Womandla Health: development and rationale of a behavioral intervention to support HIV treatment adherence among postpartum women in South Africa.
| Title: | Womandla Health: development and rationale of a behavioral intervention to support HIV treatment adherence among postpartum women in South Africa. |
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| Authors: | Pellowski JA; School of Public Health, Brown University, Providence, USA. Jennifer_pellowski@brown.edu.; School of Public Health, University of Cape Town, Cape Town, South Africa. Jennifer_pellowski@brown.edu.; Jensen D; School of Public Health, Brown University, Providence, USA.; Tsawe N; School of Public Health, University of Cape Town, Cape Town, South Africa.; Colvin C; School of Public Health, University of Cape Town, Cape Town, South Africa.; School of Medicine, University of Virginia, Charlottesville, USA.; Cu-Uvin S; The Warren Alpert Medical School of Brown University, Providence,, USA.; Operario D; Rollins School of Public Health, Emory University, Atlanta, Georgia.; Lurie M; School of Public Health, Brown University, Providence, USA.; School of Public Health, University of Cape Town, Cape Town, South Africa.; Harrison A; School of Public Health, Brown University, Providence, USA.; Myer L; School of Public Health, University of Cape Town, Cape Town, South Africa.; Knight L; School of Public Health, University of Cape Town, Cape Town, South Africa.; School of Public Health, University of the Western Cape, Cape Town, South Africa. |
| Source: | BMC women's health [BMC Womens Health] 2023 Dec 06; Vol. 23 (1), pp. 649. Date of Electronic Publication: 2023 Dec 06. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural |
| Language: | English |
| Journal Info: | Publisher: BioMed Central Country of Publication: England NLM ID: 101088690 Publication Model: Electronic Cited Medium: Internet ISSN: 1472-6874 (Electronic) Linking ISSN: 14726874 NLM ISO Abbreviation: BMC Womens Health Subsets: MEDLINE |
| Imprint Name(s): | Original Publication: [London] : BioMed Central, 2001- |
| MeSH Terms: | HIV Infections*/drug therapy ; HIV Infections*/psychology ; Pregnancy Complications, Infectious*/drug therapy ; Anti-HIV Agents*/therapeutic use; Medication Adherence/psychology ; Postpartum Period/psychology ; Anti-Retroviral Agents/therapeutic use ; Infectious Disease Transmission, Vertical/prevention & control ; Pregnancy ; Female ; Humans ; South Africa ; Treatment Adherence and Compliance |
| Abstract: | Background: While Option B + has made great strides in eliminating vertical transmission of HIV and improving access to lifelong antiretroviral therapy (ART) for women, the postpartum period remains a risk period for disengagement from HIV care and non-adherence.; Methods: Longitudinal qualitative data was collected from 30 women living with HIV in Cape Town, South Africa from pregnancy through 1 year postpartum to examine key barriers and facilitators to HIV treatment adherence across this transition. Participants were also asked about their preferences for behavioral intervention content, format, and scope. The intervention development process was guided by Fernandez et al.'s Intervention Mapping process and was informed by the qualitative data, the wider literature on ART adherence, and Transition Theory.; Results: The Womandla Health Intervention is a multicomponent intervention consisting of four individual sessions with a lay health worker and four peer group sessions, which span late pregnancy and early postpartum. These sessions are guided by Transition Theory and utilize motivational interviewing techniques to empower women to ascertain their own individual barriers to HIV care and identify solutions and strategies to overcome these barriers.; Conclusions: This intervention will be tested in a small scale RCT. If successful, findings will provide an innovative approach to HIV treatment by capitalizing on the transition into motherhood to bolster self-care behaviors, focusing on ART adherence and also women's overall postpartum health and psychosocial needs.; (© 2023. The Author(s).) |
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| Grant Information: | K01 MH112443 United States MH NIMH NIH HHS; R25 MH067127 United States MH NIMH NIH HHS; K01MH112443 United States MH NIMH NIH HHS |
| Contributed Indexing: | Keywords: Behavioral intervention; HIV; Postpartum; Pregnancy |
| Substance Nomenclature: | 0 (Anti-Retroviral Agents); 0 (Anti-HIV Agents) |
| Entry Date(s): | Date Created: 20231206 Date Completed: 20231211 Latest Revision: 20240726 |
| Update Code: | 20260130 |
| PubMed Central ID: | PMC10701937 |
| DOI: | 10.1186/s12905-023-02817-y |
| PMID: | 38057777 |
| Database: | MEDLINE |
Journal Article; Research Support, N.I.H., Extramural