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Necrotizing Sweet Syndrome of the Hand and Forearm in the Immediate Postoperative Period: Case Report.

Title: Necrotizing Sweet Syndrome of the Hand and Forearm in the Immediate Postoperative Period: Case Report.
Authors: Hresko AM; Harvard Combined Orthopaedics Residency Program, Massachusetts General Hospital, Boston, USA.; Pickrell BB; Department of Orthopaedic Surgery, Beth Israel Deaconess Medical Center, Boston, MA, USA.; Harper CM; Department of Orthopaedic Surgery, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Source: Hand (New York, N.Y.) [Hand (N Y)] 2024 Oct; Vol. 19 (7), pp. NP1-NP7. Date of Electronic Publication: 2023 Nov 09.
Publication Type: Case Reports; Journal Article
Language: English
Journal Info: Publisher: SAGE Publications Country of Publication: United States NLM ID: 101264149 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1558-9455 (Electronic) Linking ISSN: 15589447 NLM ISO Abbreviation: Hand (N Y) Subsets: MEDLINE
Imprint Name(s): Publication: 2016- : Thousand Oaks, CA : SAGE Publications; Original Publication: New York, N.Y. : Springer, c2006-
MeSH Terms: Sweet Syndrome*/diagnosis ; Postoperative Complications*/diagnosis; Dupuytren Contracture/surgery ; Dupuytren Contracture/diagnosis ; Fasciotomy/methods ; Forearm/surgery ; Hand/surgery ; Humans ; Female ; Middle Aged ; Necrosis
Abstract: Necrotizing soft tissue infection (NSTI) is a feared and potentially morbid postoperative complication requiring prompt surgical intervention. Cutaneous conditions that mimic NSTI have been reported and rarely occur in the postoperative period. Sweet syndrome, also known as acute febrile neutrophilic dermatosis, is a dermatologic condition characterized by fever, neutrophil-predominant leukocytosis, and painful skin lesions. Necrotizing Sweet syndrome (NSS) is an aggressive variant that causes a clinical appearance of localized skin necrosis and histologic evidence of necrotic foci extending to the deep aspects of the soft tissues and involving fascia and/or skeletal muscle. Necrotizing Sweet syndrome can be easily mistaken for NSTI. Contrary to infection, Sweet syndrome and NSS are worsened by surgical intervention due to the phenomenon of pathergy and readily respond to corticosteroid treatment. We present the case of a 54-year-old woman who developed NSS following an uncomplicated fasciectomy for Dupuytren disease.
Competing Interests: Declaration of Conflicting InterestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
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Contributed Indexing: Keywords: diagnosis; infection; necrotizing Sweet syndrome; necrotizing soft tissue infection; postoperative complications; wound management
Entry Date(s): Date Created: 20231110 Date Completed: 20241015 Latest Revision: 20251002
Update Code: 20260130
PubMed Central ID: PMC11481154
DOI: 10.1177/15589447231207978
PMID: 37946497
Database: MEDLINE

Case Reports; Journal Article