Impact of microabrasion and a remineralizing agent before in-office bleaching on hydrogen peroxide permeability, color alteration, and enamel morphology.
| Title: | Impact of microabrasion and a remineralizing agent before in-office bleaching on hydrogen peroxide permeability, color alteration, and enamel morphology. |
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| Authors: | Favoreto MW; Department of Restorative Dentistry, State University of Ponta Grossa, Parana, Brazil; Department of Restorative Dentistry, Tuiuti University of Parana, Curitiba, Parana, Brazil. Electronic address: michaelfavoreto@hotmail.com.; Condolo L; Department of Restorative Dentistry, State University of Ponta Grossa, Parana, Brazil. Electronic address: leticiaccondolo@gmail.com.; Camargo CM; Department of Restorative Dentistry, State University of Ponta Grossa, Parana, Brazil. Electronic address: cami254631@gmail.com.; Lima RR; Laboratory of Functional and Structural Biology, Institute of Biological Sciences, Federal University of Pará, Belém, Brazil. Electronic address: rafalima@ufpa.br.; Carrillo K; Facultad de Ciencias de la Salud, Carrera de Odontologia, Universidad Hemisferios, Quito, Ecuador. Electronic address: kjcarrillor@profesores.uhemisferios.edu.ec.; Calixto AL; Department of Restorative Dentistry, State University of Ponta Grossa, Parana, Brazil. Electronic address: alcalixto@ig.com.br.; Reis A; Department of Restorative Dentistry, State University of Ponta Grossa, Parana, Brazil. Electronic address: reis_ale@hotmail.com.; Loguercio AD; Department of Restorative Dentistry, State University of Ponta Grossa, Parana, Brazil; Facultad de Ciencias de la Salud, Carrera de Odontologia, Universidad Hemisferios, Quito, Ecuador. Electronic address: aloguercio@hotmail.com. |
| Source: | Journal of dentistry [J Dent] 2025 May; Vol. 156, pp. 105655. Date of Electronic Publication: 2025 Mar 01. |
| Publication Type: | Journal Article |
| Language: | English |
| Journal Info: | Publisher: Elsevier Country of Publication: England NLM ID: 0354422 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-176X (Electronic) Linking ISSN: 03005712 NLM ISO Abbreviation: J Dent Subsets: MEDLINE |
| Imprint Name(s): | Publication: Kidlington : Elsevier; Original Publication: Bristol, Eng., Wright. |
| MeSH Terms: | Hydrogen Peroxide*/pharmacokinetics ; Hydrogen Peroxide*/pharmacology ; Dental Enamel*/drug effects ; Dental Enamel*/ultrastructure ; Tooth Bleaching*/methods ; Caseins*/pharmacology ; Tooth Bleaching Agents*/pharmacokinetics ; Tooth Bleaching Agents*/pharmacology ; Tooth Remineralization*/methods ; Enamel Microabrasion*/methods; Bicuspid/drug effects ; Dental Pulp Cavity/drug effects ; Dental Enamel Permeability/drug effects ; Humans ; Microscopy, Electron, Scanning ; Color ; Spectrophotometry |
| Abstract: | Objective: This in vitro study evaluated hydrogen peroxide (HP) penetration into the pulp chamber, bleaching efficacy, and surface enamel morphology of human teeth subjected to enamel microabrasion (MA) combined with in-office bleaching (IOB), with or without the application of casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) remineralizing agent.; Methods: Forty sound premolars were randomly divided into four groups: no treatment (NT), IOB only (IOB), MA followed by IOB (MA+IOB), and MA followed by CPP-ACP and then IOB (MA+CPP-ACP+IOB). HP concentration in the pulp chamber was measured using UV-Vis spectrophotometry, while bleaching efficacy was assessed with a digital spectrophotometer. Surface morphology was analyzed using scanning electron microscopy (SEM), and data were statistically analyzed.; Results: The NT group exhibited lower HP penetration compared to experimental groups, while MA+IOB showed higher HP levels than IOB and MA+CPP-ACP+IOB. All experimental groups demonstrated significant color changes, except NT. The MA+IOB group displayed more grooves on enamel surfaces than the MA+CPP-ACP+IOB group, which had remineralizing agent deposits.; Conclusion: Combining MA and IOB increases HP penetration into the pulp chamber, but using CPP-ACP after MA can mitigate this effect without compromising bleaching efficacy.; Clinical Significance: Employing a CPP-ACP remineralizing agent post-microabrasion can help reduce HP levels in the pulp chamber while maintaining effective whitening.; (Copyright © 2025. Published by Elsevier Ltd.) |
| Competing Interests: | Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. |
| Contributed Indexing: | Keywords: Dental enamel permeability; Dentin permeability; Enamel microabrasion; Hydrogen Peroxide |
| Substance Nomenclature: | BBX060AN9V (Hydrogen Peroxide); 0 (Caseins); 0 (Tooth Bleaching Agents); 0 (casein phosphopeptide-amorphous calcium phosphate nanocomplex) |
| Entry Date(s): | Date Created: 20250302 Date Completed: 20250418 Latest Revision: 20250418 |
| Update Code: | 20260130 |
| DOI: | 10.1016/j.jdent.2025.105655 |
| PMID: | 40024516 |
| Database: | MEDLINE |
Journal Article