The role of enhanced stent visualization imaging in percutaneous coronary intervention: a systematic review of efficacy and clinical outcomes.
| Title: | The role of enhanced stent visualization imaging in percutaneous coronary intervention: a systematic review of efficacy and clinical outcomes. |
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| Authors: | Sant Bakshsingh V; Department of Cardiology, Grange University Hospital, Cwmbran, UK.; Bundhoo SS; Department of Cardiology, Grange University Hospital, Cwmbran, UK.; Protty MB; Systems Immunity Research Institute, Cardiff University, Cardiff, UK.; Department of Cardiology, University Hospital of Wales, Cardiff, UK. |
| Source: | Expert review of cardiovascular therapy [Expert Rev Cardiovasc Ther] 2025 Dec; Vol. 23 (12), pp. 915-921. Date of Electronic Publication: 2025 Oct 14. |
| Publication Type: | Journal Article; Systematic Review |
| Language: | English |
| Journal Info: | Publisher: Taylor & Francis Country of Publication: England NLM ID: 101182328 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1744-8344 (Electronic) Linking ISSN: 14779072 NLM ISO Abbreviation: Expert Rev Cardiovasc Ther Subsets: MEDLINE |
| Imprint Name(s): | Publication: 2015- : Abingdon, Oxford : Taylor & Francis; Original Publication: London, UK : Future Drugs Ltd. |
| MeSH Terms: | Percutaneous Coronary Intervention*/methods ; Coronary Artery Disease*/diagnostic imaging ; Coronary Artery Disease*/therapy ; Coronary Artery Disease*/surgery ; Stents*; Fluoroscopy/methods ; Coronary Angiography/methods ; Tomography, Optical Coherence/methods ; Ultrasonography, Interventional/methods ; Humans ; Treatment Outcome |
| Abstract: | Introduction: Coronary artery disease (CAD) is a major global cause of morbidity and mortality. Percutaneous coronary intervention (PCI) is central to its management, and optimal stent deployment is critical. This systematic review evaluates the efficacy and clinical outcomes associated with enhanced stent visualization (ESV) systems - X-ray-based fluoroscopic tools such as StentBoost and CLEARstent - in PCI.; Methods: A systematic literature search of PubMed, PubMed Central, and Cochrane Library was conducted according to PRISMA guidelines. Inclusion criteria comprised all study types evaluating ESV use in PCI, excluding case reports and non-English articles. Study quality was assessed using Newcastle-Ottawa tool.; Results: Twelve studies involving ESV were included. ESV improved detection of stent expansion and deployment versus standard angiography and showed strong agreement with OCT and IVUS. ESV-guided PCI was associated with reduced rates of major adverse cardiac events (MACE), particularly in long-term follow-up. Radiation exposure was modestly increased but deemed acceptable.; Conclusions: ESV systems enhance stent deployment accuracy and clinical outcomes in PCI, offering a cost-effective and accessible alternative to OCT and IVUS. Evidence supports routine integration of ESV in PCI workflows, although further large-scale trials are warranted.; Registration: PROSPERO identifier is CRD420251020834. |
| Contributed Indexing: | Keywords: CLEARstent; StentBoost; clear stent; coronary angiography; coronary artery disease; fluoroscopy; percutaneous coronary intervention; stent boost |
| Entry Date(s): | Date Created: 20251011 Date Completed: 20251212 Latest Revision: 20260105 |
| Update Code: | 20260130 |
| DOI: | 10.1080/14779072.2025.2574262 |
| PMID: | 41074697 |
| Database: | MEDLINE |
Journal Article; Systematic Review