Campylobacteriosis Outbreak Linked to Municipal Water, Nebraska, USA, 20211.
| Title: | Campylobacteriosis Outbreak Linked to Municipal Water, Nebraska, USA, 20211. |
|---|---|
| Authors: | Jansen L; Birn R; Koirala S; Oppegard S; Loeck B; Hamik J; Wyckoff E; Spindola D; Dempsey S; Bartling A; Roundtree A; Kahler A; Lane C; Hogan N; Strockbine N; McKeel H; Yoder J; Mattioli M; Donahue M; Buss B |
| Source: | Emerging infectious diseases [Emerg Infect Dis] 2024 Oct; Vol. 30 (10), pp. 1998-2005. |
| Publication Type: | Journal Article; Review |
| Language: | English |
| Journal Info: | Publisher: National Center for Infectious Diseases, Centers for Disease Control and Prevention (CDC) Country of Publication: United States NLM ID: 9508155 Publication Model: Print Cited Medium: Internet ISSN: 1080-6059 (Electronic) Linking ISSN: 10806040 NLM ISO Abbreviation: Emerg Infect Dis Subsets: MEDLINE |
| Imprint Name(s): | Original Publication: Atlanta, GA : National Center for Infectious Diseases, Centers for Disease Control and Prevention (CDC), [1995- |
| MeSH Terms: | Campylobacter Infections*/epidemiology ; Campylobacter Infections*/microbiology ; Disease Outbreaks* ; Water Microbiology*; Nebraska/epidemiology ; Campylobacter jejuni/isolation & purification ; Campylobacter jejuni/genetics ; Drinking Water/microbiology ; Feces/microbiology ; Humans ; Middle Aged ; Male ; Adult ; Female ; Aged ; Child ; Adolescent ; Young Adult ; Child, Preschool ; Whole Genome Sequencing ; Case-Control Studies |
| Abstract: | In September 2021, eight campylobacteriosis cases were identified in a town in Nebraska, USA. We assessed potential exposures for a case-control analysis. We conducted whole-genome sequencing on Campylobacter isolates from patients' stool specimens. We collected large-volume dead-end ultrafiltration water samples for Campylobacter and microbial source tracking testing at the Centers for Disease Control and Prevention. We identified 64 cases in 2 waves of illnesses. Untreated municipal tap water consumption was strongly associated with illness (wave 1 odds ratio 15.36; wave 2 odds ratio 16.11). Whole-genome sequencing of 12 isolates identified 2 distinct Campylobacter jejuni subtypes (1 subtype/wave). The town began water chlorination, after which water testing detected coliforms. One dead-end ultrafiltration sample yielded nonculturable Campylobacter and avian-specific fecal rRNA genomic material. Our investigation implicated contaminated, untreated, municipal water as the source. Results of microbial source tracking supported mitigation with continued water chlorination. No further campylobacteriosis cases attributable to water were reported. |
| References: | J Microbiol Methods. 2021 Jan;180:106091. (PMID: 33137355); Int J Epidemiol. 2007 Aug;36(4):873-80. (PMID: 17389718); MMWR Morb Mortal Wkly Rep. 2017 Aug 11;64(53):1-143. (PMID: 28796757); Clin Infect Dis. 2007 Feb 15;44(4):506-12. (PMID: 17243052); Epidemiol Infect. 2017 Mar;145(4):701-709. (PMID: 27903324); J Water Health. 2017 Feb;15(1):83-96. (PMID: 28151442); Front Sustain Food Syst. 2020 Feb;3:. (PMID: 32440656); Water Res. 2013 Nov 15;47(18):6812-28. (PMID: 23880218); Water Res. 2022 Oct 15;225:119162. (PMID: 36191524); Appl Environ Microbiol. 2009 Aug;75(16):5284-9. (PMID: 19561183); MMWR Morb Mortal Wkly Rep. 2019 Feb 22;68(7):169-173. (PMID: 30789878); Appl Environ Microbiol. 2014 May;80(10):3086-94. (PMID: 24610857); Am J Public Health. 1997 Apr;87(4):580-4. (PMID: 9146435); J Appl Microbiol. 2010 Mar;108(3):974-984. (PMID: 19735325) |
| Contributed Indexing: | Keywords: Campylobacter infections; Campylobacteriosis; Nebraska; United States; bacteria; outbreaks; water |
| Substance Nomenclature: | 0 (Drinking Water) |
| Entry Date(s): | Date Created: 20240925 Date Completed: 20240925 Latest Revision: 20241003 |
| Update Code: | 20260130 |
| PubMed Central ID: | PMC11431921 |
| DOI: | 10.3201/eid3010.231509 |
| PMID: | 39320141 |
| Database: | MEDLINE |
Journal Article; Review