Endoscopic full-thickness resection using full-thickness resection device for treatment of upper and lower gastrointestinal tract lesions-the first New Zealand study.
| Title: | Endoscopic full-thickness resection using full-thickness resection device for treatment of upper and lower gastrointestinal tract lesions-the first New Zealand study. |
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| Authors: | Yiu SW; Medical Registrar, Gastroenterology and Hepatology Department, Counties Manukau District Health Board, Auckland, New Zealand.; Horsfall E; Gastroenterology Advanced Trainee, Gastroenterology and Hepatology Department, Counties Manukau District Health Board, Auckland, New Zealand.; Ogra R; Gastroenterologist, Gastroenterology and Hepatology Department, Counties Manukau District Health Board, Auckland, New Zealand.; Schauer C; Gastroenterologist, Gastroenterology and Hepatology Department, Waitematā District Health Board, Auckland, New Zealand.; Sekra A; Gastroenterologist, Gastroenterology and Hepatology Department, Counties Manukau District Health Board, Auckland, New Zealand. |
| Source: | The New Zealand medical journal [N Z Med J] 2025 Jun 06; Vol. 138 (1616), pp. 43-49. Date of Electronic Publication: 2025 Jun 06. |
| Publication Type: | Journal Article; Multicenter Study |
| Language: | English |
| Journal Info: | Publisher: Pasifika Medical Association Group Country of Publication: New Zealand NLM ID: 0401067 Publication Model: Electronic Cited Medium: Internet ISSN: 1175-8716 (Electronic) Linking ISSN: 00288446 NLM ISO Abbreviation: N Z Med J Subsets: MEDLINE |
| Imprint Name(s): | Publication: 2022- : Auckland : Pasifika Medical Association Group; Original Publication: Wellington : New Zealand Medical Association |
| MeSH Terms: | Gastrointestinal Neoplasms*/surgery ; Endoscopy, Gastrointestinal*/instrumentation ; Endoscopy, Gastrointestinal*/methods; Postoperative Complications/epidemiology ; Humans ; Male ; Female ; Middle Aged ; Retrospective Studies ; New Zealand ; Aged ; Aged, 80 and over ; Adult |
| Abstract: | Aim: The full-thickness resection device (FTRD) offers an innovative treatment approach for lesions unsuitable for traditional endoscopic resection. This study evaluates FTRD's safety and efficacy for resection of upper and lower gastrointestinal tract lesions in New Zealand, where data are currently lacking.; Method: This multicentre retrospective study included patients who underwent FTRD at Middlemore Hospital and North Shore Hospital between 1 January 2017 and 30 April 2023. Histology and post-procedural complications up to 30 days were collated. Ethics approval and locality assessment were granted.; Results: A total of 51 patients-18 males (35%) and 33 (65%) females-with a mean age of 63.5 years were included. Five lesions were upper gastrointestinal (four gastric body; one duodenal) and 46 were colonic cases (20 appendiceal orifice lesions; five caecal; four from hepatic flexure; two each at sigmoid, ascending and transverse colon; one descending colon and 10 from the rectum). Technically successful FTRD deployment was achieved in 86% (n=44), with negative histological margins (R0 resection) seen in 82% (n=31). Thirteen patients were excluded from this calculation, as histological clearance was not applicable. Procedure-related complications occurred in 12% (n=6): there were three appendicitis cases; one experienced delayed bleeding requiring blood transfusion and endoscopic management; and two experienced technical complications (one snare entrapment and one clip entrapment).; Conclusion: This study demonstrates our experience with FTRD in New Zealand with technical success and R0 resection rates similar to the published literature. There is a considerable adverse event rate that requires careful patient discussion and consent prior to selection of this procedure.; (© PMA.) |
| Competing Interests: | Nil. |
| Entry Date(s): | Date Created: 20250605 Date Completed: 20250605 Latest Revision: 20250717 |
| Update Code: | 20260130 |
| DOI: | 10.26635/6965.6893 |
| PMID: | 40472361 |
| Database: | MEDLINE |
Journal Article; Multicenter Study