[Efficacy and safety of osteoporosis treatment in older adults. Approach for the secondary prevention of fractures in older populations. A proposal by SEFRAOS].
| Title: | [Efficacy and safety of osteoporosis treatment in older adults. Approach for the secondary prevention of fractures in older populations. A proposal by SEFRAOS]. |
|---|---|
| Transliterated Title: | Eficacia y seguridad del tratamiento de la osteoporosis en el anciano. Propuesta de SEFRAOS para abordaje de la prevención secundaria de fracturas en el adulto mayor. |
| Authors: | Cuadra-Llopart L; Department of Geriatric Medicine, Orthogeriatric Unit, Hospital Universitari de Terrassa, Terrassa, Barcelona, Spain; Medicine Department, Universitat Internacional de Catalunya, Barcelona, Spain. Electronic address: leoabo@yahoo.es.; Pareja Sierra T; Department of Geriatric Medicine, Hospital Universitario de Guadalajara, Universidad de Alcalá, Alcalá de Henares, Madrid, Spain.; Sáez-López P; Department of Geriatric Medicine, Fundación Alcorcón University Hospital, Alcorcón, Madrid, Spain; La Paz Hospital Research Institute (IdiPAZ), Madrid, Spain; Spanish National Hip Fracture Registry, Madrid, Spain.; Etxebarria-Foronda I; Department of Orthopedic Surgery, Alto Deba Hospital, Arrasate/Mondragón, Gipuzkoa, Spain.; Caeiro Rey JR; Orthopaedic and Trauma Department, Clinic University Hospital of Santiago de Compostela, Santiago de Compostela, A Coruña, Spain; Surgery Department, University of Santiago de Compostela, Santiago de Compostela, A Coruña, Spain. |
| Source: | Revista espanola de geriatria y gerontologia [Rev Esp Geriatr Gerontol] 2025 May-Jun; Vol. 60 (3), pp. 101582. Date of Electronic Publication: 2024 Dec 17. |
| Publication Type: | Journal Article; Review |
| Language: | English; Spanish; Castilian |
| Journal Info: | Publisher: Elsevier España Country of Publication: Spain NLM ID: 8009022 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1578-1747 (Electronic) Linking ISSN: 0211139X NLM ISO Abbreviation: Rev Esp Geriatr Gerontol Subsets: MEDLINE |
| Imprint Name(s): | Publication: Madrid : Elsevier España; Original Publication: [Madrid] Sociedad Española de Gerontología y Geriatriía. |
| MeSH Terms: | Osteoporosis*/drug therapy ; Osteoporosis*/complications ; Osteoporotic Fractures*/prevention & control ; Bone Density Conservation Agents*/therapeutic use ; Bone Density Conservation Agents*/adverse effects ; Secondary Prevention*; Humans ; Aged ; Aged, 80 and over ; Treatment Outcome |
| Abstract: | Osteoporosis is a systemic skeletal disease characterized by low bone mass and deterioration of the microarchitecture, resulting in bone fragility and risk of fractures. As the life expectancy of the population increases, fragility fractures are expected to become more common. Indeed, the incidence rate for major fracture (hip, vertebra, pelvis, etc.) is highest among the population of adults aged 80 and over. Despite this, in Spain, three out of four patients who have experienced a fragility fracture do not receive drug treatment for the secondary prevention of new fractures. Therefore, it is crucial to raise awareness among healthcare professionals of the need to assess imminent fracture risk in older patients who have already sustained a fragility fracture and to initiate a rapid, appropriate, effective, and safe secondary fracture prevention strategy. The various clinical guidelines on secondary prevention of fragility fractures published to date do not reflect the heterogeneity of older adults. The aim of this paper is to provide a brief description of the available scientific evidence on the efficacy and safety of pharmacological treatments for osteoporosis in older adults and to submit a position paper proposed by the Spanish Society of Osteoporotic Fractures (SEFRAOS), which places greater emphasis on the specifics of the approach to and treatment of older adults who have sustained a fragility fracture.; (Copyright © 2024 SEGG. Publicado por Elsevier España, S.L.U. All rights reserved.) |
| Contributed Indexing: | Keywords: Ancianos; Fractura por fragilidad; Fragilidad; Fragility fracture; Frailty; Older adults; Osteoporosis; Prevención secundaria; Secondary prevention |
| Substance Nomenclature: | 0 (Bone Density Conservation Agents) |
| Entry Date(s): | Date Created: 20241218 Date Completed: 20250429 Latest Revision: 20250429 |
| Update Code: | 20260130 |
| DOI: | 10.1016/j.regg.2024.101582 |
| PMID: | 39693819 |
| Database: | MEDLINE |
Journal Article; Review