Living well with chronic pain: a 12-month randomized controlled trial revealing impact from the digital pain self-management program EPIO.
| Title: | Living well with chronic pain: a 12-month randomized controlled trial revealing impact from the digital pain self-management program EPIO. |
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| Authors: | Solberg Nes L; Division of Medicine, Department of Digital Health Research, Oslo University Hospital, Oslo, Norway.; Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway.; Department of Psychiatry and Psychology, College of Medicine and Science, Mayo Clinic, Rochester, MN, USA.; Børøsund E; Division of Medicine, Department of Digital Health Research, Oslo University Hospital, Oslo, Norway.; Department of Nursing and Health Sciences, Faculty of Health and Social Sciences, University of South-Eastern Norway, Drammen, Norway.; Varsi C; Division of Medicine, Department of Digital Health Research, Oslo University Hospital, Oslo, Norway.; Faculty of Health and Social Sciences, University of South-Eastern Norway, Drammen, Norway.; Eide H; Division of Medicine, Department of Digital Health Research, Oslo University Hospital, Oslo, Norway.; Centre for Health and Technology, Faculty of Health and Social Sciences, University of South-Eastern Norway, Drammen, Norway.; Waxenberg LB; Department of Clinical & Health Psychology, College of Public Health and Health Professions, University of Florida, Gainesville, FL, USA.; Weiss KE; Department of Psychiatry and Psychology, College of Medicine and Science, Mayo Clinic, Rochester, MN, USA.; Morrison EJ; Department of Psychiatry and Psychology, College of Medicine and Science, Mayo Clinic, Rochester, MN, USA.; Støle HS; Division of Medicine, Department of Digital Health Research, Oslo University Hospital, Oslo, Norway.; Department of Child Health and Development, Norwegian Institute of Public Health, Oslo, Norway.; Kristjansdottir ÓB; Division of Medicine, Department of Digital Health Research, Oslo University Hospital, Oslo, Norway.; Norwegian National Advisory Unit on Learning and Mastery in Health, Oslo University Hospital, Oslo, Norway.; Mental Health Team West, Primary Care of the Capital Area, Reykjavik, Iceland.; Bostrøm K; Division of Medicine, Department of Digital Health Research, Oslo University Hospital, Oslo, Norway.; Strand EB; Division of Medicine, Department of Digital Health Research, Oslo University Hospital, Oslo, Norway.; Institute of Health, Faculty of Health Science, VID-Scientific University, Oslo, Norway.; Hagen MCS; Faculty of Health Sciences, Oslo Metropolitan University, Oslo, Norway.; Stubhaug A; Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway.; Department of Pain Management and Research, Oslo University Hospital, Oslo, Norway.; Regional Advisory Unit on Pain, Oslo University Hospital, Oslo, Norway.; Schreurs KMG; Department of Psychology, Health, and Technology, University of Twente, Enschede, Netherlands. |
| Source: | Pain reports [Pain Rep] 2024 Jul 02; Vol. 9 (4), pp. e1174. Date of Electronic Publication: 2024 Jul 02 (Print Publication: 2024). |
| Publication Type: | Journal Article |
| Language: | English |
| Journal Info: | Publisher: Wolters Kluwer Country of Publication: United States NLM ID: 101683899 Publication Model: eCollection Cited Medium: Internet ISSN: 2471-2531 (Electronic) Linking ISSN: 24712531 NLM ISO Abbreviation: Pain Rep Subsets: PubMed not MEDLINE |
| Imprint Name(s): | Original Publication: Baltimore, MD : Wolters Kluwer, [2016]- |
| Abstract: | Introduction: Chronic pain affects a wide range of physical and psychological aspects of life for those impacted. Psychosocial treatment approaches may be of support, but outreach is still limited.; Objectives: To evaluate the efficacy of EPIO, an evidence-informed, user-centered digital self-management intervention for people with chronic pain, in a 12-month randomized controlled trial.; Methods: People living with chronic pain (N = 266) were randomized to the EPIO intervention (n = 132) or a usual-care control group (n = 134). The intervention was delivered in a simple blended care model, and outcome measures collected at baseline, 6 months, and 12 months. Generalized linear models for repeated measures were fitted to compare groups over time.; Results: Participants were primarily female (81%), median age 49 years (range 22-78), with heterogeneous pain conditions, and had lived with pain >5 years (77.6%). A mixed linear model with all timepoints included revealed no statistically significant group differences for the primary outcome of pain interference. Significant psychological benefits in favor of the intervention group were however detected for depression (P = 0.022), self-regulatory fatigue (P = 0.024), vitality (P = 0.016), and mental health (P = 0.047). Baseline to 12-month changes showed additional favorable effects for anxiety (between-group mean differences [MDs] = 0.79, P = 0.047), depression (MD = 1.08, P = 0.004), self-regulatory fatigue (MD = 2.42, P = 0.021), pain catastrophizing (MD = 2.62, P = 0.009), and health-related quality of life.; Conclusions: The EPIO program aims to improve outreach of evidence-based pain self-management interventions. Findings demonstrate how using EPIO can lead to sustainable psychological change, enhancing mental health and health-related quality of life for people suffering from pain, providing a chance to live well with the pain.; (Copyright © 2024 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of The International Association for the Study of Pain.) |
| Competing Interests: | L.S.N. is an unpaid board member of the company dHealth AS, aiming to market the EPIO program for commercialization, but has no financial interest in the company. The remaining authors have no conflicts of interest to declare. This study was funded by the Norwegian Research Council (Grant #256574, Principal Investigator L.Solberg Nes). Data sets from this study are, due to the nature of patient sensitive information, not available for public sharing through public archives or repositories. Deidentified data from this study will however be made available in accordance with institutional standards through contacting the corresponding author. Trial Registration: ClinicalTrials.gov NCT03705104.Sponsorships or competing interests that may be relevant to content are disclosed at the end of this article. |
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| Contributed Indexing: | Keywords: Acceptance and commitment therapy; Anxiety; Chronic pain; Cognitive behavioral therapy; Depression; Digital pain self-management; Pain interference; Psychosocial self-management; Self-regulatory fatigue; eHealth |
| Entry Date(s): | Date Created: 20240704 Latest Revision: 20240705 |
| Update Code: | 20260130 |
| PubMed Central ID: | PMC11221858 |
| DOI: | 10.1097/PR9.0000000000001174 |
| PMID: | 38962688 |
| Database: | MEDLINE |
Journal Article