Exercise training for patients with heart failure and preserved ejection fraction. A narrative review.
| Title: | Exercise training for patients with heart failure and preserved ejection fraction. A narrative review. |
|---|---|
| Authors: | Caminiti G; Department of Human Science and Promotion of Quality of Life, San Raffaele Open University, Rome; Cardiology Rehabilitation Unit, IRCCS San Raffaele, Rome.; Volterrani M; Department of Human Science and Promotion of Quality of Life, San Raffaele Open University, Rome; Cardiology Rehabilitation Unit, IRCCS San Raffaele, Rome.; Iellamo F; Division of Cardiology and Sports Medicine, Department of Clinical Sciences and Translational Medicine, Tor Vergata University, Rome.; Marazzi G; Cardiology Rehabilitation Unit, IRCCS San Raffaele, Rome.; Silvestrini M; Division of Cardiology and Sports Medicine, Department of Clinical Sciences and Translational Medicine, Tor Vergata University, Rome.; Giamundo DM; Department of Systems Medicine, Tor Vergata University, Rome.; Morsella V; Cardiology Rehabilitation Unit, IRCCS San Raffaele, Rome.; Di Biasio D; Cardiology Rehabilitation Unit, IRCCS San Raffaele, Rome.; Franchini A; Cardiology Rehabilitation Unit, IRCCS San Raffaele, Rome.; Perrone MA; Division of Cardiology and Sports Medicine, Department of Clinical Sciences and Translational Medicine, Tor Vergata University, Rome. |
| Source: | Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace [Monaldi Arch Chest Dis] 2025 Oct 14; Vol. 95 (3). Date of Electronic Publication: 2024 Jul 23. |
| Publication Type: | Journal Article; Review |
| Language: | English |
| Journal Info: | Publisher: PAGEPress Country of Publication: Italy NLM ID: 9307314 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2532-5264 (Electronic) Linking ISSN: 11220643 NLM ISO Abbreviation: Monaldi Arch Chest Dis Subsets: MEDLINE |
| Imprint Name(s): | Publication: Pavia, Italy : PAGEPress; Original Publication: Pavia : Fondazione clinica del lavoro edizioni : Distributed by PI-ME tipographia, c1993- |
| MeSH Terms: | Heart Failure*/physiopathology ; Heart Failure*/rehabilitation ; Heart Failure*/therapy ; Stroke Volume*/physiology ; Exercise Therapy*/methods; Exercise Tolerance/physiology ; Humans ; Quality of Life ; Female ; Comorbidity |
| Abstract: | Heart failure with preserved ejection fraction (HFpEF) remains a significant global health challenge, accounting for up to 50% of all heart failure cases and predominantly affecting the elderly and women. Despite advancements in therapeutic strategies, HFpEF's complexity poses substantial challenges in management, particularly due to its high comorbidity burden, including renal failure, atrial fibrillation, and obesity, among others. These comorbidities not only complicate the pathophysiology of HFpEF but also exacerbate its symptoms, necessitating a personalized approach to treatment focused on comorbidity management and symptom alleviation. In heart failure with reduced ejection fraction, exercise training (ET) was effective in improving exercise tolerance, quality of life, and reducing hospitalizations. However, the efficacy of ET in HFpEF patients remains less understood, with limited studies showing mixed results. Exercise intolerance is a key symptom in HFpEF patients, and it has a multifactorial origin since both central and peripheral oxygen mechanisms of transport and utilization are often compromised. Recent evidence underscores the potential of supervised ET in enhancing exercise tolerance and quality of life among HFpEF patients; however, the literature remains sparse and predominantly consists of small-scale studies. This review highlights the critical role of exercise intolerance in HFpEF and synthesizes current knowledge on the benefits of ET. It also calls for a deeper understanding and further research into exercise-based interventions and their underlying mechanisms, emphasizing the need for larger, well-designed studies to evaluate the effectiveness of ET in improving outcomes for HFpEF patients. |
| Entry Date(s): | Date Created: 20240726 Date Completed: 20251021 Latest Revision: 20251021 |
| Update Code: | 20260130 |
| DOI: | 10.4081/monaldi.2024.3030 |
| PMID: | 39058025 |
| Database: | MEDLINE |
Journal Article; Review