Gender Differences in Survival after Coronary Artery Bypass Grafting-13-Year Results from KROK Registry.
| Title: | Gender Differences in Survival after Coronary Artery Bypass Grafting-13-Year Results from KROK Registry. |
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| Authors: | Hirnle G; Department of Cardiac Surgery, Medical University of Bialystok, 15-276 Bialystok, Poland.; Stankiewicz A; Department of Cardiac Surgery, Medical University of Bialystok, 15-276 Bialystok, Poland.; Mitrosz M; Department of Cardiac Surgery, Medical University of Bialystok, 15-276 Bialystok, Poland.; Aboul-Hassan SS; Department of Cardiac Surgery and Interventional Cardiology, Faculty of Medicine and Medical Sciences, University of Zielona Gora, 65-417 Zielona Gora, Poland.; Deja M; Department of Cardiac Surgery, Upper-Silesian Medical Centre, Medical University of Silesia, 40-055 Katowice, Poland.; Rogowski J; Department of Cardiac and Vascular Surgery, Medical University of Gdansk, 80-211 Gdansk, Poland.; Cichoń R; Lower Silesian Center for Heart Diseases 'Medinet', Faculty of Medicine and Medical Sciences, University of Zielona Gora, 65-417 Zielona Gora, Poland.; Anisimowicz L; Department of Cardiac Surgery, Dr Antoni Jurasz Memorial University Hospital, 85-094 Bydgoszcz, Poland.; Bugajski P; Department of Cardiac Surgery, J. Struś Hospital, 61-285 Poznan, Poland.; Tobota Z; Department of Paediatric Cardiothoracic Surgery, Children's Memorial Health Institute, 01-210 Warszawa, Poland.; Maruszewski B; Department of Paediatric Cardiothoracic Surgery, Children's Memorial Health Institute, 01-210 Warszawa, Poland.; Hrapkowicz T; Department of Cardiac Surgery, Vascular Surgery and Transplantology, Silesian Centre for Heart Diseases, Medical University of Silesia, 41-800 Zabrze, Poland. |
| Corporate Authors: | KROK Investigators |
| Source: | Journal of clinical medicine [J Clin Med] 2024 Jul 12; Vol. 13 (14). Date of Electronic Publication: 2024 Jul 12. |
| Publication Type: | Journal Article |
| Language: | English |
| Journal Info: | Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 101606588 Publication Model: Electronic Cited Medium: Print ISSN: 2077-0383 (Print) Linking ISSN: 20770383 NLM ISO Abbreviation: J Clin Med Subsets: PubMed not MEDLINE |
| Imprint Name(s): | Original Publication: Basel, Switzerland : MDPI AG, [2012]- |
| Abstract: | The influence of gender on both early and long-term outcomes of coronary artery bypass grafting (CABG) is not clearly defined. Objectives: This study aimed to assess the impact of gender on early and long-term mortality after CABG using data from the KROK Registry. Methods: All 133,973 adult patients who underwent CABG in Poland between 1 January 2009 and 31 December 2019 were included in the Polish National Registry of Cardiac Surgical Procedures (KROK Registry). The study enrolled 90,541 patients: 68,401 men (75.55%) and 22,140 women (24.45%) who met the inclusion criteria. Then, 30-day mortality, 1-year mortality, and long-term mortality rates were compared. Results: Advanced age, higher Canadian Cardiovascular Society (CCS) and New York Heart Association (NYHA) grade, diabetes, hypercholesterolemia, arterial hypertension, body mass index BMI > 35 kg/m2, and renal failure, before the propensity matching, were more frequently observed in women. Women more frequently underwent urgent surgery, including single and double graft surgery, and off-pump CABG (OPCAB) (p < 0.001). In propensity-matched groups, early mortality (30 days) was significantly higher in women (3.4% versus 2.8%, p < 0.001). The annual mortality remained higher in this group (6.6% versus 6.0%, p = 0.025). However, long-term mortality differed significantly between the groups and was higher in the male group (33.0% men versus 28.8% women, p < 0.001). Conclusions: There are no apparent differences in long-term mortality between the two sexes in the entire population. In propensity-matched patients, early mortality was lower for men, but the long-term survival was found to be better in women. |
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| Contributed Indexing: | Keywords: coronary artery bypass grafting; gender differences; long-term survival |
| Entry Date(s): | Date Created: 20240727 Latest Revision: 20240729 |
| Update Code: | 20260130 |
| PubMed Central ID: | PMC11277894 |
| DOI: | 10.3390/jcm13144080 |
| PMID: | 39064120 |
| Database: | MEDLINE |
Journal Article