Intracardiac thrombus discovered incidentally during respiratory distress in an 18-month-old infant: case report.
| Title: | Intracardiac thrombus discovered incidentally during respiratory distress in an 18-month-old infant: case report. |
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| Authors: | Aarjouni Y; Department of Anesthesiology and Critical Care, Mohammed V Military Training Hospital, University Mohammed V of Rabat, Rabat, Morocco.; Absa Y; Department of Anesthesiology and Critical Care, The Children's Hospital of Rabat, University Mohammed V of Rabat, Morocco.; Sayouti C; Department of Anesthesiology and Critical Care, The Children's Hospital of Rabat, University Mohammed V of Rabat, Morocco.; Dafali L; Department of Anesthesiology and Critical Care, The Children's Hospital of Rabat, University Mohammed V of Rabat, Morocco.; Bentalha A; Department of Anesthesiology and Critical Care, The Children's Hospital of Rabat, University Mohammed V of Rabat, Morocco.; Kettani SE; Department of Anesthesiology and Critical Care, The Children's Hospital of Rabat, University Mohammed V of Rabat, Morocco. |
| Source: | The Pan African medical journal [Pan Afr Med J] 2025 Jan 13; Vol. 50, pp. 24. Date of Electronic Publication: 2025 Jan 13 (Print Publication: 2025). |
| Publication Type: | Case Reports; Journal Article |
| Language: | English |
| Journal Info: | Publisher: African Field Epidemiology Network Country of Publication: Uganda NLM ID: 101517926 Publication Model: eCollection Cited Medium: Internet ISSN: 1937-8688 (Electronic) NLM ISO Abbreviation: Pan Afr Med J Subsets: MEDLINE |
| Imprint Name(s): | Original Publication: Kampala, Uganda : African Field Epidemiology Network |
| MeSH Terms: | Thrombosis*/diagnosis ; Thrombosis*/drug therapy ; Heart Diseases*/diagnosis ; Heart Diseases*/drug therapy ; Respiratory Insufficiency*/etiology; Anticoagulants/administration & dosage ; Heparin/administration & dosage ; Dobutamine/administration & dosage ; Furosemide/administration & dosage ; Cyanosis/etiology ; Hypoxia/etiology ; Humans ; Infant ; Echocardiography ; Male ; Incidental Findings |
| Abstract: | Intracardiac thrombi (ICT) are uncommon in the pediatric population and can lead to significant morbidity and mortality. This case highlights a unique instance of a giant ICT in an 18-month-old infant with no notable medical history, contributing to the understanding of hypercoagulable states and their implications in pediatric patients. The patient presented with respiratory distress, characterized by a flu-like syndrome, cyanosis, and hypoxemia. Initial examination revealed lethargy and significant respiratory distress, with imaging showing lobar pneumonia and an echocardiogram revealing a 32 mm x22 mm heterogeneous mass in the left ventricle. Further investigations confirmed the mass was a thrombus, attributed to deficiencies in proteins C and S. The patient was treated with dobutamine to enhance contractility, furosemide for diuresis, and heparin for anticoagulation. There was a favorable progression, with gradual weaning from oxygen and complete resolution of the thrombus by day 15. This case underscores the importance of recognizing hypercoagulable states in pediatric patients with ICT. It suggests that medical management can be an effective alternative to surgical interventions. Moreover, it emphasizes the need for further research to establish optimal treatment protocols for pediatric ICT, particularly regarding the risks associated with thrombus size and ventricular function.; (Copyright: Youssef Aarjouni et al.) |
| Competing Interests: | The authors declare no competing interests. |
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| Contributed Indexing: | Keywords: Intracardiac thrombus; case report; pediatric; thrombophilia |
| Substance Nomenclature: | 0 (Anticoagulants); 9005-49-6 (Heparin); 3S12J47372 (Dobutamine); 7LXU5N7ZO5 (Furosemide) |
| Entry Date(s): | Date Created: 20250505 Date Completed: 20250505 Latest Revision: 20250516 |
| Update Code: | 20260130 |
| PubMed Central ID: | PMC12049141 |
| DOI: | 10.11604/pamj.2025.50.24.45613 |
| PMID: | 40322328 |
| Database: | MEDLINE |
Case Reports; Journal Article