Termination Processes of Pregnancies Due to Intrauterine Mort Fetus and Fetal Anomaly.
| Title: | Termination Processes of Pregnancies Due to Intrauterine Mort Fetus and Fetal Anomaly. |
|---|---|
| Authors: | Akcaoglu T; Department of Plastic and Reconstructive Surgery, Johns Hopkins University, School of Medicine, Baltimore, Maryland 21287, United States.; Department of Obstetrics and Gynecology, Istanbul Medipol University, School of Medicine, Istanbul 34214, Turkiye.; Eren EC; Department of Obstetrics and Gynecology, Istanbul Medipol University, School of Medicine, Istanbul 34214, Turkiye. |
| Source: | Maternal-fetal medicine (Wolters Kluwer Health, Inc.) [Matern Fetal Med] 2025 Oct; Vol. 7 (4), pp. 228-233. Date of Electronic Publication: 2025 Aug 04. |
| Publication Type: | Journal Article |
| Language: | English |
| Journal Info: | Publisher: Wolters Kluwer Health, Inc Country of Publication: United States NLM ID: 101769241 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2641-5895 (Electronic) Linking ISSN: 26415895 NLM ISO Abbreviation: Matern Fetal Med Subsets: PubMed not MEDLINE |
| Imprint Name(s): | Original Publication: [New York, NY] : Wolters Kluwer Health, Inc., [2019]- |
| Abstract: | Objective: To compare pregnancy terminations for two reasons: intrauterine fetal death (IUFD) and fetal anomaly, focusing on obstetric data and termination processes to optimize clinical management.; Methods: This retrospective, single-center study included singleton pregnancies terminated for intrauterine fetal death or fetal anomaly (≥ 10 weeks' gestation) between January 2020 and December 2021. Demographic, obstetric, and procedural data were collected. Termination methods included misoprostol, balloon catheter, curettage, and hysterotomy, following FIGO guidelines. Feticide was performed when indicated. Statistical analysis was conducted using t-test, chi-square test, and Pearson correlation; significance was set at P < 0.050.; Results: A total of 173 termination cases (104 IUFD, 69 fetal anomalies) were analyzed. Mean gestational age was 16.6 ± 4.2 weeks. Termination and hospitalization times were longer in anomaly cases (P < 0.001). Gravida and parity were lower in the anomaly group (P = 0.005, P = 0.011). Misoprostol use showed a positive correlation with termination time (r = 0.251, P = 0.001); parity was negatively correlated (r = -0.175, P = 0.021). Balloon, curettage, and feticide rates were higher in anomaly cases (all P < 0.001). Complications occurred in 4 patients (2.3%).; Conclusion: Clinical approaches to pregnancy termination differ based on the underlying condition. Obstetric history and fetal pathology influence the methods and timing of the procedure, emphasizing the need for individualized care to improve patient outcomes.; (Copyright © 2025 The Chinese Medical Association, published by Wolters Kluwer Health, Inc.) |
| Competing Interests: | None. |
| References: | Obstet Gynecol. 1991 Jan;77(1):146-52. (PMID: 1984215); Eur J Obstet Gynecol Reprod Biol. 2017 Nov;218:73-84. (PMID: 28963922); Obstet Gynecol. 2005 Feb;105(2):352-6. (PMID: 15684164); J Matern Fetal Neonatal Med. 2015 Jan;28(1):93-6. (PMID: 24635496); Reprod Health Matters. 2008 May;16(31 Suppl):46-56. (PMID: 18772083); Cochrane Database Syst Rev. 2010 Oct 06;(10):CD000941. (PMID: 20927722); J Law Biosci. 2023 Sep 03;10(2):lsad023. (PMID: 37671116); Eur J Obstet Gynecol Reprod Biol. 2004 Mar 15;113(1):45-8. (PMID: 15036710); Contraception. 1994 Feb;49(2):111-4. (PMID: 8143450); MMWR Surveill Summ. 2024 Nov 28;73(7):1-28. (PMID: 39602470); Pak J Biol Sci. 2008 Nov 1;11(21):2505-8. (PMID: 19205272); Lancet. 1972 Aug 5;2(7771):279. (PMID: 4114530); BJOG. 2008 May;115(6):689-96. (PMID: 18410651); BMC Pregnancy Childbirth. 2022 Sep 6;22(1):688. (PMID: 36068489); J Matern Fetal Neonatal Med. 2018 Mar;31(5):677-681. (PMID: 28282779); J Matern Fetal Neonatal Med. 2016 Sep;29(17):2810-2. (PMID: 26452400); Eur J Obstet Gynecol Reprod Biol. 2019 Dec;243:139-143. (PMID: 31704530); Matern Fetal Med. 2024 Jul 1;6(3):131-133. (PMID: 40406285); Arch Gynecol Obstet. 2018 Nov;298(5):881-887. (PMID: 30167856); Obstet Gynecol. 1999 Feb;93(2):275-80. (PMID: 9932569) |
| Contributed Indexing: | Keywords: Abortion care; Fetal anomalies; Intrauterine fetal death; Pregnancy termination |
| Entry Date(s): | Date Created: 20251029 Date Completed: 20251029 Latest Revision: 20251031 |
| Update Code: | 20260130 |
| PubMed Central ID: | PMC12558279 |
| DOI: | 10.1097/FM9.0000000000000306 |
| PMID: | 41158430 |
| Database: | MEDLINE |
Journal Article