Phylogenetic insights into the transmission dynamics of arthropod-borne viruses.
| Title: | Phylogenetic insights into the transmission dynamics of arthropod-borne viruses. |
|---|---|
| Authors: | Hill V; Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT, USA.; Dellicour S; Spatial Epidemiology Lab, Université Libre de Bruxelles, Brussels, Belgium.; Department of Microbiology, Immunology and Transplantation, Rega Institute, KU Leuven, Leuven, Belgium.; Interuniversity Institute of Bioinformatics in Brussels, Université Libre de Bruxelles, Vrije Universiteit Brussel, Brussels, Belgium.; Giovanetti M; Department of Sciences and Technologies for Sustainable Development and One Health, Università Campus Bio-Medico di Roma, Rome, Italy.; Instituto René Rachou, Fundação Oswaldo Cruz, Belo Horizonte, Brazil.; Climate Amplified Diseases and Epidemics, Rio de Janeiro, Brazil.; Grubaugh ND; Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT, USA. nathan.grubaugh@yale.edu.; Department of Ecology and Evolutionary Biology, Yale University, New Haven, CT, USA. nathan.grubaugh@yale.edu. |
| Source: | Nature reviews. Genetics [Nat Rev Genet] 2026 Jan; Vol. 27 (1), pp. 47-61. Date of Electronic Publication: 2025 Jun 06. |
| Publication Type: | Journal Article; Review |
| Language: | English |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 100962779 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1471-0064 (Electronic) Linking ISSN: 14710056 NLM ISO Abbreviation: Nat Rev Genet Subsets: MEDLINE |
| Imprint Name(s): | Original Publication: London, UK : Nature Pub. Group, [2000- |
| MeSH Terms: | Arboviruses*/genetics ; Arboviruses*/classification ; Arthropod Vectors*/virology ; Arthropods*/virology ; Arbovirus Infections*/transmission ; Arbovirus Infections*/virology ; Arbovirus Infections*/epidemiology ; Phylogeny*; Animals ; Humans |
| Abstract: | Arthropod-borne viruses (arboviruses) impose substantial global health and economic burdens, affecting both human and animal populations. These viruses - including dengue, chikungunya, Rift Valley fever, Crimean-Congo haemorrhagic fever and bluetongue viruses - have complex transmission cycles involving vertebrate hosts and arthropod vectors. Their circulation in livestock and wildlife complicate surveillance, as traditional epidemiological approaches rely mainly on human clinical data. Climate change and increasing global interconnectedness are accelerating their emergence and invasion, necessitating a deeper understanding of their ecological and epidemiological dynamics. Advances in genomic surveillance and phylogenetics can provide insights into spatial and temporal patterns of virus transmission that are difficult to obtain through traditional surveillance systems. By integrating phylogenetic models with ecological and epidemiological data, we can better detect and respond to arbovirus introductions, spillovers and outbreaks that are relevant to both human and veterinary health.; (© 2025. Springer Nature Limited.) |
| Competing Interests: | Competing interests: The authors declare no competing interests. |
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| Grant Information: | DP2 AI176740 United States AI NIAID NIH HHS; U01 AI151698 United States AI NIAID NIH HHS |
| Entry Date(s): | Date Created: 20250606 Date Completed: 20251206 Latest Revision: 20251207 |
| Update Code: | 20260130 |
| PubMed Central ID: | PMC12257617 |
| DOI: | 10.1038/s41576-025-00854-x |
| PMID: | 40481331 |
| Database: | MEDLINE |
Journal Article; Review