Prevalence of Disorders of Gut-Brain Interaction in Indonesian Adolescents: Has It Increased during the Coronavirus Disease Pandemic?
| Title: | Prevalence of Disorders of Gut-Brain Interaction in Indonesian Adolescents: Has It Increased during the Coronavirus Disease Pandemic? |
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| Authors: | Darma A; Department of Child Health, Dr. Soetomo General Academic Hospital, Surabaya, East Java, Indonesia.; Department of Child Health, Faculty of Medicine Universitas Airlangga, Surabaya, East Java, Indonesia.; Nesa NNM; Department of Child Health, Dr. Soetomo General Academic Hospital, Surabaya, East Java, Indonesia.; Department of Child Health, Faculty of Medicine Universitas Airlangga, Surabaya, East Java, Indonesia.; Department of Child Health, Faculty of Medicine Universitas Udayana, Denpasar, Bali, Indonesia.; Sumitro KR; Department of Child Health, Dr. Soetomo General Academic Hospital, Surabaya, East Java, Indonesia.; Department of Child Health, Faculty of Medicine Universitas Airlangga, Surabaya, East Java, Indonesia.; Rokhayati E; Department of Child Health, Faculty of Medicine, Universitas Sebelas Maret, Surakarta, Central Java, Indonesia.; Budiyanto; Department of Child Health, Dr. Soetomo General Academic Hospital, Surabaya, East Java, Indonesia.; Department of Child Health, Faculty of Medicine Universitas Airlangga, Surabaya, East Java, Indonesia.; Department of Child Health, Ulin Regional Hospital, Faculty of Medicine and Health Sciences, Universitas Lambung Mangkurat, Banjarmasin, South Kalimantan, Indonesia.; Tallo KT; Departement of Child Health, SK Lerik General Hospital, Kupang, East Nusa Tenggara, Indonesia.; Department of Child Health, Mamami Hospital, Kupang, East Nusa Tenggara, Indonesia.; Ariyanti NR; Department of Child Health, Dr. Soetomo General Academic Hospital, Surabaya, East Java, Indonesia.; Department of Child Health, Faculty of Medicine Universitas Airlangga, Surabaya, East Java, Indonesia.; Department of Child Health, Mohammad Saleh Hospital, Probolinggo, East Java, Indonesia.; Retnaningtyas LP; Department of Child Health, Faculty of Medicine, Universitas Surabaya, Surabaya, East Java, Indonesia.; Febryani DDSM; Departement of Child Health, Arifin Achmad General Academic Hospital, Pekanbaru, Riau, Indonesia.; Department of Child Health, Universitas Riau, Pekanbaru, Riau, Indonesia.; Malino IY; Department of Child Health, Dian Harapan Hospital, Jayapura, Papua, Indonesia.; Brahmantya H; Departement of Child Health, Abdoel Wahab Sjahranie General Hospital, Samarinda, East Kalimantan, Indonesia.; Department of Child Health, Faculty of Medicine, Mulawarman University, Samarinda, East Kalimantan, Indonesia.; Wenas W; Department of Child Health, Santa Elisabeth Hospital, Batam, Riau Island, Indonesia.; Athiyyah AF; Department of Child Health, Dr. Soetomo General Academic Hospital, Surabaya, East Java, Indonesia.; Department of Child Health, Faculty of Medicine Universitas Airlangga, Surabaya, East Java, Indonesia.; Ranuh RG; Department of Child Health, Dr. Soetomo General Academic Hospital, Surabaya, East Java, Indonesia.; Department of Child Health, Faculty of Medicine Universitas Airlangga, Surabaya, East Java, Indonesia.; Sudarmo SM; Department of Child Health, Dr. Soetomo General Academic Hospital, Surabaya, East Java, Indonesia.; Department of Child Health, Faculty of Medicine Universitas Airlangga, Surabaya, East Java, Indonesia. |
| Source: | Pediatric gastroenterology, hepatology & nutrition [Pediatr Gastroenterol Hepatol Nutr] 2025 Sep; Vol. 28 (5), pp. 302-311. Date of Electronic Publication: 2025 Sep 09. |
| Publication Type: | Journal Article |
| Language: | English |
| Journal Info: | Publisher: Korean Society of Pediatric Gastroenterology, Hepatology and Nutrition Country of Publication: Korea (South) NLM ID: 101590471 Publication Model: Print-Electronic Cited Medium: Print ISSN: 2234-8646 (Print) Linking ISSN: 22348840 NLM ISO Abbreviation: Pediatr Gastroenterol Hepatol Nutr Subsets: PubMed not MEDLINE |
| Imprint Name(s): | Original Publication: Seongnam : Korean Society of Pediatric Gastroenterology, Hepatology and Nutrition |
| Abstract: | Purpose: The prevalence of disorders of gut-brain interaction (DGBI), previously known as functional gastrointestinal disorders, has increased among children and adolescents, impacting their quality of life. Lifestyle changes during the coronavirus disease (COVID-19) pandemic, such as decreased physical activity and altered dietary habits, may have contributed to this increase rise. This study aimed to assess the prevalence of DGBIs among Indonesian adolescents during the COVID-19 pandemic using the Rome IV diagnostic criteria.; Methods: A cross-sectional survey was conducted from March 2022 to April 2023 involving 5,247 adolescents (aged 13-18 years) from nine provinces in Indonesia (Riau, Riau Islands, Central Java, East Java, Bali, South Kalimantan, East Kalimantan, East Nusa Tenggara, and Papua). Data were collected via online and offline versions of the Rome IV questionnaire and analyzed descriptively to determine DGBI prevalence rates by age, sex, and region.; Results: The prevalence of DGBIs was greater in females than males and among adolescents living in urban areas. We found that 28.4% of adolescents were diagnosed with at least one DGBI, with functional constipation being the most prevalent (21.8%), followed by functional dyspepsia (4.5%). Additionally, 13.5% of respondents experienced two overlapping DGBIs, and 1.3% suffered from three overlapping DGBIs simultaneously. The prevalence rate of DGBI varied significantly across the participating provinces.; Conclusion: DGBIs are highly prevalent among Indonesian adolescents after the COVID-19 pandemic. These findings can guide public health strategies to address adolescent gastrointestinal health in Indonesia and other regions.; (Copyright © 2025 by The Korean Society of Pediatric Gastroenterology, Hepatology and Nutrition.) |
| Competing Interests: | Conflict of Interest: The authors have no financial conflicts of interest. |
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| Contributed Indexing: | Keywords: Adolescent; COVID-19; Disorders of Gut-Brain Interactio; Indonesia; Rome IV criteria |
| Entry Date(s): | Date Created: 20250926 Date Completed: 20250926 Latest Revision: 20250928 |
| Update Code: | 20260130 |
| PubMed Central ID: | PMC12457811 |
| DOI: | 10.5223/pghn.2025.28.5.302 |
| PMID: | 41001442 |
| Database: | MEDLINE |
Journal Article