A Retrospective Study of Nonsurgical Management Options for Permanent Filler Complications of the Gluteal Region.
| Title: | A Retrospective Study of Nonsurgical Management Options for Permanent Filler Complications of the Gluteal Region. |
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| Authors: | Decates TS; From the Department of Dermatology, Erasmus Medical Center, Rotterdam, The Netherlands.; Schoonen T; From the Department of Dermatology, Erasmus Medical Center, Rotterdam, The Netherlands.; Onderdijk AJ; From the Department of Dermatology, Erasmus Medical Center, Rotterdam, The Netherlands.; van Leerdam M; Bare Statistics, Stompetoren, The Netherlands.; Velthuis PJ; From the Department of Dermatology, Erasmus Medical Center, Rotterdam, The Netherlands. |
| Source: | Plastic and reconstructive surgery. Global open [Plast Reconstr Surg Glob Open] 2025 Jun 06; Vol. 13 (6), pp. e6815. Date of Electronic Publication: 2025 Jun 06 (Print Publication: 2025). |
| Publication Type: | Journal Article |
| Language: | English |
| Journal Info: | Publisher: Wolters Kluwer Health/Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 101622231 Publication Model: eCollection Cited Medium: Print ISSN: 2169-7574 (Print) Linking ISSN: 21697574 NLM ISO Abbreviation: Plast Reconstr Surg Glob Open Subsets: PubMed not MEDLINE |
| Imprint Name(s): | Original Publication: [Philadelphia, PA] : Wolters Kluwer Health/Lippincott Williams & Wilkins, [2013]- |
| Abstract: | Background: Gluteal or hip augmentation with nonresorable (permanent) fillers can lead to complications. Nonsurgical treatment options are unclear and are mainly based on case reports. This study aimed to examine which treatment option is the better choice for patients with complications after permanent fillers in the buttocks.; Methods: In this retrospective cohort study, the data of patients visiting our hospital clinic with complications between 2016 and 2021 after gluteal or hip augmentation with fillers were analyzed. Contingency table analyses were conducted to determine which of the 5 types of treatments, minocycline, surgery, intralesional laser treatment (ILT), pressure garments, and omega-3 supplements, were related to pain relief and softening of the nodules.; Results: Seventy-two patients (69 women and 3 men; mean age, 39 y) were selected. Inclusion criteria were men and women older than 18 years of age with complications after gluteal or thigh augmentation with permanent fillers. Filler material was mainly found in the buttocks and hips. Treatment options were antibiotics, surgery, laser, pressure garment, and omega-3 supplements. Pain relief was reported in 36 of the 42 responders. Softening of the nodules appeared to be positively associated with ILT (odds ratio = 20.25).; Conclusions: The most common complication was subcutaneous inflammation (panniculitis) in the buttocks and hips. Most patients reported reduced pain and softening of the nodules after treatment. The latter outcome appears to be related to the ILT. Considering the information in the literature and our findings, a step-by-step treatment protocol was developed.; (Copyright © 2025 The Authors. Published by Wolters Kluwer Health, Inc. on behalf of The American Society of Plastic Surgeons.) |
| Competing Interests: | The authors have no financial interest to declare in relation to the content of this article. |
| References: | Dermatol Surg. 2019 Aug;45(8):1085-1094. (PMID: 30789508); Plast Reconstr Surg. 2006 Sep;118(3 Suppl):77S-84S. (PMID: 16936547); Plast Reconstr Surg. 2018 Jun;141(6):1361-1369. (PMID: 29750756); Plast Reconstr Surg. 2013 Oct;132(4):522e-529e. (PMID: 24076699); Mult Scler Relat Disord. 2020 Sep;44:102311. (PMID: 32593958); J Forensic Sci. 2018 Sep;63(5):1406-1412. (PMID: 29464686); Ann Plast Surg. 2009 Jan;62(1):12-4. (PMID: 19131711); Plast Reconstr Surg. 2001 Mar;107(3):734-41. (PMID: 11304599); Forensic Sci Int. 2016 Feb;259:e1-4. (PMID: 26704422); Aesthetic Plast Surg. 2020 Dec;44(6):1997-2007. (PMID: 32936330); Aesthet Surg J. 2014 May 1;34(4):571-7. (PMID: 24676144); J Clin Aesthet Dermatol. 2013 Mar;6(3):46-9. (PMID: 23556038); Aesthet Surg J. 2017 May 1;37(5):560-569. (PMID: 28203698); Dermatol Ther. 2015 Mar-Apr;28(2):98-101. (PMID: 25649644); Aesthetic Plast Surg. 2022 Jun;46(3):1388-1397. (PMID: 34939150); Front Immunol. 2021 Feb 05;11:623052. (PMID: 33613558); Ann Med Surg (Lond). 2021 Sep 03;69:102771. (PMID: 34522373); J Am Acad Dermatol. 2005 Feb;52(2 Suppl 1):53-6. (PMID: 15692516); Front Psychol. 2018 Sep 19;9:1742. (PMID: 30283387); Behav Res Methods. 2018 Feb;50(1):195-212. (PMID: 28342071); J Cosmet Dermatol. 2022 May;21(5):1967-1972. (PMID: 35049130); Dermatol Surg. 2009 Oct;35 Suppl 2:1689-95. (PMID: 19807765); Plast Reconstr Surg Glob Open. 2022 Nov 28;10(11):e4687. (PMID: 36448011); Dermatol Surg. 2022 Feb 1;48(2):220-224. (PMID: 34935756); J Plast Reconstr Aesthet Surg. 2012 Jan;65(1):29-34. (PMID: 21885359); Aesthetic Plast Surg. 2023 Feb;47(1):245-259. (PMID: 35999464); Toxicol Rep. 2021 Jan 27;8:303-314. (PMID: 33552929); J Cutan Med Surg. 2020 Sep/Oct;24(5):481-494. (PMID: 32463305); Plast Reconstr Surg. 2011 Jun;127(6):121e-123e. (PMID: 21617422); Dermatol Ther. 2006 May-Jun;19(3):159-68. (PMID: 16784515); Aesthet Surg J Open Forum. 2022 Jun 20;4:ojac051. (PMID: 35979376) |
| Entry Date(s): | Date Created: 20250609 Latest Revision: 20250611 |
| Update Code: | 20260130 |
| PubMed Central ID: | PMC12144638 |
| DOI: | 10.1097/GOX.0000000000006815 |
| PMID: | 40487830 |
| Database: | MEDLINE |
Journal Article