Neutrophil: Lymphocyte and Platelet: Lymphocyte ratios measured before transplantation and their correlation with new-onset diabetes post-transplantation in renal transplant recipients.
| Title: | Neutrophil: Lymphocyte and Platelet: Lymphocyte ratios measured before transplantation and their correlation with new-onset diabetes post-transplantation in renal transplant recipients. |
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| Authors: | Dung NTT; Military Hospital 103, Ha Noi, Viet Nam; Vietnam Military Medical University, Ha Noi, Viet Nam.; Thuy PV; Kinh 7 Charity Clinic, Kien Giang, Viet Nam.; Tue NT; Military Hospital 103, Ha Noi, Viet Nam; Vietnam Military Medical University, Ha Noi, Viet Nam.; Kien TQ; Military Hospital 103, Ha Noi, Viet Nam; Vietnam Military Medical University, Ha Noi, Viet Nam.; Van Duc N; Military Hospital 103, Ha Noi, Viet Nam; Vietnam Military Medical University, Ha Noi, Viet Nam.; Van DT; Military Hospital 103, Ha Noi, Viet Nam; Vietnam Military Medical University, Ha Noi, Viet Nam.; Ha DM; Military Hospital 103, Ha Noi, Viet Nam; Vietnam Military Medical University, Ha Noi, Viet Nam.; Ha NTT; Military Hospital 103, Ha Noi, Viet Nam; Vietnam Military Medical University, Ha Noi, Viet Nam.; Nghia PB; Military Hospital 103, Ha Noi, Viet Nam; Vietnam Military Medical University, Ha Noi, Viet Nam.; Kien NT; Military Hospital 103, Ha Noi, Viet Nam; Vietnam Military Medical University, Ha Noi, Viet Nam.; Van Hinh T; Military Hospital 103, Ha Noi, Viet Nam; Vietnam Military Medical University, Ha Noi, Viet Nam.; Nui NM; Military Hospital 103, Ha Noi, Viet Nam; Vietnam Military Medical University, Ha Noi, Viet Nam.; Toan PQ; Military Hospital 103, Ha Noi, Viet Nam; Vietnam Military Medical University, Ha Noi, Viet Nam.; Loc ND; An Sinh Hospital, Ho Chi Minh, Viet Nam.; Ha DTV; Hanoi Medical University, Ha Noi, Viet Nam.; Tuyen DG; Hanoi Medical University, Ha Noi, Viet Nam.; Thang LV; Military Hospital 103, Ha Noi, Viet Nam; Vietnam Military Medical University, Ha Noi, Viet Nam. Electronic address: lethangviet@yahoo.co.uk. |
| Source: | Transplant immunology [Transpl Immunol] 2024 Feb; Vol. 82, pp. 101979. Date of Electronic Publication: 2024 Jan 04. |
| Publication Type: | Journal Article |
| Language: | English |
| Journal Info: | Publisher: Elsevier Country of Publication: Netherlands NLM ID: 9309923 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-5492 (Electronic) Linking ISSN: 09663274 NLM ISO Abbreviation: Transpl Immunol Subsets: MEDLINE |
| Imprint Name(s): | Publication: Amsterdam : Elsevier; Original Publication: Dunton Green, Sevenoaks, Kent, UK : Edward Arnold, c1993- |
| MeSH Terms: | Diabetes Mellitus*/diagnosis ; Diabetes Mellitus*/epidemiology ; Kidney Transplantation*; Adult ; Humans ; Neutrophils ; C-Reactive Protein ; Lymphocytes ; Kidney ; Retrospective Studies |
| Abstract: | Purpose: Our goal was to evaluate the neutrophil:lymphocyte (NLR) and platelet:lymphocyte (PLR) ratios measured before transplantation and their correlation with new-onset diabetes after transplantation (NODAT) in renal transplant recipients.; Patients and Methods: We conducted our study in 324 adult patients consecutively admitted to Military Hospital 103, Ha Noi, Viet Nam, who received kidney allografts from living donors. These patients were followed-up during the first 2 years post-transplantation for NODAT. We examined the association between NLR and PLR measured prior to transplantation in patients with NODAT: NLR and PLR were calculated based on the results of the complete blood count. The criteria for diagnosis of a fully symptomatic NODAT case were based on the guidelines established by the American Diabetes Association and included fasting venous blood glucose and glycosylated hemoglobin A1c (HbA1c) levels, with or without an oral glucose tolerance test.; Results: The overall rate of NODAT during the two years after kidney transplantation was 13.6%. We found mean values of age and body mass index (BMI), and median values of NLR, PLR, high sensitivity C-reactive protein (hs-CRP) levels, and the arteriosclerosis ratio in the NODAT group to be significantly higher than those of the non-NODAT group (all p |
| Competing Interests: | Declaration of competing interest The authors declare no conflict of interest, financial or otherwise. |
| Contributed Indexing: | Keywords: NLR; NODAT prediction; PLR; Renal transplant recipients |
| Substance Nomenclature: | 9007-41-4 (C-Reactive Protein) |
| Entry Date(s): | Date Created: 20240106 Date Completed: 20240129 Latest Revision: 20240306 |
| Update Code: | 20260130 |
| DOI: | 10.1016/j.trim.2023.101979 |
| PMID: | 38184212 |
| Database: | MEDLINE |
Journal Article