking ISSN: 03015629 NLM ISO Abbreviation: Ultrasound Med Biol Subsets: MEDLINE |
| Imprint Name(s): | Original Publication: Oxford, New York, Pergamon Press. |
| MeSH Terms: | Echocardiography*/methods ; Amyloidosis*; Humans ; Vibration ; Heart ; Ultrasonography ; Myocardial Contraction ; Ventricular Function, Left |
| Abstract: | Objective: A new visualization and recording method used to assess and quantitate autogenic high-velocity motions in myocardial walls to provide a new description of cardiac function is described.; Methods: The regional motion display (RMD) is based on high-speed difference ultrasound B-mode images and spatiotemporal processing to record propagating events (PEs). Sixteen normal participants and one patient with cardiac amyloidosis were imaged at rates of 500-1000/s using the Duke Phased Array Scanner, T5. RMDs were generated using difference images and spatially integrating these to display velocity as function of time along a cardiac wall.; Results: In normal participants, RMDs revealed four discrete PEs with average onset timing with respect to the QRS complex of -31.7, +46, +365 and +536 ms. The late diastolic PE propagated apex to base in all participants at an average velocity of 3.4 m/s by the RMD. The RMD of the amyloidosis patient revealed significant changes in the appearance of PEs compared with normal participants. The late diastolic PE propagated at 5.3 m/s from apex to base. All four PEs lagged the average timing of normal participants.; Conclusion: The RMD method reliably reveals PEs as discrete events and successfully allows reproducible measurement of PE timing and the velocity of at least one PE. The RMD method is applicable to live, clinical high-speed studies and may offer a new approach to characterization of cardiac function.; (Copyright © 2023 World Federation for Ultrasound in Medicine & Biology. Published by Elsevier Inc. All rights reserved.) |
| Competing Interests: | Conflict of interest O.T.v.R. is the Chief Technology Officer of Volumetrics Medical Systems. The remaining authors declare no competing interests. |
| Contributed Indexing: | Keywords: Difference imaging; Echocardiography; High frame rate; Myocardial vibrations; Regional motion display |
| Entry Date(s): | Date Created: 20230329 Date Completed: 20230418 Latest Revision: 20230510 |
| Update Code: | 20260130 |
| DOI: | 10.1016/j.ultrasmedbio.2023.02.006 |
| PMID: | 36990961 |
| Database: | MEDLINE |
Journal Article