Impact of early decompression surgery and injury characteristics on neurological recovery following traumatic cervical spinal cord injury.
| Title: | Impact of early decompression surgery and injury characteristics on neurological recovery following traumatic cervical spinal cord injury. |
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| Authors: | Trung ND; Department of Surgical and Transplant Intensive Care Unit, Military Central Hospital 108, Viet Nam.; Su HX; Institute of Biomedicine and Pharmacy, Vietnam Military Medical University, HanoiViet Nam.; Chinh DT; Department of Surgical and Transplant Intensive Care Unit, Military Central Hospital 108, Viet Nam.; Tam NC; Department of Surgical and Transplant Intensive Care Unit, Military Central Hospital 108, Viet Nam.; Khanh LN; Department of Surgical and Transplant Intensive Care Unit, Military Central Hospital 108, Viet Nam.; Van Nam D; Department of Surgical and Transplant Intensive Care Unit, Military Central Hospital 108, Viet Nam. |
| Source: | Brain & spine [Brain Spine] 2025 Jul 10; Vol. 5, pp. 104326. Date of Electronic Publication: 2025 Jul 10 (Print Publication: 2025). |
| Publication Type: | Journal Article |
| Language: | English |
| Journal Info: | Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 9918470888906676 Publication Model: eCollection Cited Medium: Internet ISSN: 2772-5294 (Electronic) Linking ISSN: 27725294 NLM ISO Abbreviation: Brain Spine Subsets: PubMed not MEDLINE |
| Imprint Name(s): | Original Publication: [Amsterdam] : Elsevier B.V., [2021]- |
| Abstract: | Introduction: Traumatic cervical spinal cord injury (SCI) frequently leads to severe neurological deficits. Early decompressive surgery, when performed shortly after the injury, is believed to improve outcomes. However, the impact of surgical timing, calculated from the moment of injury, and injury characteristics on neurological recovery remains poorly understood.; Research Question: This study aims to assess the impact of early decompressive surgery and injury characteristics on neurological recovery in traumatic cervical SCI patients.; Material and Methods: A retrospective case-control study was conducted at the 108 Central Military Hospital in Hanoi, Vietnam, between January 2018 and June 2023. Data collected included demographics, injury characteristics, time from injury to decompression surgery, and clinical outcomes at the 1-year follow-up.; Results: Among the 193 patients initially screened, 156 met the inclusion criteria. Neurological recovery was observed in 44.2 % of patients. Early decompression within 24 h significantly improved recovery outcomes (OR = 3.12, p = 0.006). Injury at C1-C3 levels, longer spinal cord injury length, and severe spinal canal stenosis were associated with poorer recovery (OR = 0.34, p = 0.015; OR = 0.21, p |
| Competing Interests: | The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. |
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| Contributed Indexing: | Keywords: Cervical spinal cord injury; Early decompression surgery; Neurological recovery; Prognostic factors; Spinal cord injury length |
| Entry Date(s): | Date Created: 20250721 Latest Revision: 20250723 |
| Update Code: | 20260130 |
| PubMed Central ID: | PMC12274716 |
| DOI: | 10.1016/j.bas.2025.104326 |
| PMID: | 40689129 |
| Database: | MEDLINE |
Journal Article