Anticoagulation in the context of post-intracerebral haemorrhage: A narrative review.
| Title: | Anticoagulation in the context of post-intracerebral haemorrhage: A narrative review. |
|---|---|
| Authors: | Tran T; MBBS, FRACP (General acute care medicine), Aged Care Advanced Trainee, Bankstown Lidcombe Hospital, Sydney, NSW; UNSW Conjoint Associate Lecturer, Faculty of Medicine, UNSW, Sydney, NSW.; Tsolakis J; BSc (Adv), MD, Basic Physician Trainee, Royal Prince Alfred Hospital, Sydney, NSW; Conjoint Associate Lecturer, School of Medicine and Public Health, University of Newcastle, NSW.; O'Rourke F; MBBS, FRACP, Aged Care Senior Staff Specialist, Bankstown Lidcombe Hospital, Sydney, NSW; Conjoint Senior Lecturer, Faculty of Medicine, UNSW, Sydney, NSW. |
| Source: | Australian journal of general practice [Aust J Gen Pract] 2024 Nov Supplement; Vol. 53 (11 Suppl), pp. S19-S22. |
| Publication Type: | Journal Article; Review |
| Language: | English |
| Journal Info: | Publisher: Royal Australian College of General Practitioners Country of Publication: Australia NLM ID: 101718099 Publication Model: Print Cited Medium: Internet ISSN: 2208-7958 (Electronic) NLM ISO Abbreviation: Aust J Gen Pract Subsets: MEDLINE |
| Imprint Name(s): | Original Publication: East Melbourne, Victoria : Royal Australian College of General Practitioners, [2018]- |
| MeSH Terms: | Anticoagulants*/therapeutic use ; Anticoagulants*/adverse effects ; Cerebral Hemorrhage*/complications; Thromboembolism/prevention & control ; Thromboembolism/etiology ; Humans ; Risk Factors ; Administration, Oral |
| Abstract: | Background: Recommencement of oral anticoagulation (OAC) for patients post-intracerebral haemorrhage (ICH) remains a challenging decision for clinicians. High-quality evidence to assist with this decision is lacking and current guidelines primarily focus on balancing thromboembolic and bleeding risk.; Objective: This study evaluated the literature and current guidelines for recommencement of OAC in patients who have experienced an incident ICH.; Discussion: Patients with recurrent ICH while on anticoagulation therapy have associated poor outcomes. However, predicting which patients will experience recurrent ICH with OAC resumption remains challenging, and failure to resume OAC carries risks of thromboembolic events. Current data suggest that it is reasonable to resume OAC in many patients post-ICH, depending on careful consideration of individual risk factors for haemorrhagic and thromboembolic events. The application of existing risk stratification tools for thromboembolism and haemorrhage, and radiological biomarkers such as cerebral microbleeds, might also assist in decision making. |
| Substance Nomenclature: | 0 (Anticoagulants) |
| Entry Date(s): | Date Created: 20241114 Date Completed: 20241115 Latest Revision: 20260503 |
| Update Code: | 20260503 |
| DOI: | 10.31128/AJGP-09-23-6970 |
| PMID: | 39542669 |
| Database: | MEDLINE |
Journal Article; Review