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Factors associated with heart failure severity and mortality in Butembo between 2021 and 2023.

Title: Factors associated with heart failure severity and mortality in Butembo between 2021 and 2023.
Authors: Paluku Mwalitsa JP; Medicine, Catholic University of Graben, Butembo, Democratic Republic of the Congo.; Mbo Mukongole JP; Medicine, University of Kisangani, Butembo, Democratic Republic of the Congo.; Tsongo Kibendelwa Z; Medicine, University of Kisangani, Butembo, Democratic Republic of the Congo.; Kambale Munyambalu D; Medicine, Catholic University of Graben, Butembo, Democratic Republic of the Congo.; Sahika SM; Medicine, Catholic University of Graben, Butembo, Democratic Republic of the Congo.; Katsuva Mbahweka F; Medicine, Catholic University of Graben, Butembo, Democratic Republic of the Congo.; Nzanzu Arma F; Medicine, Catholic University of Graben, Butembo, Democratic Republic of the Congo.; Muhindo Muyisa R; Medicine, Catholic University of Graben, Butembo, Democratic Republic of the Congo. Electronic address: rolandmuyisam@gmail.com.; Kambale N; Medicine, Catholic University of Graben, Butembo, Democratic Republic of the Congo.; Nzanzu Kalima A; Medicine, Catholic University of Graben, Butembo, Democratic Republic of the Congo.; Kasereka Masumbuko C; Medicine, Catholic University of Graben, Butembo, Democratic Republic of the Congo. Electronic address: claudemasumbuko@gmail.com.
Source: Current problems in cardiology [Curr Probl Cardiol] 2025 Sep; Vol. 50 (9), pp. 103122. Date of Electronic Publication: 2025 Jun 30.
Publication Type: Journal Article; Review
Language: English
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7701802 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1535-6280 (Electronic) Linking ISSN: 01462806 NLM ISO Abbreviation: Curr Probl Cardiol Subsets: MEDLINE
Imprint Name(s): Publication: [Amsterdam] : Elsevier; Original Publication: Chicago, Year Book Medical Publishers.
MeSH Terms: Heart Failure*/mortality ; Heart Failure*/epidemiology ; Heart Failure*/diagnosis ; Heart Failure*/physiopathology ; Quality of Life*; Survival Rate/trends ; Humans ; Male ; Female ; Middle Aged ; Severity of Illness Index ; Aged ; Risk Factors
Abstract: Background: Heart failure is a syndrome with high morbidity and mortality, influenced by various regional factors.; Objective: This study aimed to enhance heart failure management by identifying factors that can improve the quality of life and survival of patients in eastern DR Congo.; Methods: Conducted from January 1, 2022, to December 31, 2023, this descriptive analytical study included 156 heart failure patients (mean age 62 ± 15), comprising 80 males and 76 females. Each patient was followed for 12 months.; Results: The frequency of heart failure was 17.5 % (156 out of 2732 patients) at the cardiology center. Severity correlated with the use of indigenous anti-poison products (p 0.000) and valvular heart disease (p 0.000). Mortality was notably influenced by indigenous anti-poison product use (41.2 % mortality; p 0.000), duration of diabetes (≤ 1 year 7.4 %; 2-5 years 11.1 %; > 5 years 33.3 %; p 0.014), dilated cardiomyopathy (18.9 % vs. 1.2 % for non-dilated; p 0.000), and valvular heart disease (17.5 % vs. 1.3 %; p 0.003). Mortality rates varied by heart failure phenotype (HFrEF 30.9 %, HFmEF 5.1 %, HFpEF 0.0 %; p 0.000) and severity (NYHA IV 55.6 % vs. NYHA I and II 0.0 %).; Conclusion: Indigenous anti-poison products and rheumatic valvular heart disease contribute to the worsening and premature death of heart failure patients. Addressing these factors may improve patient survival in this region.; (Copyright © 2025 Elsevier Inc. All rights reserved.)
Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
Contributed Indexing: Keywords: Butembo; Factors; Heart failure; Mortality; Severity
Entry Date(s): Date Created: 20250702 Date Completed: 20250730 Latest Revision: 20250730
Update Code: 20260130
DOI: 10.1016/j.cpcardiol.2025.103122
PMID: 40602736
Database: MEDLINE

Journal Article; Review