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Habitual Physical Activity and Sedentary Behavior as Predictors of Mortality in Older Adults: A Longitudinal Study With 5 Years of Follow-Up.

Title: Habitual Physical Activity and Sedentary Behavior as Predictors of Mortality in Older Adults: A Longitudinal Study With 5 Years of Follow-Up.
Authors: Galvão LL; Physical Education and Sports Center, Federal University of Espírito Santo, Vitória, ES, Brazil.; Santos LD; Health Sciences Complex, Faculty of Medicine, State University of Tocantins, Augustinópolis, TO, Brazil.; Vieira LA; Physical Education and Sports Center, Federal University of Espírito Santo, Vitória, ES, Brazil.; Santos DAT; Department of Education, Collegiate of Physical Education, State University of Bahia, Teixeira de Freitas, BA, Brazil.; de Lira CAB; Faculty of Physical Education and Dance, Federal University of Goiás, Goiânia, GO, Brazil.; Virtuoso Júnior JS; Department of Sport Sciences, Federal University of Triângulo Mineiro, Uberaba, MG, Brazil.; Prates FM; Biochemistry, Carvalho Clinical Analysis Laboratory, Teixeira de Freitas, BA, Brazil.; Andrade MS; Department of Physiology, Federal University of São Paulo, São Paulo, SP, Brazil.; Weiss K; Institute of Primary Care, University of Zurich, Zurich, Switzerland.; Knechtle B; Institute of Primary Care, University of Zurich, Zurich, Switzerland.; Medbase St. Gallen Am Vadianplatz, St. Gallen, Switzerland.; Vancini RL; Physical Education and Sports Center, Federal University of Espírito Santo, Vitória, ES, Brazil.
Source: Journal of aging and physical activity [J Aging Phys Act] 2025 Oct 11, pp. 1-10. Date of Electronic Publication: 2025 Oct 11.
Publication Model: Ahead of Print
Publication Type: Journal Article
Language: English
Journal Info: Publisher: Human Kinetics Publishers, Inc Country of Publication: United States NLM ID: 9415639 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1543-267X (Electronic) Linking ISSN: 10638652 NLM ISO Abbreviation: J Aging Phys Act Subsets: MEDLINE
Imprint Name(s): Original Publication: Champaign, IL : Human Kinetics Publishers, Inc., c1993-
Abstract: Background: It is essential to study the various relationships between habitual physical activity (HPA), sedentary behavior (SB), and mortality.; Objectives: To explore the predictive capacity of HPA and SB for all-cause mortality and assess the mortality risk associated with the cutoff points predicted.; Methods: Prospective cohort study, comprising 332 older adults of both sexes. HPA and SB were assessed using the International Physical Activity Questionnaire. Receiver operating characteristic analysis was used to evaluate the predictive capacity of HPA and SB with mortality. Mortality risks were assessed by Cox regression, with a 95% confidence interval and hazard ratio estimation.; Results: HPA and SB demonstrated good accuracy in predicting mortality, based on 150 and 40 min/week of HPA and 495 and 380 min/day of SB, respectively, for men and women. Based on the mentioned cutoff points, both behaviors were found to be associated with the risk of mortality for females, while for males, an association was observed only with SB. In the combined analysis, low HPA practice was identified as a risk factor for mortality, in both sexes.; Conclusion: HPA and SB are good predictors of mortality, each with its own associated risks. Additionally, both exhibit different sensitivity and specificity values according to sex. Significance/Implications: We demonstrate that HPA and SB can be used as screening for end-of-life outcomes and can be used in public policies and specific cutoff points, especially for SB.
Contributed Indexing: Keywords: death; epidemiology; motor activity; sedentary lifestyle
Entry Date(s): Date Created: 20251012 Latest Revision: 20251012
Update Code: 20260130
DOI: 10.1123/japa.2024-0305
PMID: 41077415
Database: MEDLINE

Journal Article