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Sex Differences in Subclinical Psychotic Experiences: The Role of Daily-Life Social Interactions.

Title: Sex Differences in Subclinical Psychotic Experiences: The Role of Daily-Life Social Interactions.
Authors: Akcaoglu Z; Department of Neurosciences, Center for Contextual Psychiatry, Research Group Psychiatry, KU Leuven, 3000 Leuven, Belgium.; Myin-Germeys I; Department of Neurosciences, Center for Contextual Psychiatry, Research Group Psychiatry, KU Leuven, 3000 Leuven, Belgium.; Vaessen T; Department of Neurosciences, Center for Contextual Psychiatry, Research Group Psychiatry, KU Leuven, 3000 Leuven, Belgium.; Department of Psychology, Health & Technology, Faculty of Behavioral, Management, and Social Sciences (BMS), University of Twente, 7522 NB Enschede, The Netherlands.; Janssens JJ; Department of Neurosciences, Center for Contextual Psychiatry, Research Group Psychiatry, KU Leuven, 3000 Leuven, Belgium.; Wampers M; Department of Neurosciences, Center for Contextual Psychiatry, Research Group Psychiatry, KU Leuven, 3000 Leuven, Belgium.; Department of Neurosciences, UPC KU Leuven, Campus Kortenberg, 3070 Kortenberg, Belgium.; Bamps E; Department of Neurosciences, Center for Contextual Psychiatry, Research Group Psychiatry, KU Leuven, 3000 Leuven, Belgium.; Lafit G; Department of Neurosciences, Center for Contextual Psychiatry, Research Group Psychiatry, KU Leuven, 3000 Leuven, Belgium.; Methodology of Educational Sciences, Faculty of Psychology, KU Leuven, 3000 Leuven, Belgium.; Kirtley OJ; Department of Neurosciences, Center for Contextual Psychiatry, Research Group Psychiatry, KU Leuven, 3000 Leuven, Belgium.; Achterhof R; Department of Neurosciences, Center for Contextual Psychiatry, Research Group Psychiatry, KU Leuven, 3000 Leuven, Belgium.; Department of Psychology, Education and Child Studies, Erasmus University Rotterdam, 3062 PA Rotterdam, The Netherlands.
Source: Schizophrenia bulletin [Schizophr Bull] 2026 Mar 07; Vol. 52 (2).
Publication Type: Journal Article
Language: English
Journal Info: Publisher: Oxford University Press Country of Publication: United States NLM ID: 0236760 Publication Model: Print Cited Medium: Internet ISSN: 1745-1701 (Electronic) Linking ISSN: 05867614 NLM ISO Abbreviation: Schizophr Bull Subsets: MEDLINE
Imprint Name(s): Publication: 2005- : Cary, NC : Oxford University Press; Original Publication: [Chevy Chase, Md., For sale by the Supt. of Docs., U. S. Govt. Print. Off. Washington]
MeSH Terms: Psychotic Disorders*/epidemiology ; Psychotic Disorders*/physiopathology ; Social Interaction* ; Psychological Distress*; Belgium/epidemiology ; Humans ; Female ; Male ; Adolescent ; Young Adult ; Sex Factors ; Adult
Abstract: Background and Hypothesis: Sex differences in psychosis are reported across the psychosis spectrum, including in subclinical stages. An important factor in understanding these variations is the subjective experience of everyday social interactions (SI). We investigated whether the presence of psychotic experiences (PEs), as well as associated distress, differs between men and women. We focused on the role of daily-life SI quality and whether its association with PEs varies by sex.; Study Design: We included adolescents from SIGMA, a general youth population study in Flanders, Belgium (n = 344; mean age = 18.7; 63.4% female). Psychotic experiences were measured using the PQ-16. We used Experience Sampling Methodology to assess daily-life SI. A multilevel model and multiple linear regressions were used to assess, respectively, the relationship between sex and SI quality and whether PEs and their association with SI quality differ between young men and women.; Study Results: The results of the multilevel linear regression model indicate that the prevalence of and distress associated with PEs were higher in women. No significant difference was observed in the subjective quality of daily SI. Social interaction quality was strongly related to PEs. This association did not seem to vary for the prevalence of PEs, though women's distress about PEs appeared to be more affected by SI quality.; Conclusions: Present findings highlight the role of the subjective quality of SI in subclinical psychosis. More research is needed to investigate the mechanisms through which SI quality relates to PEs, and whether these differ between young men and women.; (© The Author(s) 2024. Published by Oxford University Press on behalf of the Maryland Psychiatric Research Center. All rights reserved. For commercial re-use, please contact reprints@oup.com for reprints and translation rights for reprints. All other permissions can be obtained through our RightsLink service via the Permissions link on the article page on our site—for further information please contact journals.permissions@oup.com.)
Grant Information: FWO GOF8416N Research Foundation Flanders; 2020-J5200810-E0XX King Baudouin Foundation United States
Contributed Indexing: Keywords: experience sampling methodology; gender; general population; psychosis; social company; youth mental health
Entry Date(s): Date Created: 20241020 Date Completed: 20260318 Latest Revision: 20260320
Update Code: 20260320
PubMed Central ID: PMC12996914
DOI: 10.1093/schbul/sbae177
PMID: 39428114
Database: MEDLINE

Journal Article