Ablation of persistent atrial fibrillation based on atrial electrogram duration map: methodology and clinical outcomes from the AEDUM pilot study.
| Title: | Ablation of persistent atrial fibrillation based on atrial electrogram duration map: methodology and clinical outcomes from the AEDUM pilot study. |
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| Authors: | Rossi P; Arrhythmology Unit, Ospedale Fatebenefratelli Isola Tiberina-Gemelli Isola, Via Ponte Quattro Capi, 39, 00186, Rome, Italy. rossi.ptr@gmail.com.; Cauti FM; Arrhythmology Unit, Ospedale Fatebenefratelli Isola Tiberina-Gemelli Isola, Via Ponte Quattro Capi, 39, 00186, Rome, Italy.; Polselli M; Arrhythmology Unit, Ospedale Fatebenefratelli Isola Tiberina-Gemelli Isola, Via Ponte Quattro Capi, 39, 00186, Rome, Italy.; Magnocavallo M; Arrhythmology Unit, Ospedale Fatebenefratelli Isola Tiberina-Gemelli Isola, Via Ponte Quattro Capi, 39, 00186, Rome, Italy.; Niscola M; Abbott Medical, Via Paracelso 20, 20864, Agrate Brianza, Italy.; Fanti V; Abbott Medical, Via Paracelso 20, 20864, Agrate Brianza, Italy.; Limite LR; Unité d'Arythmologie, Hôpital Privé Les Franciscaines, Nîmes, France.; Evangelista A; Arrhythmology Unit, Ospedale Fatebenefratelli Isola Tiberina-Gemelli Isola, Via Ponte Quattro Capi, 39, 00186, Rome, Italy.; Bellisario A; European Hospital, Via Portuense, 700, Rome, Italy.; De Paolis R; European Hospital, Via Portuense, 700, Rome, Italy.; Facchetti S; European Hospital, Via Portuense, 700, Rome, Italy.; Quaglione R; Department of Internal, Anesthesiology and Cardiovascular Sciences, Policlinico Umberto I, Sapienza University of Rome, 00185, Rome, Italy.; Piccirillo G; Department of Internal, Anesthesiology and Cardiovascular Sciences, Policlinico Umberto I, Sapienza University of Rome, 00185, Rome, Italy.; Bianchi S; Arrhythmology Unit, Ospedale Fatebenefratelli Isola Tiberina-Gemelli Isola, Via Ponte Quattro Capi, 39, 00186, Rome, Italy. |
| Source: | Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing [J Interv Card Electrophysiol] 2024 Sep; Vol. 67 (6), pp. 1365-1376. Date of Electronic Publication: 2024 Jan 11. |
| Publication Type: | Journal Article |
| Language: | English |
| Journal Info: | Publisher: Springer Country of Publication: Netherlands NLM ID: 9708966 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1572-8595 (Electronic) Linking ISSN: 1383875X NLM ISO Abbreviation: J Interv Card Electrophysiol Subsets: MEDLINE |
| Imprint Name(s): | Publication: Amsterdam : Springer; Original Publication: Norwell, MA : Kluwer Academic Publishers, c1997- |
| MeSH Terms: | Atrial Fibrillation*/surgery ; Atrial Fibrillation*/physiopathology ; Catheter Ablation*/methods; Body Surface Potential Mapping/methods ; Electrocardiography, Ambulatory/methods ; Humans ; Male ; Female ; Pilot Projects ; Middle Aged ; Treatment Outcome |
| Abstract: | Background: Catheter ablation of persistent atrial fibrillation (PsAF) represents a challenge for the electrophysiologist and there are still divergences regarding the best ablative approach to adopt. Create a new map of the duration of atrial bipolar electrograms (Atrial Electrogram DUration Map, AEDUM) to recognize a functional substrate during sinus rhythm and guide a patient-tailored ablative strategy for PsAF.; Methods: Forty PsAF subjects were assigned in a 1:1 ratio to either for PVI alone (Group B1) or PVI+AEDUM areas ablation (Group B2). A cohort of 15 patients without AF history undergoing left-sided accessory pathway ablation was used as a control group (Group A). In all patients, voltage and AEDUM maps were created during sinus rhythm. The minimum follow-up was 12 months, with rhythm monitoring via 48-h ECG Holter or by implantable cardiac device.; Results: Electrogram (EGM) duration was higher in Group B than in Group A (49±16.2ms vs 34.2±3.8ms; p-value |
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| Contributed Indexing: | Keywords: AEDUM; Atrial fibrillation; Catheter ablation; Persistent atrial fibrillation; Pulmonary vein isolation |
| Entry Date(s): | Date Created: 20240111 Date Completed: 20240906 Latest Revision: 20240910 |
| Update Code: | 20260130 |
| PubMed Central ID: | PMC11379763 |
| DOI: | 10.1007/s10840-023-01721-7 |
| PMID: | 38206451 |
| Database: | MEDLINE |
Journal Article