Decoding Fear: Analysis and Prognosis of Preoperatory Stress Level Through Advanced Statistical Modelling-A Prospective Study Across Multiple Surgical Specialties.
| Title: | Decoding Fear: Analysis and Prognosis of Preoperatory Stress Level Through Advanced Statistical Modelling-A Prospective Study Across Multiple Surgical Specialties. |
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| Authors: | Dascălu CG; Department of Medical Informatics and Biostatistics, Faculty of Medicine, 'Grigore T. Popa' University of Medicine and Pharmacy, 16 University Street, 700115 Iasi, Romania.; Cucu AI; Faculty of Medicine and Biological Sciences, University Stefan cel Mare of Suceava, 720229 Suceava, Romania.; Vovciuc A; Faculty of Medicine and Biological Sciences, University Stefan cel Mare of Suceava, 720229 Suceava, Romania.; Axinte S; Faculty of Medicine and Biological Sciences, University Stefan cel Mare of Suceava, 720229 Suceava, Romania.; Suceava County Emergency Clinical Hospital, 720237 Suceava, Romania.; Turliuc S; Faculty of Medicine, University of Medicine and Pharmacy Grigore T. Popa Iasi, 700115 Iasi, Romania.; Bobu AM; Faculty of Medicine, University of Medicine and Pharmacy Grigore T. Popa Iasi, 700115 Iasi, Romania.; Clinical Emergency Hospital St. Spiridon, 700111 Iasi, Romania.; Tamas C; Faculty of Medicine, University of Medicine and Pharmacy Grigore T. Popa Iasi, 700115 Iasi, Romania.; Clinical Emergency Hospital St. Spiridon, 700111 Iasi, Romania.; Porumb V; Faculty of Medicine, University of Medicine and Pharmacy Grigore T. Popa Iasi, 700115 Iasi, Romania.; Patrascanu E; Faculty of Medicine, University of Medicine and Pharmacy Grigore T. Popa Iasi, 700115 Iasi, Romania.; Buzduga CM; Faculty of Medicine, University of Medicine and Pharmacy Grigore T. Popa Iasi, 700115 Iasi, Romania.; Clinical Emergency Hospital St. Spiridon, 700111 Iasi, Romania.; Blanaru PA; Faculty of Medicine, University of Medicine and Pharmacy Grigore T. Popa Iasi, 700115 Iasi, Romania.; Morosan AP; Faculty of Medicine, University of Medicine and Pharmacy Grigore T. Popa Iasi, 700115 Iasi, Romania.; Clinical Emergency Hospital St. Spiridon, 700111 Iasi, Romania.; Prutianu I; Faculty of Medicine, University of Medicine and Pharmacy Grigore T. Popa Iasi, 700115 Iasi, Romania.; Covali R; Faculty of Medical Bioengineering, University of Medicine and Pharmacy Grigore T. Popa Iasi, 700115 Iasi, Romania.; Pruteanu AI; Faculty of Medicine, University of Medicine and Pharmacy Grigore T. Popa Iasi, 700115 Iasi, Romania.; Costea CF; Faculty of Medicine, University of Medicine and Pharmacy Grigore T. Popa Iasi, 700115 Iasi, Romania.; Carauleanu A; Faculty of Medicine, University of Medicine and Pharmacy Grigore T. Popa Iasi, 700115 Iasi, Romania. |
| Source: | Medical sciences (Basel, Switzerland) [Med Sci (Basel)] 2025 Sep 05; Vol. 13 (3). Date of Electronic Publication: 2025 Sep 05. |
| Publication Type: | Journal Article |
| Language: | English |
| Journal Info: | Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 101629322 Publication Model: Electronic Cited Medium: Internet ISSN: 2076-3271 (Electronic) Linking ISSN: 20763271 NLM ISO Abbreviation: Med Sci (Basel) Subsets: MEDLINE |
| Imprint Name(s): | Original Publication: Basel, Switzerland : MDPI AG, [2013]- |
| MeSH Terms: | Stress, Psychological*/psychology ; Fear*/psychology ; Specialties, Surgical*; Humans ; Female ; Male ; Prospective Studies ; Middle Aged ; Adult ; Aged ; Prognosis ; Models, Statistical ; Preoperative Period |
| Abstract: | Background: Preoperative stress is a multifactorial phenomenon shaped by physiological, psychological, and social influences, with a substantial impact on postoperative recovery. This study aimed to quantify preoperative stress levels, identify associated factors, and rank their predictive importance. Methods: A prospective study was conducted on 197 patients scheduled for general surgery, orthopedics, neurosurgery, or otorhinolaryngology procedures between December 2024 and June 2025 at Suceava County Emergency Clinical Hospital. Stress levels were assessed using the Brief Measure of Emotional Preoperative Stress (B-MEPS), translated and culturally adapted into Romanian. Statistical analyses included nonparametric tests, generalized linear modeling, and Random Forest regression. Results: The mean B-MEPS score was 21.42 ± 6.04 (range: 11-34), indicating a moderate level of preoperative stress. Higher stress scores were significantly associated with female sex (p < 0.001), lower educational attainment (p = 0.003), divorced marital status (p = 0.007), a history of cancer (p = 0.002), and the type of surgical intervention (p = 0.003). Random Forest analysis identified the type of surgery, educational level, and sex as the strongest predictors. Conclusions: Preoperative stress is chiefly influenced by the type of surgical procedure, educational level, and sex, with potential synergistic effects among these factors. Early identification of high-risk patients enables targeted, personalized interventions to mitigate anxiety and improve perioperative outcomes. Further research should include formal validation of the Romanian version of B-MEPS and the integration of additional psychosocial variables. |
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| Contributed Indexing: | Keywords: B-MEPS; anxiety; predictors; preoperative stress; random forest; surgery |
| Entry Date(s): | Date Created: 20250922 Date Completed: 20250922 Latest Revision: 20250925 |
| Update Code: | 20260130 |
| PubMed Central ID: | PMC12452544 |
| DOI: | 10.3390/medsci13030181 |
| PMID: | 40981179 |
| Database: | MEDLINE |
Journal Article