Post-Irradiation Breast Angiosarcoma: All the Possible Treatments and Electrochemotherapy. Case Report and Literature Review.
| Title: | Post-Irradiation Breast Angiosarcoma: All the Possible Treatments and Electrochemotherapy. Case Report and Literature Review. |
|---|---|
| Authors: | Parisi S; Department of Advanced Medical and Surgical Sciences, School of Medicine, University of Campania 'Luigi Vanvitelli', 80131 Naples, Italy.; Division of General, Oncological, Mini-Invasive and Obesity Surgery, University of Campania 'Luigi Vanvitelli', 80131 Naples, Italy.; Gambardella C; Department of Advanced Medical and Surgical Sciences, School of Medicine, University of Campania 'Luigi Vanvitelli', 80131 Naples, Italy.; Division of General, Oncological, Mini-Invasive and Obesity Surgery, University of Campania 'Luigi Vanvitelli', 80131 Naples, Italy.; Iovino F; Division of General, Oncological, Mini-Invasive and Obesity Surgery, University of Campania 'Luigi Vanvitelli', 80131 Naples, Italy.; Department of Translational Medical Sciences, Division of General Surgery, University of Campania 'Luigi Vanvitelli', 80131 Naples, Italy.; Ruggiero R; Department of Advanced Medical and Surgical Sciences, School of Medicine, University of Campania 'Luigi Vanvitelli', 80131 Naples, Italy.; Division of General, Oncological, Mini-Invasive and Obesity Surgery, University of Campania 'Luigi Vanvitelli', 80131 Naples, Italy.; Lucido FS; Department of Advanced Medical and Surgical Sciences, School of Medicine, University of Campania 'Luigi Vanvitelli', 80131 Naples, Italy.; Division of General, Oncological, Mini-Invasive and Obesity Surgery, University of Campania 'Luigi Vanvitelli', 80131 Naples, Italy.; Nesta G; Division of General, Oncological, Mini-Invasive and Obesity Surgery, University of Campania 'Luigi Vanvitelli', 80131 Naples, Italy.; Tolone S; Department of Advanced Medical and Surgical Sciences, School of Medicine, University of Campania 'Luigi Vanvitelli', 80131 Naples, Italy.; Division of General, Oncological, Mini-Invasive and Obesity Surgery, University of Campania 'Luigi Vanvitelli', 80131 Naples, Italy.; Brusciano L; Department of Advanced Medical and Surgical Sciences, School of Medicine, University of Campania 'Luigi Vanvitelli', 80131 Naples, Italy.; Division of General, Oncological, Mini-Invasive and Obesity Surgery, University of Campania 'Luigi Vanvitelli', 80131 Naples, Italy.; Fisone F; Division of General, Oncological, Mini-Invasive and Obesity Surgery, University of Campania 'Luigi Vanvitelli', 80131 Naples, Italy.; Mongardini FM; Division of General, Oncological, Mini-Invasive and Obesity Surgery, University of Campania 'Luigi Vanvitelli', 80131 Naples, Italy.; Cozzolino G; Division of General, Oncological, Mini-Invasive and Obesity Surgery, University of Campania 'Luigi Vanvitelli', 80131 Naples, Italy.; Della Corte CM; Medical Oncology, Department of Precision Medicine, University of Campania 'Luigi Vanvitelli', Via S. Pansini 5, 80131 Naples, Italy.; Napolitano S; Medical Oncology, Department of Precision Medicine, University of Campania 'Luigi Vanvitelli', Via S. Pansini 5, 80131 Naples, Italy.; Orditura M; Medical Oncology, Department of Precision Medicine, University of Campania 'Luigi Vanvitelli', Via S. Pansini 5, 80131 Naples, Italy.; Esposito R; Division of General, Oncological, Mini-Invasive and Obesity Surgery, University of Campania 'Luigi Vanvitelli', 80131 Naples, Italy.; Docimo L; Department of Advanced Medical and Surgical Sciences, School of Medicine, University of Campania 'Luigi Vanvitelli', 80131 Naples, Italy.; Division of General, Oncological, Mini-Invasive and Obesity Surgery, University of Campania 'Luigi Vanvitelli', 80131 Naples, Italy. |
| Source: | Journal of clinical medicine [J Clin Med] 2024 Jan 18; Vol. 13 (2). Date of Electronic Publication: 2024 Jan 18. |
| Publication Type: | Journal Article; Review |
| Language: | English |
| Journal Info: | Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 101606588 Publication Model: Electronic Cited Medium: Print ISSN: 2077-0383 (Print) Linking ISSN: 20770383 NLM ISO Abbreviation: J Clin Med Subsets: PubMed not MEDLINE |
| Imprint Name(s): | Original Publication: Basel, Switzerland : MDPI AG, [2012]- |
| Abstract: | Breast angiosarcoma is a rare malignancy, accounting for less than 1% of all soft tissue cancers. It comprises primitive and secondary subtypes, such as radiogenic breast angiosarcoma (RAS). Despite multimodal treatment, angiosarcomas represent an incurable disease for many patients and a significant cause of deterioration in their quality of life. Surgery is a cornerstone in management, but high recurrence rates are reported. Electrochemotherapy (ECT) is a practicable locoregional treatment for patients with advanced angiosarcoma as part of a multimodal therapeutic strategy. The palliative benefits of ECT include optimal patient compliance, good local hemostasis control, and positive local responses. Since only 22 cases are described in the literature, we reported a rare case of RAS treated with ECT after a multidisciplinary approach, including Next Generation Sequencing (NGS). A literature review on the feasibility of ECT in RAS management was also performed. |
| Competing Interests: | The authors have no conflicts of interest to declare. |
| References: | J Clin Med. 2023 Aug 02;12(15):. (PMID: 37568479); Acta Oncol. 2018 Jul;57(7):874-882. (PMID: 29577784); Bioelectricity. 2019 Dec 1;1(4):204-213. (PMID: 34471824); Curr Oncol. 2023 Nov 13;30(11):9895-9905. (PMID: 37999139); Int J Surg. 2019 Dec;72:196-197. (PMID: 31726109); Br J Dermatol. 2017 Aug;177(2):e27. (PMID: 28833026); Int J Surg. 2018 Apr;52:110-119. (PMID: 29474886); Int J Surg Case Rep. 2015;13:30-2. (PMID: 26092711); Breast Cancer Res Treat. 2015 May;151(1):131-40. (PMID: 25893585); Int J Surg. 2019 Dec;72:232-233. (PMID: 31759116); Eur J Cancer. 2016 Aug;63:41-52. (PMID: 27267144); J Surg Oncol. 2014 Mar;109(3):270-4. (PMID: 24165992); In Vivo. 2021 May-Jun;35(3):1669-1676. (PMID: 33910851); Front Oncol. 2022 Sep 30;12:986123. (PMID: 36249019); Oncology. 2015;89(4):205-14. (PMID: 26043723); Cancer. 1986 Jul 15;58(2):306-9. (PMID: 3719523); Dermatol Online J. 2012 Jun 15;18(6):14. (PMID: 22747938); Anticancer Res. 2001 Jul-Aug;21(4A):2483-8. (PMID: 11724311); Radiother Oncol. 2007 Dec;85(3):355-61. (PMID: 18023492); BMJ Case Rep. 2019 Jul 18;12(7):. (PMID: 31324666); Arch Pathol Lab Med. 2016 May;140(5):477-81. (PMID: 27128306); Radiol Oncol. 2020 Dec 29;55(1):77-81. (PMID: 33885245); Oncologist. 2018 Feb;23(2):234-242. (PMID: 28860410); J Surg Case Rep. 2022 May 18;2022(5):rjac199. (PMID: 35599994); Histopathology. 2006 Jan;48(1):106-14. (PMID: 16359542); Cancer Radiother. 2015 May;19(3):168-74. (PMID: 25863565); J Vasc Interv Radiol. 2016 Mar;27(3):444-6. (PMID: 26916941); Cancers (Basel). 2021 Sep 26;13(19):. (PMID: 34638300); Int J Surg. 2019 Dec;72:34-42. (PMID: 31618680); Anticancer Res. 2020 Nov;40(11):6485-6492. (PMID: 33109587); BMC Cancer. 2018 Apr 24;18(1):463. (PMID: 29690864); Ultrastruct Pathol. 2003 May-Jun;27(3):197-203. (PMID: 12775509); Case Rep Oncol Med. 2011;2011:517047. (PMID: 22611503); Eur J Cancer. 2014 Jul;50(10):1779-1788. (PMID: 24731859); Gland Surg. 2014 Feb;3(1):28-34. (PMID: 25083491); J Pathol. 2023 Aug;260(4):465-477. (PMID: 37350195); Int J Immunopathol Pharmacol. 2016 Sep;29(3):537-42. (PMID: 26872968); J Surg Oncol. 2016 Aug;114(2):246-53. (PMID: 27156580) |
| Contributed Indexing: | Keywords: breast angiosarcoma; electrochemotherapy; post-irradiation angiosarcoma |
| Entry Date(s): | Date Created: 20240123 Latest Revision: 20241023 |
| Update Code: | 20260130 |
| PubMed Central ID: | PMC10816174 |
| DOI: | 10.3390/jcm13020567 |
| PMID: | 38256700 |
| Database: | MEDLINE |
Journal Article; Review