Long-Term (5-Years) Outcomes of Current Drug-Eluting Stents in Percutaneous Coronary Intervention: A Network Meta-Analysis of Randomized Controlled Trials.
| Title: | Long-Term (5-Years) Outcomes of Current Drug-Eluting Stents in Percutaneous Coronary Intervention: A Network Meta-Analysis of Randomized Controlled Trials. |
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| Authors: | Goyal A; Department of Internal Medicine, Cleveland Clinic Foundation, Cleveland, Ohio, USA.; Saeed H; Department of Internal Medicine, Rawalpindi Medical University, Rawalpindi, Punjab, Pakistan.; Hurjkaliani S; Department of Internal Medicine, Dow University of Health Sciences, Karachi, Pakistan.; Mashkoor Y; Department of Internal Medicine, Dow University of Health Sciences, Karachi, Pakistan.; Abdullah; Department of Internal Medicine, Rawalpindi Medical University, Rawalpindi, Punjab, Pakistan.; Mahalwar G; Department of Internal Medicine, Cleveland Clinic Foundation, Cleveland, Ohio, USA.; Kalra A; Department of Cardiology, Franciscan Health, Lafayette, Indiana, USA.; Krannert Cardiovascular Research Center, Indiana University School of Medicine, Indianapolis, Indiana, USA.; Reed GW; Department of Cardiovascular Medicine, Heart, Vascular and Thoracic Institute, Cleveland Clinic Foundation, Cleveland, Ohio, USA. |
| Source: | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions [Catheter Cardiovasc Interv] 2025 Aug; Vol. 106 (2), pp. 1196-1211. Date of Electronic Publication: 2025 Jun 05. |
| Publication Type: | Journal Article; Network Meta-Analysis; Systematic Review |
| Language: | English |
| Journal Info: | Publisher: Wiley-Liss Country of Publication: United States NLM ID: 100884139 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-726X (Electronic) Linking ISSN: 15221946 NLM ISO Abbreviation: Catheter Cardiovasc Interv Subsets: MEDLINE |
| Imprint Name(s): | Original Publication: New York, NY : Wiley-Liss, c1999- |
| MeSH Terms: | Coronary Artery Disease*/mortality ; Coronary Artery Disease*/therapy ; Coronary Artery Disease*/diagnostic imaging ; Percutaneous Coronary Intervention*/adverse effects ; Percutaneous Coronary Intervention*/mortality ; Percutaneous Coronary Intervention*/instrumentation ; Drug-Eluting Stents*; Coronary Thrombosis/etiology ; Aged ; Female ; Humans ; Male ; Middle Aged ; Odds Ratio ; Prosthesis Design ; Randomized Controlled Trials as Topic ; Risk Assessment ; Risk Factors ; Time Factors ; Treatment Outcome |
| Abstract: | Background: Various drug-eluting stents (DES) are currently used for percutaneous coronary intervention (PCI). However, long-term trials reveal inconsistent results in head-to-head comparisons.; Aims: To conduct a network meta-analysis of relevant trials to assess the performance of different DES currently used in PCI.; Methods: We systematically searched major databases for randomized controlled trials (RCTs) reporting 5-year outcomes of currently used DES and conducted a network meta-analysis using a frequentist random-effects model with odds ratios (ORs) as effect measures. DES were ranked by P-scores across several outcomes, with definite/probable stent thrombosis as the primary outcome. Statistical analyses were conducted in R software (v4.4.1), with significance set at p |
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| Grant Information: | The authors received no specific funding for this work. |
| Contributed Indexing: | Keywords: cardiac death; drug‐eluting stents; myocardial infarction; network meta‐analysis; stent thrombosis; target lesion failure; target lesion revascularization |
| Entry Date(s): | Date Created: 20250605 Date Completed: 20250811 Latest Revision: 20250813 |
| Update Code: | 20260130 |
| PubMed Central ID: | PMC12336763 |
| DOI: | 10.1002/ccd.31668 |
| PMID: | 40470578 |
| Database: | MEDLINE |
Journal Article; Network Meta-Analysis; Systematic Review