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Congenital neoplasms in cattle: a literature review and multi-institutional case series.

Title: Congenital neoplasms in cattle: a literature review and multi-institutional case series.
Authors: Sosa E; Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible (IPADS, INTA Balcarce-CONICET), Balcarce, Argentina.; Giannitti F; Instituto Nacional de Investigación Agropecuaria (INIA), Estación Experimental La Estanzuela, Colonia, Uruguay.; Macías-Rioseco M; California Animal Health and Food Safety (CAHFS) Laboratory, Tulare branch, University of California-Davis, Davis, CA, USA.; Colque Caro LA; Instituto de Investigación Animal del Chaco Semiárido (IIACS), INTA Salta, Salta, Argentina.; Silveira CDS; Instituto Nacional de Investigación Agropecuaria (INIA), Estación Experimental La Estanzuela, Colonia, Uruguay.; García JA; Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible (IPADS, INTA Balcarce-CONICET), Balcarce, Argentina.; Scioli MV; Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible (IPADS, INTA Balcarce-CONICET), Balcarce, Argentina.; Morrell E; Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible (IPADS, INTA Balcarce-CONICET), Balcarce, Argentina.; Moore DP; Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible (IPADS, INTA Balcarce-CONICET), Balcarce, Argentina.; Chianini F; Moredun Research Institute, Penicuik, Scotland, UK.; Cantón GJ; Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible (IPADS, INTA Balcarce-CONICET), Balcarce, Argentina.
Source: Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc [J Vet Diagn Invest] 2025 Jul; Vol. 37 (4), pp. 559-573. Date of Electronic Publication: 2025 Mar 11.
Publication Type: Journal Article; Review
Language: English
Journal Info: Publisher: Sage Country of Publication: United States NLM ID: 9011490 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1943-4936 (Electronic) Linking ISSN: 10406387 NLM ISO Abbreviation: J Vet Diagn Invest Subsets: MEDLINE
Imprint Name(s): Publication: 2011-: Thousand Oaks, CA : Sage; Original Publication: 1989-2004 : Columbia, MO : American Association of Veterinary Laboratory Diagnosticians
MeSH Terms: Cattle Diseases*/congenital ; Cattle Diseases*/pathology ; Cattle Diseases*/epidemiology ; Neoplasms*/veterinary ; Neoplasms*/congenital ; Neoplasms*/pathology; Uruguay/epidemiology ; United States/epidemiology ; Argentina/epidemiology ; United Kingdom/epidemiology ; Cattle ; Animals ; Female ; Animals, Newborn ; Pregnancy ; Male
Abstract: Congenital neoplasms are rare and sporadic in cattle and can cause losses due to abortions and perinatal or neonatal deaths. The etiopathogenesis of congenital tumors in bovine fetuses and neonates is largely unknown, and their diagnosis is often challenging. Here we review the literature on congenital tumors in cattle and report 11 additional cases diagnosed at veterinary diagnostic laboratories in Argentina, Uruguay, the United States, and the United Kingdom, namely 4 congenital lymphomas, 3 mesotheliomas, 2 adenomatoid tumors, 1 lymphangioma, and 1 ovarian sex cord-stromal tumor in bovine fetuses and/or neonatal calves. Lymphomas, mesotheliomas, melanomas, and mast cell tumors were reported most commonly in the literature.
Competing Interests: Declaration of conflicting interestsThe authors declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
Contributed Indexing: Keywords: bovine; cancer; congenital neoplasms; neonatal neoplasia
Entry Date(s): Date Created: 20250312 Date Completed: 20250626 Latest Revision: 20250626
Update Code: 20260130
PubMed Central ID: PMC11904926
DOI: 10.1177/10406387251324512
PMID: 40070027
Database: MEDLINE

Journal Article; Review