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A Comparative Analysis of Global Responses to Monkeypox Outbreaks: Lessons Learned and Future Directions - a Mini Narrative Review.

Title: A Comparative Analysis of Global Responses to Monkeypox Outbreaks: Lessons Learned and Future Directions - a Mini Narrative Review.
Authors: Anjum AF; Department of Public Health & Community Medicine, Shaikh Khalifa Bin Zayed Al-Nahyan Medical College, Shaikh Zayed Postgraduate Medical Institute (SZPGMI), Lahore, PB, Pakistan.; Anjum MB; Akhtar Saeed Medical and Dental College, Lahore, Pakistan.; Rehman RU; Department of Public Health & Community Medicine, Shaikh Khalifa Bin Zayed Al-Nahyan Medical College, Shaikh Zayed Postgraduate Medical Institute (SZPGMI), Lahore, PB, Pakistan.; Wei CR; Department of Research and Development, Shing Huei Group, Taipei, Taiwan.; Akilimali A; Department of Research, Medical Research Circle (MedReC), Goma, DR Congo.; Humayun A; Department of Public Health & Community Medicine, Shaikh Zayed Postgraduate Medical Institute (SZPGMI), Lahore, Pakistan.
Source: Annals of medicine and surgery (2012) [Ann Med Surg (Lond)] 2025 Jul 16; Vol. 87 (8), pp. 5098-5105. Date of Electronic Publication: 2025 Jul 16 (Print Publication: 2025).
Publication Type: Journal Article; Review
Language: English
Journal Info: Publisher: Wolters Kluwer Country of Publication: England NLM ID: 101616869 Publication Model: eCollection Cited Medium: Print ISSN: 2049-0801 (Print) Linking ISSN: 20490801 NLM ISO Abbreviation: Ann Med Surg (Lond) Subsets: PubMed not MEDLINE
Imprint Name(s): Publication: 2023- : [London] : Wolters Kluwer; Original Publication: London : Surgical Associates Ltd., 2012-
Abstract: Background and Aims: The widespread of Mpox, a zoonotic disease, beyond its endemic regions and declaration of Mpox as a public health emergency by WHO, has raised a global concern. This study aims to compare and analyze the response of various regions across the globe to recent Mpox outbreaks, identify key lessons learned, and propose future strategies to improve public health preparedness.; Methods: We conducted a narrative review using PubMed, Google Scholar, and Scopus to identify peer-reviewed articles and official reports published between 2022 and 2024. Countries were selected based on geographic diversity, incidence rates, and data availability. Key comparison parameters included timing of interventions, vaccine rollout, public awareness, diagnostic capacity, and resource allocation. A regionally stratified, thematic analysis was performed to assess the effectiveness of national responses to the Mpox outbreak.; Results: The analysis indicates that there is a high degree of dispersion in the measured outcomes of responses. Countries with a pre-implemented vaccination plan like the UK and USA presented with much lower infection rate than the countries that took reactive measures. Awareness activities in high-risk areas, together with quarantine measures, caused a tremendous reduction of transmission. Nevertheless, there were visible chinks in the knowledge-sharing and funding in global health and this led to higher incidence of infection among the communities with limited access to resources like Nigeria and DRC.; Conclusion: This narrative review demonstrates the importance of customized global coordination and flexibility of public health responses when dealing with emerging infectious diseases. The different regional responses underscore the essentiality of nuanced interventions, early detection, and effective public health messaging. While some territories have been highly proactive and shown excellent management of the situation, others are struggling with resource constraints and a less well-informed population. Future efforts to provide disaster relief should place a greater emphasis on global collaboration, health system strengthening, and training public health professionals. The world can draw lessons from what has worked well or not so well with the current Mpox response to help prepare and mitigate future public health emergency.; (Copyright © 2025 The Author(s). Published by Wolters Kluwer Health, Inc.)
Competing Interests: Sponsorships or competing interests that may be relevant to content are disclosed at the end of this article. All authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
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Contributed Indexing: Keywords: Mpox; communicable disease control; crisis intervention; disease outbreak; epidemics; global health; immunization programs; public health infrastructure
Entry Date(s): Date Created: 20250811 Latest Revision: 20250813
Update Code: 20260130
PubMed Central ID: PMC12333850
DOI: 10.1097/MS9.0000000000003577
PMID: 40787494
Database: MEDLINE

Journal Article; Review