Low-density lipoprotein cholesterol management after acute coronary syndrome in Aotearoa New Zealand: opportunities for improvement (ANZACS-QI 81).
| Title: | Low-density lipoprotein cholesterol management after acute coronary syndrome in Aotearoa New Zealand: opportunities for improvement (ANZACS-QI 81). |
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| Authors: | He JL; Cardiology advanced trainee, Counties Manukau District Health Board, New Zealand.; Lee M; Biostatistician, Counties Manukau District Health Board, New Zealand.; Kerr AJ |
| Source: | The New Zealand medical journal [N Z Med J] 2025 Jul 11; Vol. 138 (1618), pp. 60-74. Date of Electronic Publication: 2025 Jul 11. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Language: | English |
| Journal Info: | Publisher: Pasifika Medical Association Group Country of Publication: New Zealand NLM ID: 0401067 Publication Model: Electronic Cited Medium: Internet ISSN: 1175-8716 (Electronic) Linking ISSN: 00288446 NLM ISO Abbreviation: N Z Med J Subsets: MEDLINE |
| Imprint Name(s): | Publication: 2022- : Auckland : Pasifika Medical Association Group; Original Publication: Wellington : New Zealand Medical Association |
| MeSH Terms: | Acute Coronary Syndrome*/blood ; Acute Coronary Syndrome*/drug therapy ; Cholesterol, LDL*/blood ; Hydroxymethylglutaryl-CoA Reductase Inhibitors*/therapeutic use; New Zealand/epidemiology ; Humans ; Male ; Female ; Middle Aged ; Aged ; Quality Improvement ; Registries ; Coronary Angiography ; Medication Adherence ; Adult |
| Abstract: | Aim: Our aims are to describe low-density lipoprotein (LDL) management in the year after a first acute coronary syndrome (ACS) hospitalisation and identify opportunities to further improve management.; Methods: Thirteen thousand two hundred and two patients aged over 20 years of age presenting with their first ACS (2014 to 2019), who underwent coronary angiography in the Northern Region of Aotearoa New Zealand, were identified from the All New Zealand All Cardiology Services Quality Improvement (ANZACS-QI) registry. De-identified linkage with Northern Region TestSafe and National Pharmaceutical databases enabled tracking of LDL levels and statin dispensing. Statin adherence in the year post-discharge was estimated using a medication possession ratio (MPR) with an MPR=1 defined as optimal coverage.; Results: Seventy-eight percent (n=10,395) of patients had a repeat lipid study within 12 months. Of these, 78.6% received post-discharge dispensing of high-intensity statin. Mean LDL fell from 2.691.14mmol/L in-hospital to 1.920.85mmol/L post-discharge. A total of 2,484 (23.9%) patients achieved LDL |
| Competing Interests: | AK: Co-chair ANZACS-QI governance group. Te Whatu Ora Counties Manukau provided support for this manuscript. |
| Grant Information: | Te Whatu Ora Counties Manukau provided support for this manuscript. |
| Substance Nomenclature: | 0 (Cholesterol, LDL); 0 (Hydroxymethylglutaryl-CoA Reductase Inhibitors) |
| Entry Date(s): | Date Created: 20250710 Date Completed: 20250710 Latest Revision: 20250721 |
| Update Code: | 20260130 |
| DOI: | 10.26635/6965.6818 |
| PMID: | 40638930 |
| Database: | MEDLINE |
Journal Article; Research Support, Non-U.S. Gov't