Validation and correlation of high-sensitive troponin I and troponin T in the emergency department.
| Title: | Validation and correlation of high-sensitive troponin I and troponin T in the emergency department. |
|---|---|
| Authors: | Nseir M; Department of Internal and Emergency Medicine, Trelleborg Hospital, Trelleborg, Sweden.; Mokhtari A; Department of Cardiology, Lund University, Skåne University Hospital, Entrégatan 7, Lund, 221 85, Sweden.; Lund University, Department of Clinical Sciences, Lund, Sweden.; Stanisic M; Department of Internal and Emergency Medicine, Trelleborg Hospital, Trelleborg, Sweden.; Ekström U; Department of Clinical Chemistry, Lund University, Skåne University Hospital, Lund, Sweden.; Labaf A; Department of Cardiology, Lund University, Skåne University Hospital, Entrégatan 7, Lund, 221 85, Sweden. ashkan.labaf@med.lu.se.; Lund University, Department of Clinical Sciences, Lund, Sweden. ashkan.labaf@med.lu.se. |
| Source: | BMC cardiovascular disorders [BMC Cardiovasc Disord] 2024 Oct 12; Vol. 24 (1), pp. 551. Date of Electronic Publication: 2024 Oct 12. |
| Publication Type: | Journal Article; Validation Study |
| Language: | English |
| Journal Info: | Publisher: BioMed Central Country of Publication: England NLM ID: 100968539 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2261 (Electronic) Linking ISSN: 14712261 NLM ISO Abbreviation: BMC Cardiovasc Disord Subsets: MEDLINE |
| Imprint Name(s): | Original Publication: London : BioMed Central, [2001- |
| MeSH Terms: | Troponin T*/blood ; Troponin I*/blood ; Biomarkers*/blood ; Myocardial Infarction*/blood ; Myocardial Infarction*/diagnosis ; Myocardial Infarction*/mortality ; Emergency Service, Hospital* ; Predictive Value of Tests*; Humans ; Male ; Female ; Middle Aged ; Aged ; Reproducibility of Results ; Up-Regulation ; Adult ; Retrospective Studies ; Prognosis ; Aged, 80 and over |
| Abstract: | Background: Troponin elevation is frequently observed in various scenarios in the Emergency Department (ED), yet there is a paucity of studies investigating simultaneously measured high-sensitivity cardiac troponin T (hs-cTnT) and troponin I (hs-cTnI) within a diverse cohort in a clinical setting.; Methods: All patients who underwent troponin testing at a single center were eligible for this study. Only patients with simultaneous samples with hs-cTnI (Siemens) and hs-cTnT (Roche) were included, regardless of chief complaint.; Results: Analysis of 1987 samples from 1134 patients showed a significant correlation between hs-cTnT and hs-cTnI (r = 0.86, p |
| References: | J Am Coll Cardiol. 2015 Apr 28;65(16):1655-1664. (PMID: 25908071); Cardiovasc Res. 2017 Dec 1;113(14):1708-1718. (PMID: 29016754); Circulation. 2018 Sep 4;138(10):989-999. (PMID: 29691270); Eur Heart J Acute Cardiovasc Care. 2023 Jun 2;12(6):355-363. (PMID: 36848390); Circulation. 2015 Jun 9;131(23):2032-40. (PMID: 25948541); Clin Chem. 2010 Feb;56(2):254-61. (PMID: 19959623); Eur Heart J. 2012 Sep;33(18):2265-71. (PMID: 22745356); Clin Chim Acta. 2011 Apr 11;412(9-10):748-54. (PMID: 21219893); Clin Chem. 2015 Feb;61(2):368-78. (PMID: 25451868); Eur Heart J. 1998 Nov;19 Suppl N:N25-9. (PMID: 9857935); Heart. 2019 Apr;105(8):616-622. (PMID: 30442743); J Am Coll Cardiol. 2012 Dec 11;60(23):2427-63. (PMID: 23154053); Clin Biochem. 2020 Apr;78:10-17. (PMID: 31899280); Clin Chem. 2018 Mar;64(3):515-525. (PMID: 29343534); Circulation. 2019 Jun 11;139(24):2754-2764. (PMID: 31014085); Eur J Epidemiol. 2017 Sep;32(9):765-773. (PMID: 28983736); J Am Med Dir Assoc. 2015 Oct 1;16(10):884-91. (PMID: 26255708); Biochem Med (Zagreb). 2022 Jun 15;32(2):020709. (PMID: 35799986); Clin Chem. 2019 Jul;65(7):893-904. (PMID: 30988172); Int J Cardiol. 2016 Nov 1;222:819-825. (PMID: 27522381); Diagnostics (Basel). 2022 Jan 21;12(2):. (PMID: 35204367); Am J Emerg Med. 2015 Sep;33(9):1258-60. (PMID: 26119904); Am J Med. 2017 Oct;130(10):1205-1210. (PMID: 28396229); Eur Heart J. 2014 Feb;35(6):365-75. (PMID: 23821402); Clin Chem Lab Med. 2022 Nov 28;61(3):380-387. (PMID: 36424851); Int J Cardiol. 2018 May 15;259:186-191. (PMID: 29477263); Open Heart. 2018 Oct 15;5(2):e000859. (PMID: 30364505) |
| Contributed Indexing: | Keywords: Correlation; Myocardial infarction; Prognosis; Sensitivity; Specificity; Troponin I; Troponin T |
| Substance Nomenclature: | 0 (Troponin T); 0 (Troponin I); 0 (Biomarkers) |
| Entry Date(s): | Date Created: 20241012 Date Completed: 20241012 Latest Revision: 20260428 |
| Update Code: | 20260429 |
| PubMed Central ID: | PMC11470706 |
| DOI: | 10.1186/s12872-024-04230-1 |
| PMID: | 39395935 |
| Database: | MEDLINE |
Journal Article; Validation Study