The nature of the relation between mental well-being and ill-being.
| Title: | The nature of the relation between mental well-being and ill-being. |
|---|---|
| Authors: | Tamnes CK; PROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway. c.k.tamnes@psykologi.uio.no.; Division of Mental Health and Substance Abuse, Diakonhjemmet Hospital, Oslo, Norway. c.k.tamnes@psykologi.uio.no.; Bekkhus M; PROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway.; Eilertsen M; PROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway.; Division of Public Health and Prevention, Norwegian Institute of Public Health, Oslo, Norway.; Nes RB; PROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway.; Division of Public Health and Prevention, Norwegian Institute of Public Health, Oslo, Norway.; Department of Philosophy, Classics, and History of Arts and Ideas, University of Oslo, Oslo, Norway.; Prydz MB; PROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway.; Division of Public Health and Prevention, Norwegian Institute of Public Health, Oslo, Norway.; Ystrom E; PROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway.; PsychGen Center for Genetic Epidemiology and Mental Health, Norwegian Institute of Public Health, Oslo, Norway.; Centre for Research on Equality in Education, University of Oslo, Oslo, Norway.; Aksnes ER; PROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway.; Division of Mental Health and Substance Abuse, Diakonhjemmet Hospital, Oslo, Norway.; Andersen SN; PROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway.; Department of Sociology and Human Geography, University of Oslo, Oslo, Norway.; Ask H; PROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway.; Division of Public Health and Prevention, Norwegian Institute of Public Health, Oslo, Norway.; PsychGen Center for Genetic Epidemiology and Mental Health, Norwegian Institute of Public Health, Oslo, Norway.; Ayorech Z; PROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway.; Baier T; Department of Sociology and Human Geography, University of Oslo, Oslo, Norway.; WZB Berlin Social Science Center, Einstein Center Population Diversity, Berlin, Germany.; Beck D; PROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway.; Division of Mental Health and Substance Abuse, Diakonhjemmet Hospital, Oslo, Norway.; Berger EJ; PROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway.; Department of Sociology and Human Geography, University of Oslo, Oslo, Norway.; Bjørndal LD; PROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway.; Boer OD; PROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway.; Department of Psychology, Education and Child Studies, Erasmus School of Social and Behavioral Sciences, Erasmus University Rotterdam, Rotterdam, the Netherlands.; Department of Child and Adolescent Psychiatry, Sophia Children's Hospital, Erasmus Medical Center, Rotterdam, the Netherlands.; Bos MGN; Developmental and Educational Psychology Unit, Institute of Psychology, Leiden University, Leiden, the Netherlands.; Leiden Institute for Brain and Cognition, Leiden University, Leiden, the Netherlands.; Caspi A; PROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway.; Psychology and Neuroscience, Duke University, Durham, NC, USA.; Cheesman R; PROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway.; PsychGen Center for Genetic Epidemiology and Mental Health, Norwegian Institute of Public Health, Oslo, Norway.; Chegeni R; PROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway.; Cortés-García L; PROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway.; Department of Psychology, University of Science and Technology, Trondheim, Norway.; Demange PA; PROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway.; Ebeltoft JC; PROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway.; Edvoll M; PROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway.; Eftedal NH; PROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway.; Eilertsen EM; PROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway.; Fang Y; PROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway.; Ferschmann L; PROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway.; Norwegian Centre for Violence and Traumatic Stress Studies, Oslo, Norway.; Fluit S; PROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway.; Folstad SH; PROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway.; Fredriksen E; Department of Psychology, University of Oslo, Oslo, Norway.; Gashi L; PROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway.; Department of Sociology and Human Geography, University of Oslo, Oslo, Norway.; Gustavson K; Division of Public Health and Prevention, Norwegian Institute of Public Health, Oslo, Norway.; Department of Psychology, University of Oslo, Oslo, Norway.; Hansen T; PROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway.; Division of Public Health and Prevention, Norwegian Institute of Public Health, Oslo, Norway.; Hofgaard LS; PROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway.; Karl V; PROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway.; Kozák M; PROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway.; Norwegian Social Research, Oslo Metropolitan University, Oslo, Norway.; Krogshus KG; PROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway.; Institute of Health and Society, Faculty of Medicine, University of Oslo, Oslo, Norway.; Liu J; PROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway.; Lyngstad TH; Department of Sociology and Human Geography, University of Oslo, Oslo, Norway.; MacSweeney N; PROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway.; Division of Mental Health and Substance Abuse, Diakonhjemmet Hospital, Oslo, Norway.; Maes HHM; Virginia Institute for Psychiatric and Behavioral Genetics, Department of Human and Molecular Genetics, Virginia Commonwealth University, Richmond, VA, USA.; Mayerhofer L; PROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway.; McAdams TA; PROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway.; Social, Genetic & Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.; Moffitt TE; PROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway.; Psychology and Neuroscience, Duke University, Durham, NC, USA.; Naseri N; PROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway.; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.; Nilsen TS; Division of Public Health and Prevention, Norwegian Institute of Public Health, Oslo, Norway.; Norbom LB; PROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway.; Nygaard E; PROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway.; Oftedal A; Division of Public Health and Prevention, Norwegian Institute of Public Health, Oslo, Norway.; Pedersen W; Department of Sociology and Human Geography, University of Oslo, Oslo, Norway.; Norwegian Social Research, Oslo Metropolitan University, Oslo, Norway.; Qin Q; PROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway.; Rodríguez-Cano R; PROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway.; Department of Psychology, University of Science and Technology, Trondheim, Norway.; Skirbekk V; Department of Psychology, University of Oslo, Oslo, Norway.; Centre for Fertility and Health, Norwegian Institute of Public Health, Oslo, Norway.; Smajlagic D; PROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway.; Institute for Behavioral Genetics, University of Colorado Boulder, Boulder, CO, USA.; Solberg OM; PROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway.; Tandberg AD; PROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway.; Teulings IJE; PROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway.; Torvik FA; PROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway.; PsychGen Center for Genetic Epidemiology and Mental Health, Norwegian Institute of Public Health, Oslo, Norway.; Centre for Fertility and Health, Norwegian Institute of Public Health, Oslo, Norway.; Tsotsi S; PROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway.; Department of Nursing and Health Promotion, Oslo Metropolitan University, Oslo, Norway.; Ulset VS; PROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway.; Vira EG; PROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway.; Division of Public Health and Prevention, Norwegian Institute of Public Health, Oslo, Norway.; Røysamb E; PROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway.; Division of Public Health and Prevention, Norwegian Institute of Public Health, Oslo, Norway.; von Soest T; PROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway. |
| Source: | Nature human behaviour [Nat Hum Behav] 2025 Dec; Vol. 9 (12), pp. 2431-2440. Date of Electronic Publication: 2025 Oct 16. |
| Publication Type: | Journal Article; Review |
| Language: | English |
| Journal Info: | Publisher: Springer Nature Publishing Country of Publication: England NLM ID: 101697750 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2397-3374 (Electronic) Linking ISSN: 23973374 NLM ISO Abbreviation: Nat Hum Behav Subsets: MEDLINE |
| Imprint Name(s): | Original Publication: [London] : Springer Nature Publishing, [2017]- |
| MeSH Terms: | Mental Disorders*/psychology ; Mental Disorders*/genetics ; Mental Health* ; Personal Satisfaction*; Humans |
| Abstract: | Research on mental health has traditionally separated the study of ill-being, including clinically defined mental and behavioural disorders and subthreshold problems, from the study of well-being, which encompasses factors such as life satisfaction and positive affect. Although previous reviews of studies primarily using self-report scales indicate that ill-being and well-being are distinct yet interconnected constructs, a deeper examination of their relationship is lacking. In this Perspective, we synthesize genetic, biological, developmental, psychosocial, societal, cultural and clinical research on ill-being and well-being. Our review reveals substantial genetic overlap and similar biological underpinnings for ill-being and well-being. By contrast, environmental factors and societal changes often exert divergent influences. We propose a differentiated multidisciplinary framework in which the shared and unique determinants, predictors, mechanisms and consequences of mental ill-being and well-being vary across levels of analysis, offering a more nuanced understanding of the interconnections.; (© 2025. Springer Nature Limited.) |
| Competing Interests: | Competing interests: The authors declare no competing interests. |
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| Grant Information: | P2C HD065563 United States HD NICHD NIH HHS; R01 DA054313 United States DA NIDA NIH HHS |
| Entry Date(s): | Date Created: 20251016 Date Completed: 20251223 Latest Revision: 20260426 |
| Update Code: | 20260426 |
| PubMed Central ID: | PMC13109989 |
| DOI: | 10.1038/s41562-025-02319-x |
| PMID: | 41102498 |
| Database: | MEDLINE |
Journal Article; Review